LOCUS BC040525 4725 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens WD repeat and FYVE domain containing 1, mRNA (cDNA
clone MGC:39547 IMAGE:5285567), complete cds.
ACCESSION BC040525
VERSION BC040525.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4725)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4725)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-NOV-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 63 Row: k Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: GenomeScan gene
prediction.
FEATURES Location/Qualifiers
source 1..4725
/db_xref="H-InvDB:HIT000052415"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:39547 IMAGE:5285567"
/tissue_type="Brain, hypothalamus"
/clone_lib="NIH_MGC_96"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..4725
/gene="WDFY1"
/gene_synonym="FENS-1"
/gene_synonym="WDF1"
/gene_synonym="ZFYVE17"
/db_xref="GeneID:57590"
/db_xref="HGNC:HGNC:20451"
CDS 16..1248
/gene="WDFY1"
/gene_synonym="FENS-1"
/gene_synonym="WDF1"
/gene_synonym="ZFYVE17"
/codon_start=1
/product="WD repeat and FYVE domain containing 1"
/protein_id="AAH40525.1"
/db_xref="GeneID:57590"
/db_xref="HGNC:HGNC:20451"
/translation="MAAEIHSRPQSSRPVLLSKIEGHQDAVTAALLIPKEDGVITASE
DRTIRVWLKRDSGQYWPSIYHTMASPCSAMAYHHDSRRIFVGQDNGAVMEFHVSEDFN
KMNFIKTYPAHQNRVSAIIFSLATEWVISTGHDKCVSWMCTRSGNMLGRHFFTSWASC
LQYDFDTQYAFVGDYSGQITLLKLEQNTCSVITTLKGHEGSVACLWWDPIQRLLFSGA
SDNSIIMWDIGGRKGRTLLLQGHHDKVQSLCYLQLTRQLVSCSSDGGIAVWNMDVSRE
EAPQWLESDSCQKCEQPFFWNIKQMWDTKTLGLRQHHCRKCGQAVCGKCSSKRSSYPV
MGFEFQVRVCDSCYDSIKDEDRTSLATFHEGKHNISHMSMDIARGLMVTCGTDRIVKI
WDMTPVVGCSLATGFSPH"
BASE COUNT 1473 a 884 c 989 g 1379 t
ORIGIN
1 agtcgccgcg cgaacatggc ggccgaaatc cactccaggc cgcagagcag ccgcccggtg
61 ctgctgagca agatcgaggg gcaccaggac gccgtcacgg ccgcgctgct catccccaag
121 gaggacggcg tgatcacggc cagcgaggac agaaccatcc gggtatggct gaaaagagac
181 agtggtcaat actggcccag catttaccac acaatggcct ctccttgctc tgctatggct
241 taccatcatg acagcagacg gatatttgtg ggccaggata atggagctgt aatggaattt
301 cacgtttctg aagattttaa taaaatgaac tttatcaaga cctacccagc tcatcagaac
361 cgggtgtctg cgattatctt cagcttggcc acagagtggg tgatcagtac cggccacgac
421 aagtgtgtga gctggatgtg cacgcggagc gggaacatgc tcgggaggca cttcttcacg
481 tcctgggctt cgtgtctgca atatgacttt gacactcagt atgctttcgt tggtgattat
541 tctgggcaga tcaccctgct gaagcttgaa cagaacacgt gttcagtcat cacaaccctc
601 aaaggacatg aaggtagtgt cgcctgcctc tggtgggacc ctattcagcg gttactcttc
661 tcaggagcat ctgacaacag catcatcatg tgggacatcg gaggaaggaa aggccggacg
721 ctgttacttc agggccatca tgacaaggtg cagtcgctgt gctaccttca gctcaccagg
781 cagctcgtct cctgttcctc ggacggcgga attgcagtgt ggaacatgga tgttagcaga
841 gaagaggctc ctcagtggtt ggaaagtgat tcttgtcaga aatgtgagca gccatttttc
901 tggaacataa agcagatgtg ggacaccaag acgctggggc taagacaaca tcactgcagg
961 aaatgcgggc aggctgtctg cgggaagtgc agcagcaagc gctcaagtta cccagtcatg
1021 ggcttcgagt tccaagtccg ggtttgtgat tcttgttacg actccatcaa agatgaagat
1081 cggacttctc tagcgacctt tcatgaagga aaacataaca tttcccacat gtccatggac
1141 attgccaggg gactgatggt gacctgtggg accgaccgca ttgtaaagat ctgggacatg
1201 acacctgtgg tgggctgcag tctggcgact gggttttctc cgcactgatc tgagagctgg
1261 gcagcgtcca cacctaagaa cagcagctcc accaaatgaa gtccctctca cgcagctcca
1321 cagcgctgtc tcgtgaatgg acagtagcca cttacaaaca aatcaacatt tttaaaaaga
1381 aaatgtaaag gtgtgttttg gggcatttgt ggaacttacc catggggact aatatggaaa
1441 aggtctgtcc atagtggttc cctgaagact ggaattactt cagcaaaact tccccatgaa
1501 cagctaatgt gtagtgaaag aatgagctag caaatgagtt ttagcgggga caaaaaatca
1561 aacaaaaaag tgaatgctta gaaccttctc aaagcagtca caagtacaga cacttcactt
1621 agcctagggg gccttccagg gttcttgtgg ctgttgtcag agcaggagct gggggaggga
