LOCUS BC041878 4071 bp mRNA linear HUM 29-AUG-2005
DEFINITION Homo sapiens clock homolog (mouse), mRNA (cDNA clone MGC:43753
IMAGE:5272026), complete cds.
ACCESSION BC041878
VERSION BC041878.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4071)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4071)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (23-DEC-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 74 Row: p Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 25777594.
FEATURES Location/Qualifiers
source 1..4071
/db_xref="H-InvDB:HIT000096920"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:43753 IMAGE:5272026"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..4071
/gene="CLOCK"
/gene_synonym="KIAA0334"
/db_xref="GeneID:9575"
/db_xref="MIM:601851"
CDS 927..3467
/gene="CLOCK"
/gene_synonym="KIAA0334"
/codon_start=1
/product="CLOCK protein"
/protein_id="AAH41878.1"
/db_xref="GeneID:9575"
/db_xref="MIM:601851"
/translation="MLFTVSCSKMSSIVDRDDSSIFDGLVEEDDKDKAKRVSRNKSEK
KRRDQFNVLIKELGSMLPGNARKMDKSTVLQKSIDFLRKHKEITAQSDASEIRQDWKP
TFISNEEFTQLMLEALDGFFLAIMTDGSIIYVSESVTSLLEHLPSDLVDQSIFNFIPE
GEHSEVYKILSTHLLESDSLTPEYLKSKNQLEFCCHMLRGTIDPKEPSTYEYVKFIGN
FKSLNSVSSSAHNGFEGTIQRTHRPSYEDRVCFVATVRLATPQFIKEMCTVEEPNEEF
TSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLENLAKCHEHLMQYGKG
KSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTVVSYAEVRAERRRELGIE
ESLPETAADKSQDSGSDNRINTVSLKEALERFDHSPTPSASSRSSRKSSHTAVSDPSS
TPTKIPTDTSTPPRQHLPAHEKMVQRRSSFSSQSINSQSVGSSLTQPVMSQATNLPIP
QGMSQFQFSAQLGAMQHLKDQLEQRTRMIEANIHRQQEELRKIQEQLQMVHGQGLQMF
LQQSNPGLNFGSVQLSSGNSSNIQQLAPINMQGQVVPTNQIQSGMNTGHIGTTQHMIQ
QQTLQSTSTQSQQNVLSGHSQQTSLPSQTQSTLTAPLYNTMVISQPAAGSMVQIPSSM
PQNSTQSAAVTTFTQDRQIRFSQGQQLVTKLVTAPVACGAVMVPSTMLMGQVVTAYPT
FATQQQQSQTLSVTQQQQQQSSQEQQLTSVQQPSQAQLTQPPQQFLQTSRLLHGNPST
QLILSAAFPLQQSTFPQSHHQQHQSQQQQQLSRHRTDSLPDPSKVQPQ"
BASE COUNT 1281 a 855 c 851 g 1084 t
ORIGIN
1 gtctgactcc agcgaccgcg cgcgggttcg agggttggcg gcgaggcgct cggtttctct
61 tcttccgtcc acccgcgctt cccgttcccc gtcaccgccg ctggcgtttg tagatttctt
121 tccgccagtg aagctgggtt ttctggagtt ggctctggcg ctctggcccc tggagtgtaa
181 tttcctacac gcagcgccgc agagtttata ttctttgaaa gtgtttgtag ctttgtagag
241 gtcctcttgt tgatggtagg tgagcctaat tctgcaagat aaaagcctag tctctgacct
301 ggcagatgaa agatcaaatc agattgtggt ttcctgctat tagaatgccg tgctattaga
361 ctttaaggct ttttagcctt ctttaaaaaa taaaaaaatt tttacagtgg aagaaaagca
421 caagaagtaa acttttacag tcgttgattt gactataacg ctgatccccc caaatcaaag
481 aatttttact tgttcctgca aagctgctgg agctcagaag ctgattctat cacattgtaa
541 gatgcctttg gataattcta cagtcctctt aaatgaatct ttagaacttg gcaagtctca
601 ctagatacct tcaatcatca ttttgagctc aaagaattct gagacttatg gttggtcata
661 tagaagagta ccttgaacct atagtttcct gaagaatcag tttaaaagat ccaaggagta
721 caaaaggcag ttattggagg aattactcaa caaaaataaa gaagtaaact aaaaaagatg
781 aaggcatagg atacaagtaa cagggaatat gacctaacta gagacccagg gaatcaccag
841 gatgatgatg aataatgatc acaagaagac agcttgtcct caggagaagt acaaatgtct
901 actacaagac gaaaacgtag tatgttatgt tgtttaccgt aagctgtagt aaaatgagct
961 cgattgttga cagagatgac agtagtattt ttgatgggtt ggtggaagaa gatgacaagg
1021 acaaagcgaa aagagtatct agaaacaaat ctgaaaagaa acgtagagat caatttaatg
1081 ttctcattaa agaactggga tccatgcttc ctggtaatgc tagaaagatg gacaaatcta
1141 ctgttctgca gaaaagcatt gattttttac gaaaacataa agaaatcact gcacagtcag
1201 atgctagtga aattcgacag gactggaaac ctacattcat tagtaatgaa gagtttacac
