LOCUS BC042452 3846 bp mRNA linear HUM 19-MAR-2009
DEFINITION Homo sapiens solute carrier organic anion transporter family,
member 1A2, mRNA (cDNA clone MGC:42358 IMAGE:4820050), complete
cds.
ACCESSION BC042452
VERSION BC042452.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3846)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3846)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-JAN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 71 Row: b Column: 10
The stop codon of the CDS annotated on this record is located > 55
bases upstream of a splice junction, and therefore the mRNA is
predicted to be subject to nonsense-mediated mRNA decay (NMD).
FEATURES Location/Qualifiers
source 1..3846
/db_xref="H-InvDB:HIT000097237"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:42358 IMAGE:4820050"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_95"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3846
/gene="SLCO1A2"
/gene_synonym="OATP"
/gene_synonym="OATP-A"
/gene_synonym="OATP1A2"
/db_xref="GeneID:6579"
/db_xref="HGNC:HGNC:10956"
/db_xref="MIM:602883"
CDS 92..1318
/gene="SLCO1A2"
/gene_synonym="OATP"
/gene_synonym="OATP-A"
/gene_synonym="OATP1A2"
/codon_start=1
/product="SLCO1A2 protein"
/protein_id="AAH42452.2"
/db_xref="GeneID:6579"
/db_xref="HGNC:HGNC:10956"
/db_xref="MIM:602883"
/translation="MFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGS
FEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVS
GNLSSNSFLCMENGTQILRPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGI
SYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTD
TRWVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNADIIKNENEDKQKEEVKK
EKYGITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDA
IFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCEN
SSVVGINTSYEGYVVF"
BASE COUNT 1166 a 654 c 670 g 1356 t
ORIGIN
1 aataattatt tattctttgg agcaattggg tgaagtatgt ttttatgagc aaatttacct
61 ttctctccaa gttctcccaa atttggaaac catgtttctg ttggcaataa catgtgcatt
121 tgtatccaaa acactgtctg gatcttatat gaattccatg ctcacacaaa tagagagaca
181 attcaacatc ccaacatctc tagttggatt cattaatgga agctttgaga ttggaaatct
241 tttgttgatt atatttgtga gttattttgg aaccaaactg catagaccta taatgattgg
301 cattggatgt gtggttatgg gcttaggctg tttcttaaaa tcactacctc atttcctcat
361 gaaccaatat gaatatgaat ctacagtttc agtttcaggc aacttgtcct caaacagttt
421 cttgtgtatg gaaaatggaa cccagatttt aagaccaacg caggatccat cagagtgtac
481 aaaggaagtt aaatcattaa tgtgggtgta cgtcctagta ggcaatattg tacgtggaat
541 gggtgaaact cccatcctgc ctttgggtat ttcctatata gaagattttg ccaaatttga
601 aaattctcct ttatatattg ggcttgtaga aacaggagct attattggtc ctttgattgg
661 acttttgttg gcatcattct gtgcaaatgt ttatgttgac actggatttg tgaacacaga
721 tgatctgatc ataactccca ctgacactcg ttgggtcggt gcatggtggt ttggctttct
781 gatttgtgca ggagttaacg tgctcactgc cattcctttt ttctttttgc ccaacacact
841 tccaaaggaa ggactagaga ctaatgctga catcattaaa aatgaaaatg aagacaaaca
901 aaaagaagag gtcaagaagg aaaaatatgg aatcactaaa gattttctac ctttcatgaa
961 aagtctttcc tgcaatccaa tttatatgct tttcatactt gtaagtgtga tacagttcaa
1021 tgcattcgtt aacatgatct ccttcatgcc taaataccta gaacagcaat atggaatatc
1081 atcttcagat gcaatctttc taatgggtat ttataactta cctccaatat gtattggata
