LOCUS BC041407 4282 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens glutamate receptor, metabotropic 3, mRNA (cDNA clone
MGC:44041 IMAGE:5284378), complete cds.
ACCESSION BC041407
VERSION BC041407.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4282)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4282)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (16-DEC-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 75 Row: m Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 46358416.
FEATURES Location/Qualifiers
source 1..4282
/db_xref="H-InvDB:HIT000052554"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:44041 IMAGE:5284378"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_95"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..4282
/gene="GRM3"
/gene_synonym="GLUR3"
/gene_synonym="GPRC1C"
/gene_synonym="mGlu3"
/gene_synonym="MGLUR3"
/db_xref="GeneID:2913"
/db_xref="HGNC:HGNC:4595"
/db_xref="MIM:601115"
CDS 1107..3746
/gene="GRM3"
/gene_synonym="GLUR3"
/gene_synonym="GPRC1C"
/gene_synonym="mGlu3"
/gene_synonym="MGLUR3"
/codon_start=1
/product="glutamate receptor, metabotropic 3"
/protein_id="AAH41407.1"
/db_xref="GeneID:2913"
/db_xref="HGNC:HGNC:4595"
/db_xref="MIM:601115"
/translation="MKMLTRLQVLTLALFSKGFLLSLGDHNFLRREIKIEGDLVLGGL
FPINEKGTGTEECGRINEDRGIQRLEAMLFAIDEINKDDYLLPGVKLGVHIFDTCSRD
TYALEQSLEFVRASLTKVDEAEYMCPDGSYAIQENIPLLIAGVIGGSYSSVSIQVANL
LRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRFFNWTYVSTVAS
EGDYGETGIEAFEQEARLRNICIATAEKVGRSNIRKSYDSVIRELLQKPNARVVVLFM
RSDDSRELIAAASRANASFTWVASDGWGAQESIIKGSEHVAYGAITLELASQPVRQFD
RYFQSLNPYNNHRNPWFRDFWEQKFQCSLQNKRNHRRVCDKHLAIDSSNYEQESKIMF
VVNAVYAMAHALHKMQRTLCPNTTKLCDAMKILDGKKLYKDYLLKINFTAPFNPNKDA
DSIVKFDTFGDGMGRYNVFNFQNVGGKYSYLKVGHWAETLSLDVNSIHWSRNSVPTSQ
CSDPCAPNEMKNMQPGDVCCWICIPCEPYEYLADEFTCMDCGSGQWPTADLTGCYDLP
EDYIRWEDAWAIGPVTIACLGFMCTCMVVTVFIKHNNTPLVKASGRELCYILLFGVGL
SYCMTFFFIAKPSPVICALRRLGLGSSFAICYSALLTKTNCIARIFDGVKNGAQRPKF
ISPSSQVFICLGLILVQIVMVSVWLILEAPGTRRYTLAEKRETVILKCNVKDSSMLIS
LTYDVILVILCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRV
QTTTMCISVSLSGFVVLGCLFAPKVHIILFQPQKNVVTHRLHLNRFSVSGTGTTYSQS
SASTYVPTVCNGREVLDSTTSSL"
BASE COUNT 1098 a 1094 c 1052 g 1038 t
ORIGIN
1 agcggaggtg cagttgagtc gcgagtacgg ctgagctgcg taccggcctc cctggctctc
61 acactccctc tctgctcccg ctctcctaat ctcctctggc atgcggtcag ccccctgccc
121 agggaccaca ggagagttct tgtaaggact gttagtccct gcttacctga aagccaagcg
181 ctctagcaga gctttaaagt tggagccgcc accctcccta ccgccccatg ccccttcacc
241 ccactccgaa attcaccgac ctttgcatgc actgcctaag gatttcagag tgaggcaaag
301 cagtcggcaa atctaccctg gcttttcgta taaaaatcct ctcgtctagg taccctggct
361 cactgaagac tctgcagata tacccttata agagggaggg tgggggaggg aaaagaacga
421 gagagggagg aaagaatgaa aaggagagga tgccaggagg tccgtgcttc tgccaagagt
481 cccaattaga tgcgacggct tcagcctggt caaggtgaag gaaagttgct tccgcgccta
541 ggaagtgggt ttgcctgata agagaaggag gaggggactc ggctgggaag agctcccctc
601 ccctccgcgg aagaccactg ggtcccctct ttccccaacc tcctccctct cttctactcc
661 acccctccgt tttcccactc cccactgact cggatgcctg gatgttctgc caccgggcag
721 tggtccagcg tgcagccggg agggggcagg ggcagggggc actgtgacag gaagctgcgc
781 gcacaagttg gccatttcga gggcaaaata agttctccct tggatttgga aaggacaaag
841 ccagtaagct acctcttttg tgtcggatga ggaggaccaa ccatgagcca gagcccgggt
901 gcaggctcac cgccgccgct gccaccgcgg tcagctccag ttcctgccag gagttgtcgg
961 tgcgaggaat tttgtgacag gctctgttag tctgttcctc ccttatttga aggacaggcc
1021 aaagatccag tttggaaatg agagaggact agcatgacac attggctcca ccattgatat
1081 ctcccagagg tacagaaaca ggattcatga agatgttgac aagactgcaa gttcttacct
1141 tagctttgtt ttcaaaggga tttttactct ctttagggga ccataacttt ctaaggagag