1261 aattaatgtt agaggctctt gatggttttt ttttagcaat catgacagat ggaagcataa
1321 tatatgtgtc tgagagtgta acttcattac ttgaacattt accatctgat cttgtggatc
1381 aaagtatatt taattttatc ccagaagggg aacattcaga ggtttataaa atactctcta
1441 ctcatctgct ggaaagtgat tcattaaccc cagaatattt aaaatcaaaa aatcagttag
1501 aattctgttg tcacatgctg cgaggaacaa tagacccaaa ggagccatct acctatgaat
1561 atgtaaaatt tataggaaat ttcaaatctt taaacagtgt atcctcttca gcacacaatg
1621 gttttgaagg aactatacaa cgcacacata ggccatctta tgaagataga gtttgttttg
1681 tagctactgt caggttagct acacctcagt tcatcaagga aatgtgcact gttgaagaac
1741 ccaatgaaga gtttacatct agacatagtt tagaatggaa gtttctgttt ctagatcaca
1801 gggcaccacc cataataggg tatttgccat ttgaagttct gggaacatca ggctatgatt
1861 actatcatgt ggatgaccta gaaaatttgg caaaatgtca tgagcactta atgcaatatg
1921 ggaaaggcaa atcatgttat tataggttcc tgactaaggg gcaacagtgg atttggcttc
1981 agactcatta ttatatcact taccatcagt ggaattcaag gccagagttt attgtttgta
2041 ctcacactgt agtaagttat gcagaagtta gggctgaaag acgacgagaa cttggcattg
2101 aagagtctct tcctgagaca gctgctgaca aaagccaaga ttctgggtca gataatcgta
2161 taaacacagt cagtctcaag gaagcattgg aaaggtttga tcacagccca accccttctg
2221 cctcttctcg gagttcaaga aaatcatctc acacggccgt ctcagaccct tcctcaacac
2281 caaccaagat cccgacggat acgagcactc cacccaggca gcatttacca gctcatgaga
2341 agatggtgca aagaaggtca tcatttagta gtcagtccat aaattcccag tctgttggtt
2401 catcattaac acagccagtg atgtctcaag ctacaaattt accaattcca caaggcatgt
2461 cccagtttca gttttcagct caattaggag ccatgcaaca tctgaaagac caattggaac
2521 aacggacacg catgatagaa gcaaatattc atcggcaaca agaagaacta agaaaaattc
2581 aagaacaact tcagatggtc catggtcagg ggctgcagat gtttttgcaa caatcaaatc
2641 ctgggttgaa ttttggttcc gttcaacttt cttctggaaa ttcatctaat atccagcaac
2701 ttgcacctat aaatatgcaa ggccaagttg ttcctactaa ccagattcaa agtggaatga
2761 atactggaca cattggcaca actcagcaca tgatacaaca acagacttta cagagtacat
2821 caactcagag tcaacaaaat gtactgagtg ggcacagtca gcaaacatct ctacccagtc
2881 agacacagag cactcttaca gccccactgt ataacactat ggtgatttct cagcctgcag
2941 ccggaagcat ggtccagatt ccatctagta tgccacaaaa cagcacccag agtgctgcag
3001 taactacatt cactcaggac aggcagataa gattttctca aggtcaacaa cttgtgacca
3061 aattagtgac tgctcctgta gcttgtgggg cagtcatggt acctagtact atgcttatgg
3121 gccaggtggt gactgcatat cctacttttg ctacacaaca gcaacagtca cagacattgt
3181 cagtaacgca gcagcagcag cagcagagct cccaggagca gcagctcact tcagttcagc
3241 aaccatctca ggctcagctg acccagccac cgcaacaatt tttacagact tctaggttgc
3301 tccatgggaa tccctcaact caactcattc tctctgctgc atttcctcta caacagagca
3361 ccttccctca gtcacatcac cagcaacatc agtctcagca acagcagcaa ctcagccggc
3421 acaggactga cagcttgccc gacccttcca aggttcaacc acagtagcac acgtgcttcc
3481 tctcttgaca tcaagggagg aaggggatgg cccattaaga gttactcaga tgacctgagg
3541 aaaggaggga aagttccagc agtttcatga gatgcagtat tgagtgttct agttcctgga
3601 attagttggc agagaaaatg ctgcctagtg ctacagatgt acattaaata ccagccagca
3661 ggaggtgatc ataggggcat agccagttct gacagtgttt taggtgcctg gatatttttt
3721 gatggaaaaa gaatatattg ccaaatatta agaagctcag ctatgaaatg acctccaggg
3781 aatcagaaag gcactaatga tgttagtaac ttttagtggt tctgtgcctc ttatcaagtg
3841 ttacagagga cataccactg ccatgtcagg ggtttgctta cagtgatgcc atgaagacag
3901 tccagtagac ttggtagcga ccccctcccc caacccctct cccttttcag ataatgatgg
3961 aacagtaatt actttcagaa tgttgtgtgg gttcaaattc tctatgtaca gatgatgtaa
4021 aaatatgtat atgtctagat aaaaggagag aaagcaaaaa aaaaaaaaaa a
//