LOCUS BC046632 3208 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens gremlin 2, cysteine knot superfamily, homolog (Xenopus
laevis), mRNA (cDNA clone MGC:44218 IMAGE:5288555), complete cds.
ACCESSION BC046632
VERSION BC046632.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3208)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3208)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (10-FEB-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 76 Row: e Column: 17
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 31377717.
FEATURES Location/Qualifiers
source 1..3208
/db_xref="H-InvDB:HIT000053048"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:44218 IMAGE:5288555"
/tissue_type="Brain, hypothalamus"
/clone_lib="NIH_MGC_96"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3208
/gene="GREM2"
/gene_synonym="CKTSF1B2"
/gene_synonym="DAND3"
/gene_synonym="PRDC"
/db_xref="GeneID:64388"
/db_xref="HGNC:HGNC:17655"
/db_xref="MIM:608832"
CDS 209..715
/gene="GREM2"
/gene_synonym="CKTSF1B2"
/gene_synonym="DAND3"
/gene_synonym="PRDC"
/codon_start=1
/product="gremlin 2, cysteine knot superfamily, homolog
(Xenopus laevis)"
/protein_id="AAH46632.1"
/db_xref="GeneID:64388"
/db_xref="HGNC:HGNC:17655"
/db_xref="MIM:608832"
/translation="MFWKLSLSLFMVAVLVKVAEARKNRPAGAIHSPYKDGSSNNSER
WQHQIKEVLASSQEALVVTERKYLKSDWCKTQPLRQTVSEEGCRSRTILNRFCYGQCN
SFYIPRHVKKEEESFQSCAFCKPQRVTSVLVELECPGLDPPFRLKKIQKVKQCRCMSV
NLSDSDKQ"
BASE COUNT 845 a 740 c 858 g 765 t
ORIGIN
1 agcgggctct cgcctctcct gcaccctcag ccggcgcgct tctcttatgg gcgtctgctg
61 cagtctggct gcggtcgaac tgaaagcggc ggcgggagac caaacttaga ccccgctgtg
121 gactagagaa ctcagagaag gcagagggag agggagagag agagagagaa gggacccgag
181 gaggaggctt ccatcacgtc attgcaggat gttctggaag ctttccctgt ccttgttcat
241 ggtggcggtg ctggtgaagg tggcggaagc ccggaagaac cggccggcgg gcgccatcca
301 ctcgccttac aaggacggca gcagcaacaa ctcggagaga tggcagcacc agatcaagga
361 ggtactggcc tccagccagg aggccctggt ggtcaccgag cgcaagtacc tcaagagtga
421 ctggtgcaag acgcagccgc tgcggcagac ggtgagcgag gagggctgcc ggagccgcac
481 catcctcaac cgcttctgct acggccagtg caactccttc tacatcccgc ggcacgtgaa
541 gaaggaggag gagtccttcc agtcctgcgc cttctgcaag ccccagcgcg tcacctccgt
601 cctcgtggag ctcgagtgcc ccggcctgga cccacccttc cgactcaaga aaatccagaa
661 ggtgaagcag tgccggtgca tgtccgtgaa cctgagcgac tcggacaagc agtgagcgcc
721 gggcaggacg cagctcagcc ccgcgcgcgc ccggcagctg ggtggcgccg ccgccgcctc
781 tgtccctgcc ctccgagccc actgtcacgc tgcctggtgt tccccatcag cagcaagcac
841 ttctcttagg gctgacggtg tccttgtcac agacgtggat cgcaagtgga gcttttgctg
901 atgtgttcct gaccgacccc gggtcccacc tgtgccccta aaccaggcgg tggatcaggc
