LOCUS BC042458 3234 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens pleckstrin homology domain containing, family A
(phosphoinositide binding specific) member 1, mRNA (cDNA clone
MGC:42747 IMAGE:4828008), complete cds.
ACCESSION BC042458
VERSION BC042458.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3234)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3234)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-JAN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 72 Row: c Column: 15.
FEATURES Location/Qualifiers
source 1..3234
/db_xref="H-InvDB:HIT000052695"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:42747 IMAGE:4828008"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3234
/gene="PLEKHA1"
/gene_synonym="TAPP1"
/db_xref="GeneID:59338"
/db_xref="HGNC:HGNC:14335"
/db_xref="MIM:607772"
CDS 1465..2679
/gene="PLEKHA1"
/gene_synonym="TAPP1"
/codon_start=1
/product="pleckstrin homology domain containing, family A
(phosphoinositide binding specific) member 1"
/protein_id="AAH42458.1"
/db_xref="GeneID:59338"
/db_xref="HGNC:HGNC:14335"
/db_xref="MIM:607772"
/translation="MPYVDRQNRICGFLDIEENENSGKFLRRYFILDTREDSFVWYMD
NPQNLPSGSSRVGAIKLTYISKVSDATKLRPKAEFCFVMNAGMRKYFLQANDQQDLVE
WVNVLNKAIKITVPKQSDSQPNSDNLSRHGECGKKQVSYRTDIVGGVPIITPTQKEEV
NECGESIDRNNLKRSQSHLPYFTPKPPQDSAVIKAGYCVKQGAVMKNWKRRYFQLDEN
TIGYFKSELEKEPLRVIPLKEVHKVQECKQSDIMMRDNLFEIVTTSRTFYVQADSPEE
MHSWIKAVSGAIVAQRGPGRSASSEHPPGPSESKHAFRPTNAATATSHSTASRSNSLV
STFTMEKRGFYESLAKVKPGNFKVQTVSPREPASKVTEQALLRPQSKNGPQEKDCDLV
DLDDASLPVSDV"
BASE COUNT 931 a 591 c 626 g 1086 t
ORIGIN
1 attttacatt gagtcagtga tccatttgag ttagtttttt tcctcataga cagtcgatta
61 ttccagtctt gtttgttgaa aagactgtcc tttctctaca aaattgcctt ggcaccttgg
121 ttgaaaatta actgttctct cttcctgttt actagaagaa tttttaaaag accagtgtta
181 tttttttcct taagggattg gtagaattca catatgaact atttctaggc tttgactttt
241 ctttttgggg ttttagtagt gaattcattt gctttagtag aaataggtac ttcagatttt
301 ctttttgtct tgtgtcagtt ttttcaaagt tgtgtttttt caaagaattt gtttacttct
361 aaattgtcaa atttgtttgc atgaattctt attacccact taatgtctat agggtgtgta
421 gtgtgtactt cctaatattg gtgatttgct ttctctcttt cacttggttc acatagctat
481 agatttatca atttgatctt ttcaagaaac agcttttggt tttaatttgt attgtttgtt
541 ttcaatttta ttagtttctt ttctgttatt tattattccc tttctatttt gggtttactt
601 tacctttttc tagcttttta gggtggagtt tatgccattc atattagacc ttttctaata
661 aaaatatctt aagactataa attttctttc aaaatcacct ttagctgcat actacaaatt
721 ttgactttta aaatttttca tttagttaag aatgttttct gatttccctt ttgatttctt
781 cttttaccca tattttattt aaaagtgtat tttaattttc aaatagctat tcaggtgata
841 atttcatcta tagcactaaa aaccaatgaa aattctgaca tatatttgtt tataaaattc
901 cttgaatgct ctgtatattg tatttatatg gtatatacct gagggctttt ctgtagcata
