LOCUS BC041058 2483 bp mRNA linear HUM 04-JAN-2007
DEFINITION Homo sapiens arachidonate 12-lipoxygenase, 12R type, mRNA (cDNA
clone MGC:52260 IMAGE:5441563), complete cds.
ACCESSION BC041058
VERSION BC041058.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2483)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2483)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-DEC-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 44 Row: i Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4502052.
FEATURES Location/Qualifiers
source 1..2483
/db_xref="H-InvDB:HIT000052489"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:52260 IMAGE:5441563"
/tissue_type="Brain, astrocytoma, grade IV"
/clone_lib="NIH_MGC_98"
/lab_host="DH10B"
/note="Vector: pOTB7"
gene 1..2483
/gene="ALOX12B"
/gene_synonym="12R-LOX"
/db_xref="GeneID:242"
/db_xref="HGNC:HGNC:430"
/db_xref="MIM:603741"
CDS 290..2395
/gene="ALOX12B"
/gene_synonym="12R-LOX"
/codon_start=1
/product="arachidonate 12-lipoxygenase, 12R type"
/protein_id="AAH41058.1"
/db_xref="GeneID:242"
/db_xref="HGNC:HGNC:430"
/db_xref="MIM:603741"
/translation="MATYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRD
FATGAVGQYTVQCPQDLGELIIIRLHKERYAFFPKDPWYCNYVQICAPNGRIYHFPAY
QWMDGYETLALREATGKTTADDSLPVLLEHRKEEIRAKQDFYHWRVFLPGLPSYVHIP
SYRPPVRRHRNPNRPEWNGYIPGFPILINFKATKFLNLNLRYSFLKTASFFVRLGPMA
LAFKVRGLLDCKHSWKRLKDIRKIFPGKKSVVSEYVAEHWAEDTFFGYQYLNGVNPGL
IRRCTRIPDKFPVTDDMVAPFLGEGTCLQAELEKGNIYLADYRIMEGIPTVELSGRKQ
HHCAPLCLLHFGPEGKMMPIAIQLSQTPGPDCPIFLPSDSEWDWLLAKTWVRYAEFYS
HEAIAHLLETHLIAEAFCLALLRNLPMCHPLYKLLIPHTRYTVQINSIGRAVLLNEGG
LSAKGMSLGVEGFAGVMVRALSELTYDSLYLPNDFVERGVQDLPGYYYRDDSLAVWNA
LEKYVTEIITYYYPSDAAVEGDPELQSWVQEIFKECLLGRESSGFPRCLRTVPELIRY
VTIVIYTCSAKHAAVNTGQMEFTAWMPNFPASMRNPPIQTKGLTTLETFMDTLPDVKT
TCITLLVLWTLSREPDDRRPLGHFPDIHFVEEAPRRSIEAFRQRLNQISHDIRQRNKC
LPIPYYYLDPVLIENSISI"
BASE COUNT 523 a 807 c 660 g 493 t
ORIGIN
1 ggcctgggtg gcgaattcgg cacgagggcc cagacacctg ctcactcacc accagctggg
61 ctccgcctgg gcctgcccgg cacccacccc ggccaccaag ggcagcagct tttccagaat
121 ttggctggca ggcccagtca ccccacctcg ccacctcacc actgcacctc ggaggccagc
181 cctgtccact ccactctgtg cctggcttct cttgcctgcc ttgggccttc gtgtggcccc
241 tccacggtgt ctgggactga gtgcccctct tgcctcctga agagcagcca tggccaccta
301 caaagtcagg gtggccacag gcaccgacct cttgtcggga acacgggact ccatctcact
361 gaccattgtg gggacacaag gagagagcca taagcagctg ctgaaccact ttgggagaga
421 ctttgcaact ggggcggtgg gccagtacac cgtgcagtgc cctcaggacc tgggtgagct
481 catcatcatc cgcctgcaca aagagcggta cgccttcttc cccaaggacc cttggtactg
541 caactatgtg cagatctgtg cccccaacgg ccgtatctac cacttccccg cctaccagtg
601 gatggatggc tacgagaccc tggcactccg ggaggccaca ggaaagacaa cagcagatga
661 ctcgctcccc gtcctcctgg agcacagaaa agaggagatc agagccaagc aggacttcta
721 ccactggcga gtctttcttc ctggcctgcc cagctatgtg cacattccca gttaccgccc
781 tccggtgcgg aggcatcgca accccaaccg gcctgagtgg aatggctata ttccgggatt
841 cccaattctc atcaacttta aggccaccaa gttcctgaac ttaaatctcc gctactcctt
901 cctcaagacg gcctccttct tcgtccgcct ggggcccatg gcactggctt tcaaagtccg
961 cggcctgttg gactgcaaac attcgtggaa gaggctgaag gacattagga aaattttccc
1021 tggcaagaaa tctgtcgtct ccgagtacgt ggccgagcac tgggcagagg acaccttctt
1081 tgggtaccag tacctcaacg gcgtcaaccc cggcctgatc cgccgctgca cgcggatccc
1141 agacaagttc cccgtcacag acgacatggt ggctccgttc ctgggcgagg gaacgtgctt
1201 gcaagcggag ctggagaagg ggaacattta cctggccgac taccgcatca tggagggcat
1261 ccccaccgtg gagctcagcg gccggaagca gcaccactgc gcccccctct gcctgctgca
1321 ctttggaccc gagggcaaga tgatgcccat cgccatccag ctcagccaga cccctgggcc
1381 agattgcccc atcttcctgc ccagtgattc tgagtgggac tggctgctag ccaagacgtg
1441 ggtacgctat gcggagttct acagccacga ggccatcgcc cacctgctgg agacacacct
1501 cattgctgag gccttctgcc tggccttgct gaggaacctg cccatgtgcc accccctcta
1561 caagctcctc atcccccata cccgatacac cgtccagatc aacagcattg gccgggccgt
1621 tctcctcaat gagggggggc tctctgccaa gggcatgtcc ctgggcgtgg aaggctttgc
1681 tggggtgatg gtacgggctc tgtcggagct cacctatgac agcctctacc tccccaatga
1741 ctttgtggag cgtggggtcc aggacctgcc tggatattac taccgcgatg acagcttggc
1801 ggtgtggaat gcactggaga agtatgtgac ggagatcatc acctattatt acccgagtga
1861 cgcagccgtg gagggtgatc cggaattgca gtcttgggtg caggaaatat ttaaagagtg
1921 cctcctgggg cgggagagct caggcttccc taggtgcttg cgaaccgtgc ctgagctgat
1981 ccgatatgtc actatagtca tctacacctg ctctgccaag cacgctgctg tcaacacagg
2041 ccagatggag ttcaccgcct ggatgcccaa cttcccagcg tccatgcgga atccaccgat
2101 tcagactaag gggctgacca ctctggagac cttcatggac acgttgccgg atgtgaagac
2161 cacgtgcatc acgctgctgg tgctctggac cctcagccga gagcctgacg acaggcggcc
2221 cctgggacac ttcccggaca ttcacttcgt ggaggaggcc ccgcggagga gcatagaggc
2281 gttccgccag cgcctgaacc agatctcaca cgacatccgc cagcgcaaca agtgccttcc
2341 catcccctac tactacctgg acccggtgct gattgagaac agcatttcta tttaggagcg
2401 cgcttcccgt ctctcctctc cccattctgt gccctactat tttcaacaaa acaaaacaaa
2461 caagcaaaaa aaaaaaaaaa aaa
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