LOCUS BC043495 3168 bp mRNA linear HUM 21-OCT-2003
DEFINITION Homo sapiens PAS domain containing serine/threonine kinase, mRNA
(cDNA clone IMAGE:5492340), partial cds.
ACCESSION BC043495
VERSION BC043495.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3168)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3168)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (09-JAN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steven Jones, Jennifer Asano, Ian Bosdet, Yaron Butterfield,
Susanna Chan, Readman Chiu, Chris Fjell, Erin Garland, Ran Guin,
Letticia Hsiao, Martin Krzywinski, Reta Kutsche, Oliver Lee, Soo
Sen Lee, Victor Ling, Carrie Mathewson, Candice McLeavy, Steven
Ness, Pawan Pandoh, Anna-Liisa Prabhu, Parvaneh Saeedi, Jacqueline
Schein, Duane Smailus, Michael Smith, Lorraine Spence, Jeff Stott,
Michael Thorne, Miranada Tsai, Natasja van den Bosch, Jill Vardy,
George Yang, Scott Zuyderduyn, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 89 Row: d Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 8923825.
FEATURES Location/Qualifiers
source 1..3168
/db_xref="H-InvDB:HIT000097699"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:5492340"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..3168
/gene="PASK"
/gene_synonym="DKFZP434O051"
/gene_synonym="KIAA0135"
/gene_synonym="PASKIN"
/gene_synonym="STK37"
/db_xref="GeneID:23178"
/db_xref="MIM:607505"
CDS <1..2862
/gene="PASK"
/gene_synonym="DKFZP434O051"
/gene_synonym="KIAA0135"
/gene_synonym="PASKIN"
/gene_synonym="STK37"
/codon_start=1
/product="PASK protein"
/protein_id="AAH43495.1"
/db_xref="GeneID:23178"
/db_xref="MIM:607505"
/translation="YGKTELLGKNITFLIPGFYSYMDLAYNSSLQLPDLASCLDVGNE
SGCGERTLDPWQGQDPAEGGQDPRINVVLAGGHVVPRDEIRKLMESQDIFTGTQTELI
AGGQLLSCLSPQPAPGVDNVPEGSLPVHGEQALPKDQQITALGREEPVAIESPGQDLL
GESRSEPVDVKPFASCEDSEAPVPAEDGGSDAGMCGLCQKAQLERMGVSGPSGSDLWA
GAAVAKPQAKGQLAGGSLLMHCPCYGSEWGLWWRSQDLAPSPSGMAGLSFGTPTLDEP
WLGVENDREELQTCLIKEQLSQLSLAGALDVPHAELVPTECQAVTAPVSSCDLGGRDL
CGGCTGSSSACYALATDLPGGLEAVEAQEVDVNSFSWNLKELFFSDQTDQTSSNCSCA
TSELRETPSSLAVGSDPDVGSLQEQGSCVLDDRELLLLTGTCVDLGQGRRFRESCVGH
DPTEPLEVCLVSSEHYAASDRESPGHVPSTLDAGPEDTCPSAEEPRLNVQVTSTPVIV
MRGAAGLQREIQEGAYSGSCYHRDGLRLSIQFEVRRVELQGPTPLFCCWLVKDLLHSQ
RDSAARTRLFLASLPGSTHSTAAELTGPSLVEVLRARPWFEEPPKAVELEGLAACEGE
YSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLE
IAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFR
QLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEY
CAPEVLMGNPYRGPELEMWSLGVTLYTLVFEENPFCELEETVEAAIHPPYLVSKELMS
LVSGLLQPVPERRTTLEKLVTDPWVTQPVNLADYTWEEVFRVNKPESGVLSAASLEMG
NRSLSDVAQAQELCGGPVPGEAPNGQGCLHPGDPRLLTS"
misc_feature 1885..2643
/gene="PASK"
/gene_synonym="DKFZP434O051"
/gene_synonym="KIAA0135"
/gene_synonym="PASKIN"
/gene_synonym="STK37"
/note="S_TKc; Region: Serine/Threonine protein kinases,
catalytic domain"
/db_xref="CDD:smart00220"
BASE COUNT 727 a 812 c 939 g 690 t
ORIGIN
1 tacggaaaga cggagctcct gggcaagaat atcactttcc tgattcctgg tttctacagc
61 tacatggacc ttgcgtacaa cagctcatta cagctcccag acctggccag ctgcctggac
121 gtcggcaatg agagtgggtg tggggagaga accttggacc cgtggcaggg ccaggaccca
181 gctgaggggg gccaggatcc aaggattaat gtcgtgcttg ctggtggcca cgttgtgccc
241 cgagatgaga tccggaagct gatggaaagc caagacatct tcactgggac tcagactgag
301 ctgattgctg gaggccagct cctttcctgc ctctcacctc agcctgctcc aggggtggac
