LOCUS BC044659 5326 bp mRNA linear HUM 02-DEC-2006
DEFINITION Homo sapiens helicase-like transcription factor, mRNA (cDNA clone
MGC:47741 IMAGE:6015181), complete cds.
ACCESSION BC044659
VERSION BC044659.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5326)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 5326)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (17-JAN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 82 Row: m Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21071051.
FEATURES Location/Qualifiers
source 1..5326
/db_xref="H-InvDB:HIT000052891"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:47741 IMAGE:6015181"
/tissue_type="Testis, embryonal carcinoma"
/clone_lib="NIH_MGC_92"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..5326
/gene="HLTF"
/gene_synonym="HIP116"
/gene_synonym="HIP116A"
/gene_synonym="HLTF1"
/gene_synonym="RNF80"
/gene_synonym="ZBU1"
/db_xref="GeneID:6596"
/db_xref="HGNC:HGNC:11099"
/db_xref="MIM:603257"
CDS 187..3213
/gene="HLTF"
/gene_synonym="HIP116"
/gene_synonym="HIP116A"
/gene_synonym="HLTF1"
/gene_synonym="RNF80"
/gene_synonym="ZBU1"
/codon_start=1
/product="helicase-like transcription factor"
/protein_id="AAH44659.1"
/db_xref="GeneID:6596"
/db_xref="HGNC:HGNC:11099"
/db_xref="MIM:603257"
/translation="MSWMFKRDPVWKYLQTVQYGVHGNFPRLSYPTFFPRFEFQDVIP
PDDFLTSDEEVDSVLFGSLRGHVVGLRYYTGVVNNNEMVALQRDPNNPYDKNAIKVNN
VNGNQVGHLKKELAGALAYIMDNKLAQIEGVVPFGANNAFTMPLHMTFWGKEENRKAV
SDQLKKHGFKLGPAPKTLGFNLESGWGSGRAGPSYSMPVHAAVQMTTEQLKTEFDKLF
EDLKEDDKTHEMEPAEAIETPLLPHQKQALAWMVSRENSKELPPFWEQRNDLYYNTIT
NFSEKDRPENVHGGILADDMGLGKTLTAIAVILTNFHDGRPLPIERVKKNLLKKEYNV
NDDSMKLGGNNTSEKADGLSKDASRCSEQPSISDIKEKSKFRMSELSSSRPKRRKTAV
QYIESSDSEEIETSELPQKMKGKLKNVQSETKGRAKGSSKVIEDVAFACALTSSVPTT
KKKMLKKGACAVEGSKKTDVEERPRTTLIICPLSVLSNWIDQFGQHIKSDVHLNFYVY
YGPDRIREPALLSKQDIVLTTYNILTHDYGTKGDSPLHSIRWLRVILDEGHAIRNPNA
QQTKAVLDLESERRWVLTGTPIQNSLKDLWSLLSFLKLKPFIDREWWHRTIQRPVTMG
DEGGLRRLQSLIKNITLRRTKTSKIKGKPVLELPERKVFIQHITLSDEERKIYQSVKN
EGRATIGRYFNEGTVLAHYADVLGLLLRLRQICCHTYLLTNAVSSNGPSGNDTPEELR
KKLIRKMKLILSSGSDEECAICLDSLTVPVITHCAHVFCKPCICQVIQNEQPHAKCPL
CRNDIHEDNLLECPPEELARDSEKKSDMEWTSSSKINALMHALTDLRKKNPNIKSLVV
SQFTTFLSLIEIPLKASGFVFTRLDGSMAQKKRVESIQCFQNTEAGSPTIMLLSLKAG
GVGLNLSAASRVFLMDPAWNPAAEDQCFDRCHRLGQKQEVIITKFIVKDSVEENMLKI
QNKKRELAAGAFGTKKPNADEMKQAKINEIRTLIDL"
BASE COUNT 1790 a 867 c 1075 g 1594 t
ORIGIN
1 gaaggagacg gcgtcgacgt ctgactggac tcgcggcgac ttacctttca gtcgtgcgct
61 cctgatccgg cgctcggaat ttgtccccgg cttcagggct gcggggcctg gaaggaggcg
121 tatcgaggcg gctcgaaaac gatccagggg agccgaggcg ctcctcttgt catcccactc
181 agcgccatgt cctggatgtt caagagggat ccagtttgga agtacttgca gactgtccag
241 tatggagttc atggaaattt tccacgcctc tcatatccaa ctttctttcc acgttttgaa
301 ttccaagatg ttatccctcc agatgacttt ctaactagtg atgaagaagt agattccgtt
361 ttatttggaa gtttgagagg tcatgtggtt ggactacgct attacacggg agtagttaat
