LOCUS BC046919 1349 bp mRNA linear HUM 15-SEP-2004
DEFINITION Homo sapiens tumor suppressor candidate 1, mRNA (cDNA clone
IMAGE:5466772), partial cds.
ACCESSION BC046919
VERSION BC046919.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1349)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1349)
AUTHORS Director MGC Project.
TITLE Direct Submission
JOURNAL Submitted (14-FEB-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 44 Row: k Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis.
FEATURES Location/Qualifiers
source 1..1349
/db_xref="H-InvDB:HIT000098393"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:5466772"
/tissue_type="Skin, melanoma, amelanotic"
/clone_lib="NIH_MGC_41"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..1349
/gene="TUSC1"
/gene_synonym="TSG-9"
/db_xref="GeneID:286319"
CDS <1..617
/gene="TUSC1"
/gene_synonym="TSG-9"
/codon_start=3
/product="TUSC1 protein"
/protein_id="AAH46919.1"
/db_xref="GeneID:286319"
/translation="GGATRRGSCCGGDGAADGRGPGRSGRARGGGSPSGGGGGVGWRG
RADGARQQLEERFADLAASHLEAIRARDEWDRQNARLRQENARLRLENRRLKRENRSL
FRQALRLPGEGGDGTPAEARRVPEEASTNRRARDSGREDEPGSPRALRARLEKLEAMY
RRALLQLHLEQRGPRPSGDKEEQPLQEPDSGLRSRDSEPSGPWL"
BASE COUNT 263 a 391 c 420 g 275 t
ORIGIN
1 gtggtggcgc cactaggcgc gggagttgct gcggcgggga cggtgctgcg gacggccgag
61 ggccaggccg ctccggccgg gctcgtggtg ggggcagccc cagcggcggc ggcggcggcg
121 tgggctggcg aggccgcgcg gacggcgccc gacagcagct ggaggagcgg tttgccgacc
181 tggcggcgag ccacttggag gccatccgtg cgcgggacga gtgggaccgg cagaacgcgc
241 ggctgcgtca ggagaacgcc cggctgcggc tcgagaaccg gcggctgaag cgcgagaacc
301 gcagcctctt ccgtcaggct ttgcggctcc ccggcgaagg cggcgacggg acgcccgcgg
361 aggcacgccg ggtccctgaa gaggccagca cgaaccggag ggctagagac agcggccgag
421 aggacgagcc gggcagcccc agggccctga gggcccgact tgagaagctg gaagccatgt
481 accgccgggc cctgctgcag ctgcacctcg agcagcgggg accacgtccg agcggggaca
541 aggaggagca gcctctacag gaacccgact ccggcctccg ctcccgggac tcggagccct
601 ctgggccctg gctgtagccg aggccgcagc cggtgagagg cggagcctcg agcgggcccc
661 tcctcctccg ttcccagcta cccccgacct cgcgcacgcc ctggcccgct ccctgcccgc
721 ggataccttg gactacggtg ccttcccgcc cccaccagtg gacacttccg ggtggcgctt
781 ggccatccgc ttggtggagg tcgagtgggt gcaagggccc tcaggacctc ccacatgtac
841 agttcccctg cctcttgccc cggctagttt ccctggagag aggcctagcc aacaacgaag
901 ggacggattt taaaacagcg agaactgggt gccaagaaac acttcatagt ccctgaactt
961 ttctggatgt tgtgcgaacc tgttgtattt ttttttttcc tgtattttgg ttctgaggga
1021 tgagtaatgt gtttttagtt cgttgagttt atccattctt caatccccta aagccttcag
1081 ctgttctttc atatgtggcc aacattttaa gtacagtgtt tgcttttata agtcggtgtt
1141 acttggatgt cctataaaat acccactttt tataaagatg atatttataa cctaggaact
1201 catgcctgtc ttggctgcag tccctgtaca tctaatatat actgatttgt ttgcccccag
1261 agaattttta aggtatctgc ctatatcgtg atcttttgaa atggtaaata aatctggtgc
1321 attaaaaatt aaaaaaaaaa aaaaaaaaa
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