1681 agacttgttc tctctttctt gaggggtggc attaggaact tacgaaacca gagacctttc
1741 cctatgactt ggcagtatgt gaatatcctc tacacttagt tattgataaa cttcttaaag
1801 agatctgtta ttttcaggta gtgccataat ctgcacttag cattggcttg cttcagttgt
1861 ttctcttccc agccagtatg ccacaggtga actttcgagg ttgtcattaa gtaagttgtg
1921 aaatttctgt aataacaaag gcagtccgca ttcttccctt tcccccaaat tcctagggca
1981 aaactttttt atggtgctgt taacatggga gtcacacaag ccgcctgact ttttctcatt
2041 gccattagta atgactgatg gaaaacccag ccaccactgt gatgcgaaat gatcagtctg
2101 ttgcctgaaa cagcccagtc ctcttaactg aaacagcatt ctacttcttg ttccaagatg
2161 agcctctgca atattctggc aatttaatat accccctaca aaagcactcc acagctttta
2221 cactattttg actttgagtt ataactagta ttattcatgt tttcataaaa agaagttagt
2281 gacccagagc tataatcatc catcaagtct tccacaataa ttcccaactc ataaattgct
2341 ttcctaacaa ctagcaaaag ctattgttca taatggcatt tctaaagctt ttgggcactg
2401 tgtaccagga tgaggaagag aagaaatgag gagcctgtct tttaatattc cagtatttgt
2461 gtgtttgatt ttttttgaca acagtacata tatctatttc tctagggata tggaagtaag
2521 tggagaaggg cctacctttt taaaggacaa atataaaaat agcaacagta tctttgctaa
2581 tcttactaat ggatattgat taaaaaaaaa aaacctcagt actgcatcac tgtgttggga
2641 tcgtaccagg acaatagggt cattccatat gataaaacta aaggactaaa tttgttttat
2701 aatgatgtct tagagggact gaaaagttta aggaggcgat caaactaaaa tgtcttaatg
2761 gctgtgtgac acacgtaagg aaaggaaagg gggtcacgca catcatgtac tggaatgatc
2821 tgcattaaac attgacttgt cttcagaaat aagactgaag ggttttgttg ttccttagag
2881 ttttcgtgtt acatcaccta aagagatttc ttttaaaaac tttctagact ctttgcaaaa
2941 tgtatattac taacatagtt tggaagaaaa attgagtagt ggtaagtttt gttcaagcac
3001 aatgttgaat gttaagcttc ctgtattaat tttagttcag ttaatggttc agcccataca
3061 aaggtgctat cctagggatt ttatgaattc ctgaaaggaa aatagaatat gatcaattcc
3121 ttgccctgtg gaagagtgca gaactgtggt tttgttttcc tttgacttct gtaaaatgtg
3181 accgtttgac atctgtggta gattgaacgg aatatcacag ctgctgagtt tactccatag
3241 ctttcaaacc ttttttattt taagaaattc ttgaaaaacc ctatgttcaa tgggaacata
3301 aagttattat agtgcctcct aaggggttaa tataaatcaa ggaggaagtt tatatttaag
3361 gaagaattgg agtgacgtat cttagaaaag gaaaggctga tgtttccata tagcttgctc
3421 tccgccaggc ctatcatttt tctttttaga gacaaacgtg acaggctagt cttgtctctc
3481 tcatatgcta ggtagcaaat ggggtgatat ttttatagaa gtgggcaaaa attattttct
3541 caattttact gagtaggcac agaagaaaag tacagatagg ctgatggtta ttgccttatt
3601 ttgactgcat ttctcttaaa tggatcattt aaattagttc ttcaagtaac agtttactgg
3661 ttgttccatt cctgaatatg caggctaatt tgtacagata gggattaagg aatacagact
3721 attagagaag atccttatat ttacatctag tatatatgtg gtaaggaaat gccgattctt
3781 cattataaac aagttttaaa attgttcttt cttagttcaa atgatagcaa tacccctata
3841 gcattaggta gaaacaaatt attcattaca tcgtaaatct ctttactatg tcctagctct
3901 gtcctgctac ctaaaggata taaagaaata ttattgctct agaatgtatt actttgttct
3961 cccatgaaag aattcagttt gttagtacct atatttttaa actggtgaaa ctgacccaaa
4021 tatgtaataa ataccatagt agctcagacc caaggagata tttttctaaa atcagttttc
4081 gttaaagtac ttctacttcc gttattggat atggtatctc ctaaagtgta aaaaaaatct
4141 gttactatat agtgataaac catctgctca tcgtaagtgt aaggcttaac aaataagtaa
4201 tacatgctat atttattcaa gtgtctattg cttaattgtt aattgtgagc agatttattg
4261 aatgcctatt ctattttctg cagtttacaa tacaataact ctttgagtaa gttgaagttt
4321 aattgtgcaa caaatttgta ttagagtaca atttaaagtg tttttctcta tagccttttt
4381 tgactgggga agcaaggggt aatgttaatt agtacacttt gttcttgtac tagctatgtt
4441 tctataagat atggtgccct gtgtatccca gagatgctag aaaactgttc tttgctccta
4501 tttgtgggtt ctgtttttgt gggttttttt tttttgagaa aatgtacaca ataaaacatt
4561 ccttgcttgt taaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
4621 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
4681 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//