421 aataatgaaa tggttgcatt acaacgagat cctaataacc cttatgataa gaatgcaatt
481 aaagtaaaca atgtgaatgg aaatcaagtt ggccatttaa agaaagagct tgcaggtgct
541 ttggcctata tcatggacaa caaattggca caaattgaag gggtagttcc ttttggtgca
601 aacaatgctt ttaccatgcc tctgcatatg actttttggg gaaaagaaga aaatagaaaa
661 gcggtttcag atcagttgaa gaaacatgga tttaaattgg gtcctgcacc aaaaacttta
721 ggattcaatt tggaaagtgg ttggggctct ggaagagctg gaccaagcta tagtatgcca
781 gtgcatgctg cagtacagat gacaactgaa cagcttaaaa cagaatttga caaattgttt
841 gaagatttaa aagaagatga taaaacccat gaaatggaac cagctgaggc tattgaaaca
901 ccactgcttc cacatcaaaa acaagctcta gcttggatgg tgtcacggga aaatagcaaa
961 gaacttccac cattctggga acagcgaaat gacttatact ataacacaat aacaaatttt
1021 tctgagaagg accgaccaga aaatgtccat ggaggaattt tagctgatga tatgggtttg
1081 ggtaaaactc ttacagccat tgcagtaatc cttaccaact tccatgatgg cagacctctt
1141 cctattgaaa gagttaaaaa gaatctactg aagaaggaat ataatgttaa cgatgactct
1201 atgaaacttg gaggaaacaa taccagtgaa aaggcagatg gactaagcaa agacgcatct
1261 agatgtagtg aacaacccag tatttcagat atcaaggaga agagtaagtt tcgcatgtca
1321 gaattgtcta gctcccgccc caaaagaaga aaaactgctg tccagtacat agaaagcagt
1381 gattcagagg aaattgaaac aagtgaattg ccgcagaaaa tgaaaggcaa actgaaaaat
1441 gtacagtctg aaactaaagg cagggcgaaa ggatcttcta aggttataga agatgtggca
1501 tttgcatgtg cattaacttc atctgttcct acaacaaaaa agaaaatgtt gaaaaaggga
1561 gcttgtgcag tggaggggtc aaagaaaact gatgttgagg agagaccaag aacaacactg
1621 atcatctgtc cgctttctgt gttaagcaac tggattgacc agtttggaca acatataaaa
1681 tcagatgtac acttgaattt ttatgtttat tatggtcctg atcgtattag agaaccggcc
1741 ttactttcaa aacaggatat tgttttgact acgtataata ttttaactca tgactatgga
1801 actaaaggag atagtccatt acatagcata aggtggctaa gagtgatcct ggatgaagga
1861 catgccatac gaaatccaaa tgctcagcag acaaaagctg tacttgactt agaatcagaa
1921 agaagatggg ttttgacagg tactccaatc cagaattctt taaaggactt gtggtctctt
1981 ctttcctttt taaaacttaa accatttatt gatagagaat ggtggcatag aacaatacag
2041 cgtcctgtca caatgggaga tgaaggagga cttaggcgtt tacagtccct aattaaaaat
2101 attacactta gaagaacaaa gacaagcaaa attaaaggaa aacctgtttt ggagttacca
2161 gaacgtaaag tatttattca gcacattaca ctttcagatg aagagagaaa gatttatcag
2221 tctgtgaaaa atgaaggcag agccactatt ggaaggtatt ttaatgaagg gactgtcctg
2281 gcacattatg cagatgtcct gggtcttttg cttagactgc ggcaaatttg ttgccatact
2341 taccttctta caaatgcagt gtcttccaat ggcccctcag gaaatgatac acctgaagaa
2401 ctgagaaaga agttaataag gaagatgaag ttaattctga gctcaggttc agatgaggaa
2461 tgtgcaattt gcctggattc tttaacagtt cctgtgataa cacattgtgc acatgtattt
2521 tgtaaaccct gtatttgcca agtcattcag aatgagcagc cacatgctaa atgcccttta
2581 tgcagaaatg atatacatga agataattta ttagaatgtc ctccagaaga attagcacgt
2641 gacagtgaga aaaagtctga tatggaatgg acatccagtt caaagattaa tgcgctaatg
2701 cacgcattga ctgacttaag aaagaagaat cccaacataa aaagtttggt tgtttctcag
2761 tttacaacat tcctgtcttt aatagaaata ccacttaaag cctctggatt tgtgtttact
2821 cgtttggatg gttccatggc ccaaaagaaa agagttgaat caattcagtg ttttcaaaac
