LOCUS BC040455 1443 bp mRNA linear HUM 19-MAR-2009
DEFINITION Homo sapiens ST6
(alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,
3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2, mRNA
(cDNA clone MGC:22667 IMAGE:4252792), complete cds.
ACCESSION BC040455
VERSION BC040455.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1443)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1443)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-NOV-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 35 Row: g Column: 1
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 5454091
The stop codon of the CDS annotated on this record is located > 55
bases upstream of a splice junction, and therefore the mRNA is
predicted to be subject to nonsense-mediated mRNA decay (NMD).
FEATURES Location/Qualifiers
source 1..1443
/db_xref="H-InvDB:HIT000052390"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:22667 IMAGE:4252792"
/tissue_type="Skin, melanotic melanoma, high MDR."
/clone_lib="NIH_MGC_62"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1443
/gene="ST6GALNAC2"
/gene_synonym="SAITL1"
/gene_synonym="ST6GalNAII"
/gene_synonym="STHM"
/db_xref="GeneID:10610"
/db_xref="HGNC:HGNC:10867"
/db_xref="MIM:610137"
CDS 38..1162
/gene="ST6GALNAC2"
/gene_synonym="SAITL1"
/gene_synonym="ST6GalNAII"
/gene_synonym="STHM"
/codon_start=1
/product="ST6GALNAC2 protein"
/protein_id="AAH40455.1"
/db_xref="GeneID:10610"
/db_xref="HGNC:HGNC:10867"
/db_xref="MIM:610137"
/translation="MGLPRGSFFWLLLLLTAACSGLLFALYFSAVQRYPGPAAGARDT
TSFEAFFQSKASNSWTGKGQACRHLLHLAIQRHPHFRGLFNLSIPVLLWGDLFTPALW
DRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGIL
NGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTS
VPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEASASKFKLLH
PDFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFS
DHYFERKMKPLIFYANHDLSLEAALWRDLHKAGILQLYQR"
BASE COUNT 330 a 432 c 348 g 333 t
ORIGIN
1 gacgtcagcg gaccgggcgc tcgcgggccg gggctgtatg gggctcccgc gcgggtcgtt
61 cttctggctg ctgctcctgc tcacggctgc ctgctcgggg ctcctctttg ccctgtactt
121 ctcggcggtg cagcggtacc cggggccagc ggccggagcc agggacacca catcatttga
181 agcattcttt caatccaagg catcgaattc ttggacagga aagggccagg cctgccgaca
241 cctgcttcac ctggccattc agcggcaccc ccacttccgt ggcctgttca atctctccat
301 tccagtgctg ctgtgggggg acctcttcac cccagcgctc tgggaccgcc tgagccaaca
361 caaagccccg tatggctggc gggggctctc tcaccaagtc atcgcctcca ccctgagcct
421 tctgaacggc tcagagagtg ccaagctgtt tgccccgccc agggacaccc ctccaaagtg
481 tatccggtgt gccgtggtgg gcaacggagg cattctgaat gggtcccgcc agggtcccaa
541 catcgatgcc catgactatg tattcagact caatggagct gtgatcaaag gcttcgagcg
601 cgatgtgggc accaagactt ccttctatgg tttcactgtg aacacgatga agaactccct
661 cgtctcctac tggaatctgg gcttcacctc cgtgccacaa ggacaggacc tgcagtatat
721 cttcatcccc tcagacatcc gcgactatgt gatgctgaga tcggccattc tgggcgtgcc
781 tgtccctgag ggcctagata aaggggacag gccgcacgcc tattttggac cagaagcctc
841 tgccagtaaa ttcaagctgc tacatccgga cttcatcagc tacctgacag aaaggttctt
901 gaaatcaaag ttgattaaca cacattttgg agacctatat atgcctagta ccggggctct
961 catgctgctg acagctttgc atacctgtga ccaggtcagt gcctatggat tcatcacaag
1021 caactactgg aaattttccg accactattt cgaacgaaaa atgaagccat tgatatttta
1081 tgcaaaccac gatctgtccc tggaagctgc cctgtggagg gacctgcaca aggccggcat
1141 ccttcagctg taccagcgct gaccccaatg cactgagccc tttgcttctt caagagttgc
1201 ggccctgatc ctctcaagtg gccaaaagct tttttaactt ttcaatcttc accttccctt
1261 gccaacagag ggcactgggg tgaattcaag attttcatcg aggtctgttc aatataggac
1321 accccagctt gtccttggct catccaagaa ctcttctgta tcaccacctt gtcaccaaca
1381 ggatgatgtc accaggtaat aaaccttcat ccccaaaaaa aaaaaaaaaa aaaaaaaaaa
1441 aaa
//