1141 tataattggt ggtttaatta tgaagaagtt caagattact gtcaaacaag ctgcccacat
1201 aggatgttgg ttatccttac ttgagtatct tctctatttt ttatcttttc tcatgacttg
1261 tgaaaattct tcagttgttg gaataaatac ctcttatgaa gggtatgttg ttttctaatg
1321 aatgtgagaa tctttcaaca aatggttaat atgatatttt ttacaatggc aatgcacgat
1381 cagatcattt tcttattgga gttaatgata gtaatccatg cttttcctgt atctttcctc
1441 catctgtcaa tcaagccaat ctatccaagc tctaggctta ttaatgaggt tgggaacata
1501 tcacagggtg agtgaattta tgattgtatg tgcatgtggg tgtgtgtgca tgattgtgat
1561 atccgagtag acattatcct atgaaagaaa ctacctacag tttcaggttg tattaaaata
1621 tgttatccat atatcttata ctcccataac tgagtaaaac taagagttga ttatacagtc
1681 aaaatggcct ttatatgttt ccccaatggg cttaagtttg gcataactaa atcataatac
1741 atgataaatt aattaataca taattcatat atttcattta tattgctatg tctaaaatat
1801 tgaatcattt catattttgt attttaaagg ttatctgggt tttactgaaa tgttttccat
1861 agtgatgtac attaaaagag ttcacctgta gggcgtattt tgacaatcaa gctatcagtt
1921 aaaatgaaat aaagaacatc ctaaaatgtt ttttcaaaat tatcaaggtt tattagattg
1981 aaataatttc aaatgtaaaa tagtaatata attttacata tgctatttga tttgagactc
2041 atgagcttca tctaagataa gcattattat ctccacttta cagattaaat tgagattcag
2101 agaaatttaa tgataaaagc agttcatttc aaatctcttc aactacatca atatagaaat
2161 ggattttaaa attggaataa attttaaaga ttgcctccat ctccaatgat gctgattccc
2221 agacagaatg tgtagaaagt cgcactgtga tctagtctga atgcagtctc taaactgcta
2281 tgcaagtgct ctttcaatca tattacaagc actggtcact ttttatatta gtagaatgca
2341 cttctttaat tcaaatacct atgtttctgg agctaaatgt attatctata ttacaaatgg
2401 aactttcaga tttttatctt catgctagtc ctgtcttgct atttgctacc taatggatga
2461 atcacagaga ttagttcatc ttcatctttc gagatctaat agtatgtgaa aacatgactc
2521 cacatggtag gtgctcaatt aatgcttgtt tattgcctat atattcttct gagataaatc
2581 attgaaggag tggctatgtg gtcatcaaag caggtctctt ttataccaaa gctatagtaa
2641 acaggtcaca cattgatgac tggaaaattt ctctttctat tcatgggagg agaggaaatc
2701 taactgggga ttgagatgaa aagaagaaaa aaaggattga atcctctttt aatatctatg
2761 gcattatttt aaatcacttc agaattccac aagatttata tgtggaaaat gacatctttg
2821 ctgattgcaa tgtggattgc aactgtccat ctaaaatatg ggatcctgtg tgtggaaaca
2881 atggcttgtc atatctgtca gcttgtcttg ctggttgtga gacatccatt ggaacgggaa
2941 taaacatggt gttccaaaat tgcagctgta ttcaaacatc aggaaattca tctgcagttc
3001 ttgggctgtg cgacaaagga cctgactgtt ccttgatgct ccagtacttc ctaatcttgt
3061 cagcgatgag cagtttcatt tattctttgg ctgccatacc tggatatatg gttctcttga
3121 ggtgtatgaa atctgaagag aagtcccttg gtgtgggatt acatacattt tgcacaagag
3181 tatttgctgg cattcctgca cctatatatt ttggcgcttt aatggattcc acatgtttac
3241 actggggaac tttgaaatgt ggtgagtcag gggcatgcag gatatatgat tccaccacct
3301 tcaggtaaag ataataattt gtttaaaatt gttttataag catagactgt gcataacgca
3361 gcaccattca cacgtaactt tttctttgtc aagtgaaaag aatacttttg tggttatttc
3421 cagcagagat actgatgtta tatctccatt ccttatttgc atactagaat tgtattttcc
3481 cattatttct caagtgcttg gtaaatataa gcatacatgg cttccctaac cttggctttc
3541 aaagtgttgt tcgttaaatt cttagcagtc aacacaatat tgaaggtaat ggttgtacac
3601 tgatacctat ccaatttata ttgctctcta aaggctctca ttttatcctg catgatttcg
3661 tcatctcacg agtctgaagc ctcacttcct ctcaccacca gtctctggtc tccaaaatca
3721 tatattttct ccctctttac attttgctga aacaatcttc ttcatgtctc ctaatgcctt
3781 ctctttggta aatacaaatc taattttgaa taaaactctt tgttatttct aaaaaaaaaa
3841 aaaaaa
//