LOCUS BC043564 2022 bp mRNA linear HUM 03-JAN-2005
DEFINITION Homo sapiens potassium voltage-gated channel, shaker-related
subfamily, member 2, mRNA (cDNA clone MGC:50217 IMAGE:5212949),
complete cds.
ACCESSION BC043564
VERSION BC043564.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2022)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2022)
AUTHORS Director MGC Project.
TITLE Direct Submission
JOURNAL Submitted (09-JAN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steve Jones, Sarah Barber, Mabel Brown-John, Yaron Butterfield,
Andy Chan, Steve S. Chand, William Chow, Alison Cloutier, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Amara Masson, Mike R. Mayo, Josh Moran, Ryan Morin,
Teika Olson, Diana Palmquist, Anca Petrescu, Anna Liisa Prahbu,
Parvaneh Saeedi, JR Santos, Angelique Schnerch, Ursula Skalska,
Duane Smailus, Jeff Stott, Miranda Tsai, George Yang, Jacquie
Schein, Asim Siddiqui, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 87 Row: k Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 25952079.
FEATURES Location/Qualifiers
source 1..2022
/db_xref="H-InvDB:HIT000052832"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:50217 IMAGE:5212949"
/tissue_type="Blood, adult leukocytes"
/clone_lib="NIH_MGC_118"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2022
/gene="KCNA2"
/gene_synonym="HBK5"
/gene_synonym="HK4"
/gene_synonym="HUKIV"
/gene_synonym="KV1.2"
/gene_synonym="MK2"
/gene_synonym="NGK1"
/gene_synonym="RBK2"
/db_xref="GeneID:3737"
/db_xref="MIM:176262"
CDS 576..1646
/gene="KCNA2"
/gene_synonym="HBK5"
/gene_synonym="HK4"
/gene_synonym="HUKIV"
/gene_synonym="KV1.2"
/gene_synonym="MK2"
/gene_synonym="NGK1"
/gene_synonym="RBK2"
/codon_start=1
/product="KCNA2 protein"
/protein_id="AAH43564.1"
/db_xref="GeneID:3737"
/db_xref="MIM:176262"
/translation="MTVATGDPADEAAALPGHPQDTYDPEADHECCERVVINISGLRF
ETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPV
NVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSG
PARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSF
TDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAE
KPEDAQQGQQAMSLAILRVIRLERRPLQSQKSKRGRQHLNTSHDCTLGINLVAGMTVQ
WTRASGPDDRQTPAVTTLHRMY"
BASE COUNT 540 a 527 c 475 g 480 t
ORIGIN
1 ggcacataga agagtgagcc atcatctggt ttccagcgcc aagacttctg caggagagcc
61 tccgctgggc tttcaagttg gcaacgtcac acctcctgag gacagccagg actccagctt
121 ttgctgagct ttgcatcttg cctccttcct tcaaaaggct ccaggcccat gctcggctgt
181 cttcaagtcc cgcatgcccc tggccaggca cctcaccgcc cctccagccc agcccaatcc
241 tagagctcac ctccaggacc cagagtctgc ccttctgccc agaatgactc accattattt
301 ctagctcgag tgagaagacg tgatgaggag ttgggctgcc tgttggtgca tctcagattc
361 ctgcagcatc tgatcagctc tgcaaggaag agagcttcac gtctctggtc agccaagcga
421 ggctgtctct ccagctctca gagagctctc ggggctctcc tgcaggagac caggccaatg
481 ctcctgtgct tcctggggcc agtagcagca ccctgagctc cctgccacca ggcagctgaa
541 aggcatagcg tgaggtgctt ctctcagtcc caattatgac agtggccacc ggagacccag
601 cagacgaggc tgctgccctc cctgggcacc cacaggacac ctatgaccca gaggcagacc
661 acgagtgctg tgagagggtg gtgatcaaca tctcagggct gcggtttgag acccagctaa
721 agaccttagc ccagtttcca gagaccctct taggggaccc aaagaaacga atgaggtact
781 ttgaccccct ccggaatgag tactttttcg atcggaaccg ccctagcttt gatgccattt
841 tgtactacta ccagtcaggg ggccgattga ggcgacctgt gaatgtgccc ttagatatat
901 tctctgaaga aattcggttt tatgagctgg gagaagaagc gatggagatg tttcgggaag
961 atgaaggcta catcaaggag gaagagcgtc ctctgcctga aaatgagttt cagagacaag
1021 tgtggcttct ctttgaatac ccagagagct cagggcctgc caggattata gctattgtgt
1081 ctgtcatggt gattctgatc tcaattgtca gcttctgtct ggaaacattg cccatcttcc
1141 gggatgagaa tgaagacatg catggtagtg gggtgacctt ccacacctat tccaacagca
1201 ccatcgggta ccagcagtcc acttccttca cagacccttt cttcattgta gagacactct
1261 gcatcatctg gttctccttt gaattcttgg tgaggttctt tgcctgtccc agcaaagccg
1321 gcttcttcac caacatcatg aacatcattg acattgtggc catcatcccc tacttcatca
1381 ccctggggac agagttggct gagaagccag aggacgctca gcaaggccag caggccatgt
1441 cactggccat cctccgtgtc atccggttgg aacgcagacc tctgcaaagc cagaagagta
1501 agcggggaag gcagcatctg aacacctcac atgactgcac cttaggaatt aacctagtcg
1561 cgggcatgac tgtacagtgg accagggcat ctggtcctga tgacaggcag acaccagctg
1621 taactacatt gcacaggatg tattgatatt atcattcttg ctgacatatt ctggaagctt
1681 tcagccccac caacactgcc ccacccagga cttctgcagc tgagagttcc tgtgtcagta
1741 gggtctgata tttgtacata ggttatacat atatgtgtac atatgtgcct caatgaacat
1801 tgcctgtcca cctgatcatg ggtgtacata gacttcatag agctccacag tcttttgtaa
1861 atattgacac aagtaaataa gtatataaat atatattact ggggatttat tttaacatca
1921 ttctgtgtga tatgaaaaaa ataaaatttt tgacagacaa aaaaaaaaaa aaaaaaaaaa
1981 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa
//