LOCUS BC040955 1858 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens bactericidal/permeability-increasing protein, mRNA
(cDNA clone MGC:48884 IMAGE:5218655), complete cds.
ACCESSION BC040955
VERSION BC040955.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1858)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1858)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-DEC-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 84 Row: e Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4502446.
FEATURES Location/Qualifiers
source 1..1858
/db_xref="H-InvDB:HIT000052469"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:48884 IMAGE:5218655"
/tissue_type="Blood, adult leukocytes"
/clone_lib="NIH_MGC_118"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1858
/gene="BPI"
/db_xref="GeneID:671"
/db_xref="HGNC:HGNC:1095"
/db_xref="MIM:109195"
CDS 38..1501
/gene="BPI"
/codon_start=1
/product="bactericidal/permeability-increasing protein"
/protein_id="AAH40955.1"
/db_xref="GeneID:671"
/db_xref="HGNC:HGNC:1095"
/db_xref="MIM:109195"
/translation="MRENLARGPCNAPRWASLMVLVAIGTAVTAAVNPGVVVRISQKG
LDYASQQGTAALQKELKRIKIPDYSDSFKIKHLGKGHYSFYSMDIREFQLPSSQISMV
PNVGLKFSISNANIKISGKWKAQKRFLKMSGNFDLSIEGMSISADLKLGSNPTSGKPT
ITCSSCSSHINSVHVHISKSKVGWLIQLFHKKIESALRNKMNSQVCEKVTNSVSSKLQ
PYFQTLPVMTKIDSVAGINYGLVAPPATTAETLDVQMKGEFYSENHHNPPPFAPPVME
FPAAHDRMVYLGLSDYFFNTAGLVYQEAGVLKMTLRDDMIPKESKFRLTTKFFGTFLP
EVAKKFPNMKIQIHVSASTPPHLSVQPTGLTFYPAVDVQAFAVLPNSSLASLFLIGMH
TTGSMEVSAESNRLVGELKLDRLLLELKHSNIGPFPVELLQDIMNYIVPILVLPRVNE
KLQKGFPLPTPARVQLYNVVLQPHQNFLLFGADVVYK"
BASE COUNT 492 a 502 c 443 g 421 t
ORIGIN
1 caacctcaag gccttgaggt tttggcagct ctggaggatg agagagaact tggccagggg
61 cccttgcaac gcgccgagat gggcgtccct gatggtgctg gtcgccatag gcaccgccgt
121 gacagcggcc gtcaaccctg gcgtcgtggt caggatctcc cagaagggcc tggactacgc
181 cagccagcag gggacggccg ctctgcagaa ggagctgaag aggatcaaga ttcctgacta
241 ctcagacagc tttaagatca agcatcttgg gaaggggcat tatagcttct acagcatgga
301 catccgtgaa ttccagcttc ccagttccca gataagcatg gtgcccaatg tgggccttaa
361 gttctccatc agcaacgcca atatcaagat cagcgggaaa tggaaggcac aaaagagatt
421 cttaaaaatg agcggcaatt ttgacctgag catagaaggc atgtccattt cggctgatct
481 gaagctgggc agtaacccca cgtcaggcaa gcccaccatc acctgctcca gctgcagcag
541 ccacatcaac agtgtccacg tgcacatctc aaagagcaaa gtggggtggc tgatccaact
601 cttccacaaa aaaattgagt ctgcgcttcg aaacaagatg aacagccagg tctgcgagaa
661 agtgaccaat tctgtatcct ccaagctgca accttatttc cagactctgc cagtaatgac
721 caaaatagat tctgtggctg gaatcaacta tggtctggtg gcacctccag caaccacggc
781 tgagaccctg gatgtacaga tgaaggggga gttttacagt gagaaccacc acaatccacc
841 tccctttgct ccaccagtga tggagtttcc cgctgcccat gaccgcatgg tatacctggg
901 cctctcagac tacttcttca acacagccgg gcttgtatac caagaggctg gggtcttgaa
961 gatgaccctt agagatgaca tgattccaaa ggagtccaaa tttcgactga caaccaagtt
1021 ctttggaacc ttcctacctg aggtggccaa gaagtttccc aacatgaaga tacagatcca
1081 tgtctcagcc tccaccccgc cacacctgtc tgtgcagccc accggcctta ccttctaccc
1141 tgccgtggat gtccaggcct ttgccgtcct ccccaactcc tccctggctt ccctcttcct
1201 gattggcatg cacacaactg gttccatgga ggtcagcgcc gagtccaaca ggcttgttgg
1261 agagctcaag ctggataggc tgctcctgga actgaagcac tcaaatattg gccccttccc
1321 ggttgaattg ctgcaggata tcatgaacta cattgtaccc attcttgtgc tgcccagggt
1381 taacgagaaa ctacagaaag gcttccctct cccgacgccg gccagagtcc agctctacaa
1441 cgtagtgctt cagcctcacc agaacttcct gctgttcggt gcagacgttg tctataaatg
1501 aaggcaccag gggtgccggg ggctgtcagc cgcacctgtt cctgatgggc tgtggggcac
1561 cggctgcctt tccccaggga atcctctcca gatcttaacc aagagcccct tgcaaacttc
1621 ttcgactcag attcagaaat gatctaaaca cgaggaaaca ttattcattg gaaaagtgca
1681 tggtgtgtat tttagggatt atgagcttct ttcaagggct aaggctgcag agatatttcc
1741 tccaggaatc gtgtttcaat tgtaaccaag aaatttccat ttgtgcttca tgaaaaaaaa
1801 cttctggttt ttttcatgtg aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
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