961 aaagaacagt tcattatttt tcactgttct ctgggttgaa ggagctcatt tgggcagctc
1021 catcttgggg gtctctctct tgtagttgca gtcagatggc agctggaatg agagtcatct
1081 gaaggcttga ctgggctgga tggtcaagat agcctcttca ctcactctgc tagaatgact
1141 gggacagctg ggtgtgggct ggtcacctct ctccgcacag cttcttcatg ggactagttg
1201 gctttcacac aacggggcag tctgaaggca gtcagatttc ctacatgaca gctgacttct
1261 agagtgagca ttctaagaca ttgagttttt tcaagtagat aatttatttg ctctactctt
1321 tcaaactaag aagtaagata aatgtatggg gccagtcatt gtagaaactg cctgtctggc
1381 tcttgctgat tgaattcctt tggtgcagtt tagcatgttc ctctgtgttc tgcatctcct
1441 gtagtgtaat gttcaagctc agaaatgcct tatgtggatc gtcagaatcg catttgtggt
1501 tttctagaca ttgaagaaaa tgaaaacagt gggaaatttc ttcgaaggta cttcatactg
1561 gataccagag aagatagttt cgtgtggtac atggataatc cacagaacct accttctgga
1621 tcatcacgtg ttggagccat taagcttacc tacatttcaa aggttagcga tgctactaag
1681 ctaaggccaa aggcggagtt ctgttttgtt atgaatgcag gaatgaggaa gtacttccta
1741 caagccaatg atcagcagga cctagtggaa tgggtaaatg tgttaaacaa agctataaaa
1801 attacagtac caaagcagtc agactcacag cctaattctg ataacctaag tcgccatggt
1861 gaatgtggga aaaagcaagt gtcttacaga actgatattg ttggtggcgt acccatcatt
1921 actcccactc agaaagaaga agtaaatgaa tgtggtgaaa gtattgacag aaataatctg
1981 aaacggtcac aaagccatct tccttacttt actcctaaac cacctcaaga tagtgcggtt
2041 atcaaagctg gatattgtgt aaaacaagga gcagtgatga aaaactggaa gagaagatat
2101 tttcaattgg atgaaaacac aataggctac ttcaaatctg aactggaaaa ggaacctctt
2161 cgtgtaatac cacttaaaga ggttcataaa gtccaggaat gtaagcaaag cgacataatg
2221 atgagggaca acctctttga aattgtaaca acgtctcgaa ctttctatgt gcaggctgat
2281 agccctgaag agatgcacag ttggattaaa gcagtctctg gcgccattgt agcacagcgg
2341 ggtcccggca gatctgcgtc ttctgagcat ccccccggtc cttcagaatc caaacacgct
2401 ttccgtccta ccaacgcagc caccgccacc tcacattcca cagcctctcg cagcaactct
2461 ttggtctcaa cctttaccat ggagaagcga ggattttacg agtctcttgc caaggtcaag
2521 ccagggaact tcaaggtcca gactgtctct ccaagagaac cagcttccaa agtgactgaa
2581 caagctctgt taagacctca aagtaaaaat ggccctcagg aaaaagattg tgacctagta
2641 gacttggacg atgcgagcct tccggtcagt gacgtgtgag gcagaagcgc acggagcctg
2701 cctgcctctg ccgtcctcag tttcctttca tgaggcttct agccaaagat gataaagggg
2761 gaaatggttt ttagtgcgta tattatactg cctcttaggt gtactcttta taagctggta
2821 aaccaagaat ctagggagtg gccaaactaa atataatttc tttaaaaaag aaagaaaaag
2881 gaaaaatcca aaatatctca gtatcatctg tctgaagcat tgtgtgttct cattcgggtg
2941 gtaacaatgt atgtgtaata tttttttctt agtgattttg acagtttaaa tgtttaacaa
3001 cttaaagcat taaaaatgct tattaataac tttggtcatt taaaaaatgc tacaatgact
3061 tcctattaaa ggttcaatat ttacacattc ttattggttg atattaccac atgaaatatt
3121 gccagaccaa gatacctaaa ctcatgatgt ctgtggtgct gtaaaattta tactaaaatg
3181 tggactattt tgaaattata accatttttg atgccctgaa aaaaaaaaaa aaaa
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