LOCUS BC041016 1912 bp mRNA linear HUM 07-OCT-2003
DEFINITION Homo sapiens succinate dehydrogenase complex, subunit A,
flavoprotein (Fp), mRNA (cDNA clone MGC:52232 IMAGE:3138724),
complete cds.
ACCESSION BC041016
VERSION BC041016.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1912)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1912)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (13-DEC-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 44 Row: a Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4759079.
FEATURES Location/Qualifiers
source 1..1912
/db_xref="H-InvDB:HIT000052480"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:52232 IMAGE:3138724"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1912
/gene="SDHA"
/gene_synonym="FP"
/gene_synonym="SDH2"
/gene_synonym="SDHF"
/db_xref="GeneID:6389"
/db_xref="MIM:600857"
CDS 73..1632
/gene="SDHA"
/gene_synonym="FP"
/gene_synonym="SDH2"
/gene_synonym="SDHF"
/codon_start=1
/product="SDHA protein"
/protein_id="AAH41016.1"
/db_xref="GeneID:6389"
/db_xref="MIM:600857"
/translation="MSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRAS
AKVSDSISAQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVA
AQGGINAALGNMEEDNWRWHFYDTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGC
LITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDH
VYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQV
LRHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIEESCRPGD
KVPPIKPNAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQNHAAVFRVGSVLQEGCG
KISKLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHARE
DYKVRIDEYDYSKPIQGQQKKPFEEHWRKHTLSFVDVGTGKVTLEYRPVIDKTLNEAD
CATVPPAIRSY"
misc_feature 448..1572
/gene="SDHA"
/gene_synonym="FP"
/gene_synonym="SDH2"
/gene_synonym="SDHF"
/note="SdhA; Region: Succinate dehydrogenase/fumarate
reductase, flavoprotein subunit [Energy production and
conversion]"
/db_xref="CDD:COG1053"
BASE COUNT 467 a 465 c 574 g 406 t
ORIGIN
1 gccgaccccg gtgtggtgcg caggcgcagt ctgcgcaggg actggcggga ctgcgcggcg
61 gcaacagcag acatgtcggg ggtccggggc ctgtcgcggc tgctgagcgc tcggcgcctg
121 gcgctggcca aggcgtggcc aacagtgttg caaacaggaa cccgaggttt tcacttcact
181 gttgatggga acaagagggc atctgctaaa gtttcagatt ccatttctgc tcagtatcca
241 gtagtggatc atgaatttga tgcagtggtg gtaggcgctg gaggggcagg cttgcgagct
301 gcatttggcc tttctgaggc agggtttaat acagcatgtg ttaccaagct gtttcctacc
361 aggtcacaca ctgttgcagc gcagggagga atcaatgctg ctctggggaa catggaggag
421 gacaactgga ggtggcattt ctacgacacc agcactggcg acggcacggc catgatcacc
481 agggcaggcc ttccttgcca ggacctagag tttgttcagt tccaccccac aggcatatat
541 ggtgctggtt gtctcattac ggaaggatgt cgtggagagg gaggcattct cattaacagt
601 caaggcgaaa ggtttatgga gcgatacgcc cctgtcgcga aggacctggc gtctagagat
661 gtggtgtctc ggtcgatgac tctggagatc cgagaaggaa gaggctgtgg ccctgagaaa
721 gatcacgtct acctgcagct gcaccaccta cctccagagc agctggccac gcgcctgcct
781 ggcatttcag agacagccat gatctttgct ggcgtggacg tcacgaagga gccgatccct
841 gtcctcccca ccgtgcatta taacatgggc ggcattccca ccaactacaa ggggcaggtc
901 ctgaggcacg tgaatggcca ggatcagatt gtgcccggcc tgtacgcctg tggggaggcc
961 gcctgtgcct cggtacatgg tgccaaccgc ctcggggcaa actcgctctt ggacctggtt
1021 gtctttggtc gggcatgtgc cctgagcatc gaagagtcat gcaggcctgg agataaagtc
1081 cctccaatta aaccaaacgc tggggaagaa tctgtcatga atcttgacaa attgagattt
1141 gctgatggaa gcataagaac atcggaactg cgactcagca tgcagaagtc aatgcaaaat
1201 catgctgccg tgttccgtgt gggaagcgtg ttgcaagaag gttgtgggaa aatcagcaag
1261 ctctatggag acctaaagca cctgaagacg ttcgaccggg gaatggtctg gaacacagac
1321 ctggtggaga ccctggagct gcagaacctg atgctgtgtg cgctgcagac catctacgga
1381 gcagaggcgc ggaaggagtc acggggcgcg catgccaggg aagactacaa ggtgcggatt
1441 gatgagtacg attactccaa gcccatccag gggcaacaga agaagccctt tgaggagcac
1501 tggaggaagc acaccctgtc ctttgtggac gttggcactg ggaaggtcac tctggaatat
1561 agacccgtaa tcgacaaaac tttgaacgag gctgactgtg ccaccgtccc gccagccatt
1621 cgctcctact gatgagacaa gatgtggtga tgacagaatc agcttttgta attatgtata
1681 atagctcatg catgtgtcca tgtcataact gtcttcatac gcttctgcac tctggggaag
1741 aaggagtaca ttgaagggag attggcacct agtggctggg agcttgccag gaacccagtg
1801 gccagggagc gtggcactta cctttgtccc ttgcttcatt cttgtgagat gataaaactg
1861 ggcacagctc ttaaataaaa tataaatgaa caaaaaaaaa aaaaaaaaaa aa
//