1201 agattaaaat agaaggtgac cttgttttag ggggcctgtt tcctattaac gaaaaaggca
1261 ctggaactga agaatgtggg cgaatcaatg aagaccgagg gattcaacgc ctggaagcca
1321 tgttgtttgc tattgatgaa atcaacaaag atgattactt gctaccagga gtgaagttgg
1381 gtgttcacat ttttgataca tgttcaaggg atacctatgc attggagcaa tcactggagt
1441 ttgtcagggc atctttgaca aaagtggatg aagctgagta tatgtgtcct gatggatcct
1501 atgccattca agaaaacatc ccacttctca ttgcaggggt cattggtggc tcttatagca
1561 gtgtttccat acaggtggca aacctgctgc ggctcttcca gatccctcag atcagctacg
1621 catccaccag cgccaaactc agtgataagt cgcgctatga ttactttgcc aggaccgtgc
1681 cccccgactt ctaccaggcc aaagccatgg ctgagatctt gcgcttcttc aactggacct
1741 acgtgtccac agtagcctcc gagggtgatt acggggagac agggatcgag gccttcgagc
1801 aggaagcccg cctgcgcaac atctgcatcg ctacggcgga gaaggtgggc cgctccaaca
1861 tccgcaagtc ctacgacagc gtgatccgag aactgttgca gaagcccaac gcgcgcgtcg
1921 tggtcctctt catgcgcagc gacgactcgc gggagctcat tgcagccgcc agccgcgcca
1981 atgcctcctt cacctgggtg gccagcgacg gctggggcgc gcaggagagc atcatcaagg
2041 gcagcgagca tgtggcctac ggcgccatca ccctggagct ggcctcccag cctgtccgcc
2101 agttcgaccg ctacttccag agcctcaacc cctacaacaa ccaccgcaac ccctggttcc
2161 gggacttctg ggagcaaaag tttcagtgca gcctccagaa caaacgcaac cacaggcgcg
2221 tctgcgacaa gcacctggcc atcgacagca gcaactacga gcaagagtcc aagatcatgt
2281 ttgtggtgaa cgcggtgtat gccatggccc acgctttgca caaaatgcag cgcaccctct
2341 gtcccaacac taccaagctt tgtgatgcta tgaagatcct ggatgggaag aagttgtaca
2401 aggattactt gctgaaaatc aacttcacgg ctccattcaa cccaaataaa gatgcagata
2461 gcatagtcaa gtttgacact tttggagatg gaatggggcg atacaacgtg ttcaatttcc
2521 aaaatgtagg tggaaagtat tcctacttga aagttggtca ctgggcagaa accttatcgc
2581 tagatgtcaa ctctatccac tggtcccgga actcagtccc cacttcccag tgcagcgacc
2641 cctgtgcccc caatgaaatg aagaatatgc aaccagggga tgtctgctgc tggatttgca
2701 tcccctgtga accctacgaa tacctggctg atgagtttac ctgtatggat tgtgggtctg
2761 gacagtggcc cactgcagac ctaactggat gctatgacct tcctgaggac tacatcaggt
2821 gggaagacgc ctgggccatt ggcccagtca ccattgcctg tctgggtttt atgtgtacat
2881 gcatggttgt aactgttttt atcaagcaca acaacacacc cttggtcaaa gcatcgggcc
2941 gagaactctg ctacatctta ttgtttgggg ttggcctgtc atactgcatg acattcttct
3001 tcattgccaa gccatcacca gtcatctgtg cattgcgccg actcgggctg gggagttcct
3061 tcgctatctg ttactcagcc ctgctgacca agacaaactg cattgcccgc atcttcgatg
3121 gggtcaagaa tggcgctcag aggccaaaat tcatcagccc cagttctcag gttttcatct
3181 gcctgggtct gatcctggtg caaattgtga tggtgtctgt gtggctcatc ctggaggccc
3241 caggcaccag gaggtatacc cttgcagaga agcgggaaac agtcatccta aaatgcaatg
3301 tcaaagattc cagcatgttg atctctctta cctacgatgt gatcctggtg atcttatgca
3361 ctgtgtacgc cttcaaaacg cggaagtgcc cagaaaattt caacgaagct aagttcatag
3421 gttttaccat gtacaccacg tgcatcatct ggttggcctt cctccctata ttttatgtga
3481 catcaagtga ctacagagtg cagacgacaa ccatgtgcat ctctgtcagc ctgagtggct
3541 ttgtggtctt gggctgtttg tttgcaccca aggttcacat catcctgttt caaccccaga
3601 agaatgttgt cacacacaga ctgcacctca acaggttcag tgtcagtgga actgggacca
3661 catactctca gtcctctgca agcacgtatg tgccaacggt gtgcaatggg cgggaagtcc
3721 tcgactccac cacctcatct ctgtgattgt gaattgcagt tcagttcttg tgtttttaga
3781 ctgttagaca aaagtgctca cgtgcagctc cagaatatgg aaacagagca aaagaacaac
3841 cctagtacct ttttttagaa acagtacgat aaattatttt tgaggactgt atatagtgat
3901 gtgctagaac tttctaggct gagtctagtg cccctattat taacaattcc cccagaacat
3961 ggaaataacc attgtttaca gagctgagca ttggtgacag ggtctgacat ggtcagtcta
4021 ctaaaaaaca aaaaaaaaaa acaaaaaaaa aaaaacaaaa gaaaaaaata aaaatacggt
4081 ggcaatatta tgtaaccttt tttcctatga agttttttgt aggtccttgt tgtaactaat
4141 ttaggatgag tttctatgtt gtatattaaa gttacattat gtgtaacaga ttgattttct
4201 cagcacaaaa taaaaagcat ctgtattaat gtaaagatac tgagaataaa accttcaagg
4261 ttttccaaaa aaaaaaaaaa aa
//