LOCUS BC041144 3864 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens aprataxin and PNKP like factor, mRNA (cDNA clone
MGC:47799 IMAGE:6042653), complete cds.
ACCESSION BC041144
VERSION BC041144.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3864)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3864)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-DEC-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 82 Row: n Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 27734904.
FEATURES Location/Qualifiers
source 1..3864
/db_xref="H-InvDB:HIT000052523"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:47799 IMAGE:6042653"
/tissue_type="Testis, embryonal carcinoma"
/clone_lib="NIH_MGC_92"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3864
/gene="APLF"
/gene_synonym="APFL"
/gene_synonym="PALF"
/gene_synonym="Xip1"
/db_xref="GeneID:200558"
/db_xref="HGNC:HGNC:28724"
/db_xref="MIM:611035"
CDS 123..1658
/gene="APLF"
/gene_synonym="APFL"
/gene_synonym="PALF"
/gene_synonym="Xip1"
/codon_start=1
/product="aprataxin and PNKP like factor"
/protein_id="AAH41144.1"
/db_xref="GeneID:200558"
/db_xref="HGNC:HGNC:28724"
/db_xref="MIM:611035"
/translation="MSGGFELQPRDGGPRVALAPGETVIGRGPLLGITDKRVSRRHAI
LEVAGGQLRIKPIHTNPCFYQSSEKSQLLPLKPNLWCYLNPGDSFSLLVDKYIFRILS
IPSEVEMQCTLRNSQVLDEDNILNETPKSPVINLPHETTGASQLEGSTEIAKTQMTPT
NSVSFLGENRDCNKQQPILAERKRILPTWMLAEHLSDQNLSVPAISGGNVIQGSGKEE
ICKDKSQLNTTQQGRRQLISSGSSENTSAEQDTGEECKNTDQEESTISSKEMPQSFSA
ITLSNTEMNNIKTNAQRNKLPIEELGKVSKHKIATKRTPHKEDEAMSCSENCSSAQGD
SLQDESQGSHSESSSNPSNPETLHAKATDSVLQGSEGNKVKRTSCMYGANCYRKNPVH
FQHFSHPGDSDYGGVQIVGQDETDDRPECPYGPSCYRKNPQHKIEYRHNTLPVRNVLD
EDNDNVGQPNEYDLNDSFLDDEEEDYEPTDEDSDWEPGKEDEEKEDVEELLKEAKRFM
KRK"
BASE COUNT 1350 a 677 c 735 g 1102 t
ORIGIN
1 gcctttgagg ccctccctcg gtgttttttc ccagggcgtg ggcttgcccc gcgcgtgtct
61 gtggagggcg gaaacagcgg aggggccagt ctcctggcga aggggcctaa tccttgcccg
121 ccatgtccgg gggcttcgag ctgcagccgc gggacggcgg tccccgggtg gccctggcgc
181 ccggggagac ggtgatcggc cgcgggccgc tgctgggaat aacagacaag agagtatcca
241 gaagacatgc cattcttgag gtggcaggtg gtcagctgcg aatcaaaccg atacacacaa
301 atccatgttt ttaccagtct tcagagaaga gtcagctctt accattgaag ccaaatctat
361 ggtgctattt gaatcctgga gacagctttt ctttgttagt tgacaaatac attttccgca
421 ttctctctat accctctgaa gtggaaatgc aatgtacctt aagaaacagt caagtgcttg
481 atgaagataa tatattgaat gaaacaccaa aatcccccgt gattaattta cctcatgaga
541 ctactggtgc ctcacaactg gaaggaagca cagaaatagc caagacccag atgactccca
601 caaatagtgt gtctttccta ggtgaaaata gagactgcaa taagcagcag ccaatccttg
661 ccgagaggaa aagaatcctt ccaacttgga tgttagcaga acatttaagt gatcaaaacc
721 tttcagtacc agcaatcagt ggaggtaatg taatccaggg aagtggaaaa gaagaaatct
781 gcaaagataa atcccagcta aacacaaccc agcaaggaag aaggcaatta atttcatcag
841 gaagttcaga aaatacatca gcagaacaag acacaggaga agagtgcaaa aatactgatc
901 aggaagagtc taccatttca tccaaggaaa tgccacaatc attttctgca atcacattaa
961 gtaacacaga gatgaataat attaagacta atgcacagag aaacaaactt ccaatagagg
1021 aacttggtaa agtttctaaa cataaaattg ccactaaaag aacaccacat aaagaagatg
1081 aggcaatgag ctgttctgaa aattgttcga gtgcccaggg cgactcactt caggatgagt
1141 ctcaagggtc tcattctgag tccagctcta atccctccaa tcctgaaact ttgcatgcaa
