LOCUS BC042138 1251 bp mRNA linear HUM 21-OCT-2003
DEFINITION Homo sapiens pyroglutamyl-peptidase I, mRNA (cDNA clone MGC:52179
IMAGE:5935845), complete cds.
ACCESSION BC042138
VERSION BC042138.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1251)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1251)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (02-JAN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Daniel McVicar, DBS/NCI
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 44 Row: p Column: 1
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 8923197.
FEATURES Location/Qualifiers
source 1..1251
/db_xref="H-InvDB:HIT000052657"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:52179 IMAGE:5935845"
/tissue_type="Blood, natural killer cell"
/clone_lib="NIH_MGC_106"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1251
/gene="PGPEP1"
/gene_synonym="FLJ20208"
/gene_synonym="Pcp"
/gene_synonym="PGP"
/gene_synonym="PGP-I"
/gene_synonym="PGPI"
/db_xref="GeneID:54858"
CDS 424..822
/gene="PGPEP1"
/gene_synonym="FLJ20208"
/gene_synonym="Pcp"
/gene_synonym="PGP"
/gene_synonym="PGP-I"
/gene_synonym="PGPI"
/codon_start=1
/product="PGPEP1 protein"
/protein_id="AAH42138.1"
/db_xref="GeneID:54858"
/translation="MATTVTLEKCGHNKGYKGLDNCRFCPGSQCCVEDGPESIDSIID
MDAVCKRVTTLGLDVSVTISQDAGRYLCDFTYYTSLYQSHGRSAFVHVPPLGKPYNAD
QLGRALRAIIEEMLDLLEQSEGKINYCHKH"
misc_feature 430..774
/gene="PGPEP1"
/gene_synonym="FLJ20208"
/gene_synonym="Pcp"
/gene_synonym="PGP"
/gene_synonym="PGP-I"
/gene_synonym="PGPI"
/note="Region: Pyrrolidone-carboxylate peptidase
(N-terminal pyroglutamyl peptidase) [Posttranslational
modification, protein turnover, chaperones]"
/db_xref="CDD:COG2039"
BASE COUNT 293 a 338 c 356 g 264 t
ORIGIN
1 gaggctgcag cggcagcagc tgtcgcgcca gtcgcaacag aagcaggtcc gaggcacagc
61 ccgatcccgc catggagcag ccgaggaagg cggtggtagt gacgggattt ggcccttttg
121 gggaacacac cgtgaacgcc agttggattg cagttcagag atgggatctc actatattgc
181 cctggctggt cttgaacttc cgggctcaaa tgatccttcc acctcggcct cccaaagaag
241 ctgggattat aggtgtgagc caccgagccc tgccatcagg agctagaaaa gctaggcctt
301 ggcgacagcg tggacctgca tgtgtacgag attccggttg agtaccaaac agtccagaga
361 ctcatccccg ccctgtggga gaagcacagt ccacagctgg tggtgcatgt gggggtgtca
421 ggcatggcga ccacagtcac actggagaaa tgtggacaca acaagggcta caaggggctg
481 gacaactgcc gcttttgccc cggctcccag tgctgcgtgg aggacgggcc tgaaagcatt
541 gactccatca tcgacatgga tgctgtgtgc aagcgagtca ccacgttggg cctggatgtg
601 tcggtgacca tctcgcagga tgccggcaga tatctctgcg actttaccta ctacacctct
661 ttgtaccaga gtcacggtcg atcagccttc gtccacgtgc ccccactggg gaagccgtac
721 aacgcggacc agctgggcag ggcactgaga gccatcattg aggagatgtt ggacctcctg
781 gagcagtcag agggcaaaat caactattgc cacaaacact gagggacgct caggtctcct
841 aagacctcat cctgctgggg accccacgag gggacatcca ccctctgggg tgtggccagg
901 aaaagacaag ctcttcagct tggggatccg atctggaaga gagattctga tctgcccacc
961 tcctcttcct ccttctctac aaaagctccg gttgattcga gggaagtggt gaaaaatttt
1021 ttttctccca ttttcctccc tgcatctggg gacacagctg ccgtgaccag ggaggccagc
1081 ctgggaggtc cagatgccca gggagaatct tggtctggtg aatccatgag ctgcgatacc
1141 acggctgggg ccatatgttc acctgctttc ctgtccgttg gtgaaggaat ttcagaattc
1201 attttatatc caagactggc ttttaccaaa tttaaaaaaa aaaaaaaaaa a
//