LOCUS BC046126 1935 bp mRNA linear HUM 05-NOV-2003
DEFINITION Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member
3, mRNA (cDNA clone IMAGE:5212832), partial cds.
ACCESSION BC046126
VERSION BC046126.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1935)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1935)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (31-JAN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 107 Row: d Column: 9
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 9955969.
FEATURES Location/Qualifiers
source 1..1935
/db_xref="H-InvDB:HIT000098267"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:5212832"
/tissue_type="Blood, adult leukocytes"
/clone_lib="NIH_MGC_118"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..1935
/gene="ABCC3"
/gene_synonym="ABC31"
/gene_synonym="cMOAT2"
/gene_synonym="EST90757"
/gene_synonym="MLP2"
/gene_synonym="MOAT-D"
/gene_synonym="MRP3"
/db_xref="GeneID:8714"
/db_xref="MIM:604323"
CDS <1..1799
/gene="ABCC3"
/gene_synonym="ABC31"
/gene_synonym="cMOAT2"
/gene_synonym="EST90757"
/gene_synonym="MLP2"
/gene_synonym="MOAT-D"
/gene_synonym="MRP3"
/codon_start=3
/product="ABCC3 protein"
/protein_id="AAH46126.1"
/db_xref="GeneID:8714"
/db_xref="MIM:604323"
/translation="GGGSGARSARRWVRPRSPSLQPRLGPMDALCGSGELGSNFWDSN
LSVHTENPDLTPCFQNSLLAWVPCIYLWVALPCYLLYLRHHCRGYIILSHLSKLKMVL
GVLLWCVSWADLFYSFHGLVHGRAPAPVFFVTPLVVGVTMLLATLLIQYERLQGVQSS
GVLIIFWFLCVVCAIVPFRSKILLAKAEGEISDPFRFTTFYIHFALVLSALILACFRE
KPPFFSAKNVDPNPYPETSAGFLSRLFFWWFTKMAIYGYRHPLEEKDLWSLKEEDRSQ
MVVQQLLEAWRKQEKQTARHKASAAPGKNASGEDEVLLGARPRPRKPSFLKALLATFG
SSFLISACFKLIQDLLSFINPQLLSILIRFISNPMAPSWWGFLVAGLMFLCSMMQSLI
LQHYYHYIFVTGVKFRTGIMGVIYRKALVITNSVKRASTVGEIVNLMSVDAQRFMDLA
PFLNLLWSAPLQIILAIYFLWQNLGPSVLAGVAFMVLLIPLNGAVAVKMRAFQVKQMK
LKDSRIKLMSEILNGIKVLKLYAWEPSFLKQVEGIRQGELQLLRTAAYLHTTTTFTWM
CSPFLVRLGTGLGPCLQGSGCPGMARAHWTLP"
misc_feature 1011..1637
/gene="ABCC3"
/gene_synonym="ABC31"
/gene_synonym="cMOAT2"
/gene_synonym="EST90757"
/gene_synonym="MLP2"
/gene_synonym="MOAT-D"
/gene_synonym="MRP3"
/note="ABC_membrane; Region: ABC transporter transmembrane
region. This family represents a unit of six transmembrane
helices. Many members of the ABC transporter family
(pfam00005) have two such regions"
/db_xref="CDD:pfam00664"
BASE COUNT 376 a 617 c 502 g 440 t
ORIGIN
1 gcggaggcgg ctccggcgcc cgctctgccc gccgctgggt ccgaccgcgc tcgccttcct
61 tgcagccgcg cctcggcccc atggacgccc tgtgcggttc cggggagctc ggctccaact
121 tctgggactc caacctgtct gtgcacacag aaaacccgga cctcactccc tgcttccaga
181 actccctgct ggcctgggtg ccctgcatct acctgtgggt cgccctgccc tgctacttgc
241 tctacctgcg gcaccattgt cgtggctaca tcatcctctc ccacctgtcc aagctcaaga
301 tggtcctggg tgtcctgctg tggtgcgtct cctgggcgga ccttttttac tccttccatg
361 gcctggtcca tggccgggcc cctgcccctg ttttctttgt cacccccttg gtggtggggg
421 tcaccatgct gctggccacc ctgctgatac agtatgagcg gctgcagggc gtacagtctt
481 cgggggtcct cattatcttc tggttcctgt gtgtggtctg cgccatcgtc ccattccgct
541 ccaagatcct tttagccaag gcagagggtg agatctcaga ccccttccgc ttcaccacct
601 tctacatcca ctttgccctg gtactctctg ccctcatctt ggcctgcttc agggagaaac
661 ctccattttt ctccgcaaag aatgtcgacc ctaaccccta ccctgagacc agcgctggct
721 ttctctcccg cctgtttttc tggtggttca caaagatggc catctatggc taccggcatc
781 ccctggagga gaaggacctc tggtccctaa aggaagagga cagatcccag atggtggtgc
841 agcagctgct ggaggcatgg aggaagcagg aaaagcagac ggcacgacac aaggcttcag
901 cagcacctgg gaaaaatgcc tccggcgagg acgaggtgct gctgggtgcc cggcccaggc
961 cccggaagcc ctccttcctg aaggccctgc tggccacctt cggctccagc ttcctcatca
1021 gtgcctgctt caagcttatc caggacctgc tctccttcat caatccacag ctgctcagca
1081 tcctgatcag gtttatctcc aaccccatgg ccccctcctg gtggggcttc ctggtggctg
1141 ggctgatgtt cctgtgctcc atgatgcagt cgctgatctt acaacactat taccactaca
1201 tctttgtgac tggggtgaag tttcgtactg ggatcatggg tgtcatctac aggaaggctc
1261 tggttatcac caactcagtc aaacgtgcgt ccactgtggg ggaaattgtc aacctcatgt
1321 cagtggatgc ccagcgcttc atggaccttg cccccttcct caatctgctg tggtcagcac
1381 ccctgcagat catcctggcg atctacttcc tctggcagaa cctaggtccc tctgtcctgg
1441 ctggagtcgc tttcatggtc ttgctgattc cactcaacgg agctgtggcc gtgaagatgc
1501 gcgccttcca ggtaaagcaa atgaaattga aggactcgcg catcaagctg atgagtgaga
1561 tcctgaacgg catcaaggtg ctgaagctgt acgcctggga gcccagcttc ctgaagcagg
1621 tggagggcat caggcagggt gagctccagc tgctgcgcac ggcggcctac ctccacacca
1681 caaccacctt cacctggatg tgcagcccct tcctggtgag gcttggcaca gggctgggtc
1741 cctgcctcca gggctctggg tgcccaggca tggccagggc tcattggact ctaccctgac
1801 accacctcca cgctgctcag gtgaccctga tcaccctctg ggtgtacgtg tacgtggacc
1861 caaacaatgt gctggacgcc gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1921 aaaaaaaaaa aaaaa
//