LOCUS BC042482 1211 bp mRNA linear HUM 04-NOV-2003
DEFINITION Homo sapiens potassium channel tetramerisation domain containing 7,
mRNA (cDNA clone MGC:34731 IMAGE:5165722), complete cds.
ACCESSION BC042482
VERSION BC042482.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1211)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1211)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (02-JAN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 52 Row: l Column: 6
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis, GenomeScan gene prediction.
FEATURES Location/Qualifiers
source 1..1211
/db_xref="H-InvDB:HIT000052698"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:34731 IMAGE:5165722"
/tissue_type="Brain, adult medulla"
/clone_lib="NIH_MGC_119"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1211
/gene="KCTD7"
/gene_synonym="FLJ32069"
/db_xref="GeneID:154881"
CDS 123..989
/gene="KCTD7"
/gene_synonym="FLJ32069"
/codon_start=1
/product="KCTD7 protein"
/protein_id="AAH42482.1"
/db_xref="GeneID:154881"
/translation="MVVVTGREPDSRRQDGAMSSSDAEDDFLEPATPTATQAGHALPL
LPQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGT
HFGDVLNFLRSGDLPPRERVRAVYKEAQYYAIGPLLEQLENMQPLKGEKVRQAFLGLM
PYYKDHLERIVEIARLRAVQRKARFAKLKVCVFKEEMPITPYECPLLNSLRFERSESD
GQLFEHHCEVDVSFGPWEAVADVYDLLHCLVTDLSAQGLTVDHQCIGVCDKHLVNHYY
CKRPIYEFKITW"
misc_feature 279..536
/gene="KCTD7"
/gene_synonym="FLJ32069"
/note="K_tetra; Region: K+ channel tetramerisation domain.
The N-terminal, cytoplasmic tetramerisation domain (T1) of
voltage-gated K+ channels encodes molecular determinants
for subfamily-specific assembly of alpha-subunits into
functional tetrameric channels. It is distantly related to
the BTB/POZ domain pfam00651"
/db_xref="CDD:pfam02214"
BASE COUNT 281 a 356 c 339 g 235 t
ORIGIN
1 cgcccccctc cggccagccc gcagccggcc gcgtcatgcc aggcgctgct cggcggtagg
61 gagtgcccgg ggccgccgcc tccgcccgcc cgaagccgcg cccactgccc agagccagag
121 ggatggtggt agtcacgggg cgggagccag acagccgtcg tcaggacggt gccatgtcca
181 gctctgacgc cgaagacgac tttctggagc cggccacgcc gacggccacg caggcggggc
241 acgcgctgcc cctgctgcca caggagtttc ctgaggttgt tccccttaac atcggagggg
301 ctcacttcac tacacgcctg tccacactgc ggtgctacga agacaccatg ttggcagcca
361 tgttcagtgg gcggcactac atccccacgg actccgaggg ccggtacttc atcgaccgag
421 atggcacaca ctttggagat gtgctgaatt tcctgcgctc aggggacctc ccacccaggg
481 agcgtgttcg agctgtgtac aaagaggccc agtactatgc catcgggccc ctcctggagc
541 agctggagaa catgcagcca ctgaagggcg agaaggtgcg ccaagcgttt ctgggactca
601 tgccctatta caaagaccac ttggagcgga ttgtggagat cgcccggctg cgtgcggtcc
661 agcggaaggc ccgctttgcc aagctcaagg tctgtgtctt caaggaggag atgcccatca
721 ccccctatga gtgtccgctc ctcaactccc tgcgatttga gcggagtgag agtgacgggc
781 agctttttga gcaccactgt gaagtggatg tgtcttttgg gccctgggag gctgtggctg
841 atgtttatga cctgctgcac tgcctggtca cggacctctc ggcccagggt ctcaccgtgg
901 accaccagtg catcggggtg tgtgacaagc acctcgtgaa ccactactac tgcaagcgcc
961 ccatctatga gttcaagatc acatggtgaa attgaaaaag atccccaagg atctgttact
1021 actgcatttc cttcttgctc tgtctacagc ctaggccaac tagtcagggt ctggacatgc
1081 atctcctaaa ggaagaactg tgtagcacca ttgatcacaa tgtaacattt ccatgctgca
1141 ttaagggtgt ctctctctaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1201 aaaaaaaaaa a
//