961 ccgaaggaaa atgctggaaa accaccaccg ccaccgagca gtcagagagg acctttcgag
1021 gtgatgcact gtaaatccgg cattgatgtt tccgccatgt ggaaaagcaa ggatttccct
1081 ggccccgccc tgcactccag ctcgcccctt tcccgcgcga agtgaaggat gcgtcacttt
1141 tctgagcggc ccctcagacc tctcctgctg gtccctggac ctcttgctgg gagcgctcat
1201 tcttgtgact ggcaggctgc cctcggtcgc tgctgtgatg aggatatgtg caacctccat
1261 aaatatgtcg gtggacgggg cgtctcctaa taaacctgat accaagaaga caacttgagc
1321 cacttggatc ccgaagtggg cttcccggga aacctcgagc agagcaggct acacaatccc
1381 ccatcctcaa gtccccaccg cctcttcttc ctcactgtcc ccgcccccta tttgtggact
1441 aaagatgaac tctggtgtgc atgctattat tgctgcaatt agaatattat cacacacaaa
1501 ggtctctata ttaacgctgg ttttataagt gaccgtatat tgtaaagagc tgttaaaaag
1561 tattatagac ctattcatgt attatttcac atgttttgac tctggcttgc agcaccattc
1621 ggagtaagga tgacagcagg cccagaaggt gttttactca gaaaaaaaaa tgcctggtca
1681 gcaattcact gtcatgcacc tatttttaga ttgggcaggg agatgggagg agtcgtgatt
1741 tttactttga atactatttc actgacgtta ctaagtattg cagcacaatg tagaaattgg
1801 cttgggatgg ataggtatag ggaagggcat tcgttgggaa attgatgacc ggaaactaga
1861 aagcccctat aatgtggaat atgcatatgt ggggtgaaac cgtatactac tttcactgcc
1921 atgacactag gcaaaaaata tttcctgtta aaagaaagag aaaaagaaag ggatattgaa
1981 aaatataagg agttgagtcg ctttgtggta tagaagggag taaggaataa aagatataga
2041 atagtaatct agttgaactg ttctgcacaa aacatgcttc cttttcaaag aatagacttc
2101 aaaagggacg aacaaacatt aggtcacctt ttgtgtttat aatgaattgt tgacgtttcc
2161 atgctgtggt ctcttgatat acggaagtag acgtaactta ttttccagcg aaattatata
2221 cttcttctgg gctcctttgc tcagttgccc caggaaggct tccctgtgag taatgcttat
2281 ggaatctgac aaatgtgaat gagctgccat tggtgggaat cagtaaactt tgaaaacctt
2341 tcactgatga ttccctggta agtgctcctg tgaggggcca cttccctagt atgtgagaga
2401 gaccctctgc aagccgctgt ggggacttag cttcctgata ctaggtagtg atggtggatc
2461 tagagacatt cacttgaaga gcaaggattg gggtggggtg ggttggtgaa tctatctcag
2521 gccactgcac tgcaaggtgc atttctgtca tttctgcaac accatgagac ctgagcaaga
2581 atgtgctgtg gcagaggggg tcttggtttc ataaatgggt atatacagcc tgaactcagg
2641 aggcagaaat caaaagaaat ccttgagggc tggaacctga ggatagagcg aaaatggaga
2701 gaagggtgtt caaggtcagg agtgattttt gcatttggtg gaaaacctca agtcagactc
2761 agtggcagaa catgcagcag aaaagctgtg aaggaaggaa atttacgtga ttgtaatgga
2821 ggctaggggt ggattgggag gtgagtggag gagagtctct gaccagctgc aaagccaacc
2881 cctatcattt tattaacatg gaacccacac agatagggga gggattaagc taagaactta
2941 cagaatgcaa acacgagcac actctcttcg aacccaattg tgggtgtagc aatgaaagca
3001 atatgatatg ctgcagtgtg aagctccttc tggggttatc gtatgtacaa agtttacctt
3061 ataatggctc aaattgtatt taattttttt gttttgttta taaatgaaga aaagctataa
3121 gtataatgta attattttat aggtatacta ttaaattata gaacaaataa agataatcta
3181 ggattatatg cgaaaaaaaa aaaaaaaa
//