1201 aggcaactga ttcagttcta caaggttctg aaggaaacaa ggtcaagagg acatcctgca
1261 tgtatggggc aaactgctat aggaagaatc ctgttcattt tcaacatttt agccatcctg
1321 gtgatagtga ttatggaggt gtacaaatcg tgggccaaga tgagactgat gaccggcctg
1381 aatgtcccta tggaccatcc tgttatagga agaatcccca gcacaagata gaatatagac
1441 ataatacgct tccagtgaga aatgttttag atgaagataa tgataatgtt gggcaaccca
1501 atgagtatga cctgaacgac agctttctag atgatgagga agaagactat gagccaacag
1561 atgaagattc tgactgggaa ccaggaaagg aagatgaaga gaaggaagat gtggaagagc
1621 ttttgaaaga agcaaaaagg tttatgaaaa gaaaatagta actaacttct gtagtcatat
1681 ctgccttaca tttacttttt ctttgtggga aaacatttat gaactaagga ggtacttaag
1741 tgacagttat tttccttctt ttgatagtta atgactttta ctactgactc tttacaaatg
1801 agacattgaa acgtcagcct tcagtataat agatggaatt ttttgttgcc ttgccttttc
1861 tttcctactt aaagcatctg gaaataggaa gacagagaag gtagagtaaa aatggatatt
1921 ttttatgtac tttgtatatt ggtaataaaa agtaaaagcc ataggttgca taaaactttg
1981 gtctttttaa atttttttcc aaagattatg gagtactctg caagtataac caggcaaagt
2041 acatgaaaac atgcctcttt tcattgttac tgaagtaatt ctgtaagcag aaccaggctt
2101 taaaaaatgc agccattaca taatggcgtt ttttttctag taccttagat gtgagctttg
2161 caatttcact tactactttt atccttcaaa acttgggaag attggttcca aatgggtact
2221 gaaaatagat tcaactaggc tgtagaagag aaatgttcac catgtaggga atgttatttt
2281 gtgttccaca tctgcaattt actgtatgtt tgaatttaaa agtaaaaaaa ctcaaaaaac
2341 ttgacctttt ttttcaaact aaagtcctag ctgattattt taactctcag tgtgctgtct
2401 ttatattaag aatagagaaa cgacataact ttctcaaatg gcattagttt tgccttagtt
2461 tttttgacct cagatgaaag tagcaagttg tttgccagtt gaaagttcaa gattctggcc
2521 tcccatatca agaagaaacc acttattctc cagttttaca aagtatcttt ctgtatttct
2581 gttctaaaac tactttaagc cctataatgc tcttcatatt acgtgacttt gaattgttaa
2641 aatgtagttt agaatcttta ataacagttg ggttgtgtac acagagcagg agatatttat
2701 tgaaatcata aatcactaag ccaaaagaat ctttgttaaa tgctattatt ttctactcta
2761 aaggaaccta aaaatttata tcttaaaaga tcaaaacata tttataataa tattttctca
2821 ttgctttaaa atatatctcc cagtaattat acaatattta atatttactt aaactggaac
2881 aagaataaga taaacatttc tctagactat aacctattat tctgattttt atctcttatt
2941 gttatttggg aactattttt ccccttataa tgtcccttta gccttggtag tataacaaat
3001 ctacgaatgt aatatttaac ttattctcat ccctgccact aacttaatcc ttgaagtgtt
3061 acataatcta ctcctaggta tatacccaga ggaattgaaa acatttccac ataaaaactg
3121 tacacaatgt caatagaagc attattctta acagccaaaa agtataaaca cccaaagtct
3181 atcaactatc aactgggtga atggataagc aaaacgtggt atatctgtgc aatggaatat
3241 tatttggtca taaaaaggaa taaagtactg atacatgcta caagatagat gaaccttgaa
3301 ggcaagtaaa agaagccaga cacaaaaggc cacatactgt atgaactcat ttatatgaaa
3361 tttccaaaac aggcaaatcc ataaagacag aaagcaaatt tgtggttgcc agggacttgg
3421 ggaggaagaa tggggagtga ctgctaatga gtataggatt tccttttgag tgataaaaat
3481 gttctaagat tagatggcag tgatggttgc acaactctgt aaatatatta caaacaatgc
3541 attgtacact ttcaaagggt agatttcatt gcacgtgaac tatatatttc aataaatctg
3601 tcacaaaaaa gtaatgcaaa gggtaatacc agtcttttag aaggaaaaaa atatttaata
3661 tcaaaggata ttcttcgtag taatgtaata gttcatggta gctgctttta acgatacagt
3721 tttaatgcaa ctttcataat catcctgaag acacttttga gtataactat tgtataaata
3781 aatgtatagc ttaattgaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3841 aaaaaaaaaa aaaaaaaaaa aaaa
//