2881 actgaagcag gatctccaac tataatgctt ctgtccttaa aagcaggtgg agttggtttg
2941 aatctgtctg cagcttctcg agtgttttta atggatccag cctggaatcc tgctgctgaa
3001 gatcagtgct ttgacagatg ccatagactt ggtcagaagc aagaagttat catcacaaaa
3061 ttcattgtaa aggactctgt tgaagaaaat atgctgaaaa tacaaaacaa aaagagagaa
3121 cttgcagcag gagcctttgg aactaaaaaa ccaaatgctg acgaaatgaa acaagccaaa
3181 attaatgaaa tcagaacatt aattgactta taatttgtgg gattttagta aggtcagttt
3241 gattggatac ttaagtttta gaaatgagaa aaatacagag ttttagaaat gagatctaga
3301 gaacacgtct tctaaaaggg gcatatttta tattagtgaa gaggtattac tgacacaatt
3361 tcttctatat atgaacctat ttttaatgaa acttcaaata gcaataagtt ccgttatata
3421 ctgtggcctg aaataatttg agaaaaaagg ttactttgtt attcagcttt tcataatatc
3481 tatgctgagt attttcacgt atcttccaag tactcagctt tttcgtattt caaataaggt
3541 cagacctttt atacttttga ccaaatagtt attttctatg ttggacactt agttatttgc
3601 caaagcctcc gatttgtgat gcagtgtttg tagtccttgt aaacaatata tacagactat
3661 acaagaatta attttattgg gctttcaaaa accatatttg cattccagaa ccaaatctta
3721 aatgagacca aagtccaggt tagcacaggt ttttattttt cctacagcta cattgagata
3781 tagttcacat aaatgacttg gagttttatg ttcatgaaaa aattagggat tatgttaaga
3841 gtactatttt ttccatttta gttaagtagt actacactca ttgtttaaat gtaacttgct
3901 gtgtctgagg tataaatata gtctgtggga gtgagaggca aaccagtcct acccaatttg
3961 atttgaatat tttaaattat ggaactgcta aatagatatt tctataaata gataattttt
4021 atttatgtag ctttttttgg aagtaacttt ataaattttt ataattcaga agactactat
4081 atgtgagagg cgtgatatct ggatggaagt tgggctggat gatctccaaa gtcgtttcaa
4141 ctcttaaaga catcttaatc ctgaatgtaa acaattgtta tgtgtttaga atcagaattt
4201 gattttgaac ttgagtaatt catccttaca gctatctgta gaattagtca tcttttttct
4261 tttctttttt ttttactttt ttgttaataa gcaaacttat ttgctgcaga atttgggttg
4321 actcctgagc atatttaaaa caaagaagct agaaatttag cagtcagatt aggtaggtgg
4381 ttttatttca aagggaaact ttaatccaaa gaaagattaa ttactctaac aaacaagaga
4441 agcttcatgt ttgatgatac agatttaaga atacctgaga cttaagagtg ttggaagtca
4501 tttgatagaa agatgagatc ggagacaatg ttgtgttata gggcacacat tgaaggtata
4561 tgccaaatct ctcaccagat aagtcctttt ctccctgtgc cgttttcttg ctcaaaggga
4621 acagtgaatt agccagctag aatcttcctg gtcccttttt gaggcagtag caggtaagga
4681 aagggctgat tttcatcaaa accaagacct ttctgcaggg atgatagtgg aataataatg
4741 tgggattagc ccgctagcat taggagcagt tgggaagtta cctggtagat caagcattac
4801 acacaaaaaa tcaagttgat cagagtatgg gttctccata tagcaatact tcagtgagat
4861 taagtataaa cagtttttgg caaaaaacaa cacagtctac tctttctgct tacaaagaca
4921 aagccttaca aactcactat gaaggtaaag ggaggacagc ttgcttcttt gcccagacat
4981 ttacaaagtt gtttttaaaa cacactcata agtaagtttg gcaagttgtt taaaaaatgt
5041 ctctttgttt tgtacagttc tgttagatgt tgttatattt taaaagttta atttaaaaaa
5101 tttaatttgt ccttcctaag aaggataaat atataaaaaa gccactggaa tgaaaacttc
5161 ctatatgcta tgctgttgtc ttattattat atagaaaaat aactttagaa aaatattgaa
5221 gacattgtat taccacttgt gattcaaaca attttgtggt taaaactgga ttttaaattt
5281 aaaaatcaat aaaaatttca aatgttaaaa aaaaaaaaaa aaaaaa
//