361 aatgtcccag aaggaagcct gccagtgcac ggtgaacagg cgctgcccaa ggaccagcaa
421 atcactgcct tggggagaga ggaacctgtg gcaatagaga gccccggaca ggatcttctg
481 ggagaaagca ggtctgaacc agtggatgtg aagccatttg cttcctgcga agattctgaa
541 gctccagtcc cagctgagga tgggggcagt gatgctggca tgtgtggcct gtgtcagaag
601 gcccagctag agcggatggg agtcagtggt cccagcggtt cagacctttg ggctggggct
661 gccgtggcca agccccaggc caagggtcag ctggcggggg gcagcctcct gatgcactgc
721 ccttgctatg ggagtgaatg gggcttgtgg tggcgaagcc aggacttggc ccccagcccc
781 tctgggatgg caggcctctc gtttgggaca cctactctag atgagccgtg gctgggagtg
841 gaaaacgacc gagaagagct gcagacctgc ttgattaagg agcagctgtc ccagttgagc
901 cttgcgggag ccctggatgt cccccacgcc gaactcgttc cgacagagtg ccaggctgtc
961 accgctcctg tgtcgtcctg cgatctggga ggcagagacc tgtgcggtgg ctgcacgggc
1021 agctcctcag cctgctatgc cttggccacg gacctccctg ggggcctgga agcagtggag
1081 gcccaggagg ttgatgtgaa ttcgttttcc tggaacctca aggaactctt tttcagtgac
1141 cagacagacc aaacgtcatc aaattgttcc tgtgctacgt ctgaactcag agagacaccc
1201 tcttccttgg cagtgggctc cgatccagat gtaggcagtc tccaggaaca ggggtcgtgt
1261 gtcctggatg acagggagct gttactactg accggcacct gtgttgacct tggccaaggc
1321 cgacggttcc gggagagctg tgtgggacat gatccaacag aaccgcttga ggtttgtttg
1381 gtgtcctctg agcattatgc agcaagcgac agagaaagcc caggacacgt tccttccacg
1441 ttggatgctg gccctgagga cacgtgccca tcagcagagg agccaaggct gaacgtccag
1501 gtcacctcca cgcccgtgat cgtgatgcgc ggggctgctg gcctgcagcg ggagatccag
1561 gagggtgcct actccgggag ctgctaccat cgagatggct tacggctgag tatacagttt
1621 gaggtgaggc gggtggagct ccagggcccc acacctctgt tctgctgctg gctggtgaaa
1681 gacctcctcc acagccaacg cgactcagcc gccaggaccc gcctgttcct tgccagcctg
1741 cccggctcca cccactctac cgctgctgag ctcaccggac ccagcctggt ggaagtgctc
1801 agagccagac cctggtttga ggagcccccc aaggctgtgg aactggaggg gttggcggcc
1861 tgtgagggcg agtactccca aaagtacagt accatgagcc cgctgggcag tggggccttc
1921 ggcttcgtgt ggactgctgt ggacaaggaa aaaaacaagg aggtggtggt gaagtttatt
1981 aagaaggaga aggtcttgga ggattgttgg attgaggatc ccaaacttgg gaaagttact
2041 ttagagatcg caattctatc cagggtggag cacgccaata tcatcaaggt attggatata
2101 tttgaaaacc aagggttctt ccagcttgtg atggagaagc acggctccgg cctagacctc
2161 ttcgctttca tcgaccgcca ccccaggctg gatgagcccc tggcgagcta catcttccga
2221 caactagtgt cagcagtggg atacctgcgc ttgaaggaca tcatccaccg tgacatcaag
2281 gatgagaaca tcgtgatcgc cgaggacttc acaatcaagc tgatagactt tggctcggcc
2341 gcctacttgg aaaggggaaa attattttat actttttgtg ggaccatcga gtactgtgca
2401 ccggaagttc tcatggggaa tccctacaga gggccggagc tggagatgtg gtctctggga
2461 gtcactctgt acacgctggt ctttgaggag aaccccttct gtgagctgga ggagaccgtg
2521 gaggctgcca tacacccgcc atacctggtg tccaaagaac tcatgagcct tgtgtctggg
2581 ctgctgcagc cagtccctga gagacgcacc accttggaga agctggtgac agacccgtgg
2641 gtaacacagc ctgtgaatct tgctgactat acatgggaag aggtgtttcg agtaaacaag
2701 ccagaaagtg gagttctgtc cgctgcgagc ctggagatgg ggaacaggag cctgagtgat
2761 gtggcccagg ctcaggagct ttgtgggggc cccgttccag gcgaggctcc taatggccaa
2821 ggctgtttgc atcccgggga tccccgtctg ctgaccagct aaacaccaat ttcttcctgc
2881 ttttctccac ttggtttgga aaatcacaca gttttcaggc tccatctgtt tggagaaaat
2941 acattctgaa gcatccccaa ttcaccttct aaaaactcat gtgcaggttt gataaacacc
3001 agaacagaag acagtgatgc tgtattattt tagatttatt acatagattt ggaattcact
3061 tttttcatga cctagaaaaa aacattccag tgttcaactg ttttatatta ttaaagggct
3121 tttaatttgt gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//