LOCUS BC046163 888 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens glutathione peroxidase 4 (phospholipid
hydroperoxidase), mRNA (cDNA clone MGC:57716 IMAGE:5742889),
complete cds.
ACCESSION BC046163
VERSION BC046163.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 888)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 888)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (31-JAN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 107 Row: i Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4504106.
FEATURES Location/Qualifiers
source 1..888
/db_xref="H-InvDB:HIT000098292"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:57716 IMAGE:5742889"
/tissue_type="Brain, adult medulla"
/clone_lib="NIH_MGC_119"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..888
/gene="GPX4"
/gene_synonym="MCSP"
/gene_synonym="PHGPx"
/gene_synonym="snGPx"
/gene_synonym="snPHGPx"
/db_xref="GeneID:2879"
/db_xref="HGNC:HGNC:4556"
/db_xref="MIM:138322"
CDS 15..608
/gene="GPX4"
/gene_synonym="MCSP"
/gene_synonym="PHGPx"
/gene_synonym="snGPx"
/gene_synonym="snPHGPx"
/codon_start=1
/transl_except=(pos:231..233,aa:OTHER)
/product="glutathione peroxidase 4 (phospholipid
hydroperoxidase)"
/protein_id="AAH46163.1"
/db_xref="GeneID:2879"
/db_xref="HGNC:HGNC:4556"
/db_xref="MIM:138322"
/translation="MSLGRLCRLLKPALLCGALAAPGLAGTMCASRDDWRCARSMHEF
SAKDIDGHMVNLDKYRGFVCIVTNVASQXGKTEVNYTQLVDLHVRYAECGLRILAFPC
NQFGKQEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGILGNA
IKWNFTKFLIDKNGCVVKRYGPMEEPLVIEKDLPHYF"
BASE COUNT 241 a 261 c 244 g 142 t
ORIGIN
1 ccagccccgc cgcgatgagc ctcggccgcc tttgccgcct actgaagccg gcgctgctct
61 gtggggctct ggccgcgcct ggcctggccg ggaccatgtg cgcgtcccgg gacgactggc
121 gctgtgcgcg ctccatgcac gagttttccg ccaaggacat cgacgggcac atggttaacc
181 tggacaagta ccggggcttc gtgtgcatcg tcaccaacgt ggcctcccag tgaggcaaga
241 ccgaagtaaa ctacactcag ctcgtcgacc tgcacgtccg atacgctgag tgtggtttgc
301 ggatcctggc cttcccgtgt aaccagttcg ggaagcagga gccagggagt aacgaagaga
361 tcaaagagtt cgccgcgggc tacaacgtca aattcgatat gttcagcaag atctgcgtga
421 acggggacga cgcccacccg ctgtggaagt ggatgaagat ccaacccaag ggcaagggca
481 tcctgggaaa tgccatcaag tggaacttca ccaagttcct catcgacaag aacggctgcg
541 tggtgaagcg ctacggaccc atggaggagc ccctggtgat agagaaggac ctgccccact
601 atttctagct ccacaagtgt gtggccccgc ccgagcccct gcccacgccc ttggagcctt
661 ccaccggcac tcatgacggc ctgcctgcaa acctgctggt ggggcagacc cgaaaatcca
721 gcgtgcaccc cgccggagga aggtcccatg gcctgctggg cttggctcgg cgcccccacc
781 cctggctacc ttgtgggaat aaacagacaa attagcaaaa aaaaaaaaaa aaaaaaaaaa
841 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//