LOCUS BC042577 1769 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens caspase 8 associated protein 2, mRNA (cDNA clone
IMAGE:4749460), partial cds.
ACCESSION BC042577
VERSION BC042577.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1769)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1769)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-JAN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: James Cleaver, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 29 Row: k Column: 3.
FEATURES Location/Qualifiers
source 1..1769
/db_xref="H-InvDB:HIT000097289"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4749460"
/tissue_type="Skin, squamous cell carcinoma"
/clone_lib="NCI_CGAP_Skn4"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6.1"
gene <1..1769
/gene="CASP8AP2"
/gene_synonym="CED-4"
/gene_synonym="FLASH"
/gene_synonym="RIP25"
/db_xref="GeneID:9994"
/db_xref="HGNC:HGNC:1510"
/db_xref="MIM:606880"
CDS <1..1109
/gene="CASP8AP2"
/gene_synonym="CED-4"
/gene_synonym="FLASH"
/gene_synonym="RIP25"
/codon_start=3
/product="CASP8AP2 protein"
/protein_id="AAH42577.1"
/db_xref="GeneID:9994"
/db_xref="HGNC:HGNC:1510"
/db_xref="MIM:606880"
/translation="QSSMIQTQVPDIYEFLKDASDKMGHSDEVADECFKLHQVWETKV
PESIEELPSMEEISHSVGEHLPNTYVDLTKDPVTETKNLGEFIEVTVLHIDQLGCSGG
NLNQSAQILDNSLQADTVGAFIDLTQDASSEAKSEGNHPALAVEDLGCGVIQVDEDNC
KEEKAQVANRPLKCIVEETYIDLTTESPSSCEVKKDELKSEPGSNCDNSELPGTLHNS
HKKRRNISDLNHPHKKQRKETDLTNKEKTKKPTQDSCENTEAHQKKASKKKAPPVTKD
PSSLKATPGIKDSSAALATSTSLSAKNVIKKKGEIIILWTRNDDREILLECQKRGPSF
KTFAYLAAKLDKNPNQVSERFQQLMKLFEKSKCR"
BASE COUNT 640 a 268 c 325 g 536 t
ORIGIN
1 aacagagctc tatgatacaa acacaggttc ctgatatata tgaatttctt aaagatgctt
61 cagataagat gggtcatagt gatgaagtgg ctgatgaatg tttcaaattg catcaagtat
121 gggaaacaaa agtgcctgaa agcattgaag aattgccttc aatggaagaa atctcacact
181 ctgttgggga acatcttcca aacacatacg tagatctaac gaaagatcca gtcactgaaa
241 ccaaaaactt gggggaattc atagaagtaa cagttttaca tattgatcag ttgggatgtt
301 ctggaggcaa tttaaatcag agtgctcaaa tattagacaa ttctttgcag gctgatactg
361 taggtgcttt tattgatttg acacaagatg cttcaagtga ggctaaaagt gaaggtaatc
421 atcctgcatt agctgtggaa gacttgggat gtggggtgat acaggtagat gaagataatt
481 gtaaggaaga aaaggcacaa gtggcaaaca ggcctttaaa atgcattgtt gaggaaacct
541 atatcgactt gaccacagaa tctcccagtt catgtgaagt aaaaaaagat gagttaaaat
601 cagagccagg atcaaattgt gataactcgg agttgcctgg gactttgcat aattctcaca
661 aaaagagaag aaacatttct gatctaaatc atcctcataa aaaacaaaga aaggaaacag
721 acttaactaa taaggaaaag accaagaaac ctacccaaga ttcttgtgag aatactgaag
781 ctcaccaaaa gaaagccagt aagaagaagg cccctcctgt gactaaagat ccctcatcat
841 taaaggcaac cccagggatt aaggattcat cagcagcact tgccacttct acaagtcttt
901 ctgcaaaaaa tgttattaaa aagaagggag aaattatcat tttatggaca agaaatgatg
961 accgggaaat tttattggag tgtcagaaaa gagggccatc atttaaaaca tttgcatatt
1021 tagccgccaa gttggataaa aatccaaatc aggtctcaga aagattccag cagctaatga
1081 agctctttga aaagtcaaaa tgcagataag ttgctgaatt cctgggactc ttaactgata
1141 ttgcatacta cacagaagct tcaaattcct catgttttaa atgagcacta gagggaggtt
1201 tatcaccttt ttggttacca gatgataatc tatatttgtt attactcagt gactctctaa
1261 tttcacatca gcatgttcag cttgtgctag tcatcattct gatttgctta tctgtttttg
1321 gtcaaaatat ttatttttaa acatgttaga acttaccaaa atgaaagcaa cagtgatgta
1381 ttgaaatctt agttttgata ttttaaagaa atgactttct agattaaaaa aatagttttg
1441 tagcatttta aacttagtga ctatttagtt caattgttca tccatttttt atttgctttt
1501 ataattgcct ccttgttttg gtatattgta aaataattta aataatgtat ttataaatat
1561 gtataattat gatgtaaaat accgtgtgta tatgtatgta tgtgtgtttc tgtatatgca
1621 cacacataaa cggctttgcc tagccaagga ttttttttat ctgtataaaa ctttttgtat
1681 aaagtttgct ttcaataaca gtaatgtata ataaaaccat gtaaagtttt gttgtaaaaa
1741 aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
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