LOCUS BC039904 3791 bp mRNA linear HUM 25-NOV-2003
DEFINITION Homo sapiens histone deacetylase 4, mRNA (cDNA clone MGC:47583
IMAGE:6067363), complete cds.
ACCESSION BC039904
VERSION BC039904.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3791)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3791)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 82 Row: p Column: 7
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 13259519.
FEATURES Location/Qualifiers
source 1..3791
/db_xref="H-InvDB:HIT000052290"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:47583 IMAGE:6067363"
/tissue_type="Testis, embryonal carcinoma"
/clone_lib="NIH_MGC_92"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3791
/gene="HDAC4"
/gene_synonym="HA6116"
/gene_synonym="HD4"
/gene_synonym="HDAC-A"
/gene_synonym="HDACA"
/gene_synonym="KIAA0288"
/db_xref="GeneID:9759"
/db_xref="MIM:605314"
CDS 396..3314
/gene="HDAC4"
/gene_synonym="HA6116"
/gene_synonym="HD4"
/gene_synonym="HDAC-A"
/gene_synonym="HDACA"
/gene_synonym="KIAA0288"
/codon_start=1
/product="HDAC4 protein"
/protein_id="AAH39904.1"
/db_xref="GeneID:9759"
/db_xref="MIM:605314"
/translation="MLAMKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKG
KESAVASTEVKMKLQEFVLNKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQS
GVSTSYNHPVLGMYDAKDDFPLRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVV
TALKKRPLDVTDSACSSAPGSGPSSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVA
REGSAAPLPLYTSPSLPNITLGLPATGPSAGTAGQQDAERLTLPALQQRLSLFPGTHL
TPYLSTSPLERDGGAAHSPLLQHMVLLEQPPAQAPLVTDWYLSGLGALPLHAQSLVGA
DRVSPSIHKLRQHRPLGRTQSAPLPQNAQALQHLVIQQQHQQFLEKHKQQFQQQQLQM
NKIIPKPSEPARQPESHPEETEEELREHQALLDEPYLDRLPGQKEAHAQAGVQVKQEP
IESDEEEAEPPREVEPGQRQPSEQELLFRQQALLLEQQRIHQLRNYQASMEAAGIPVS
FGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTGLVYDTLMLKHQCTCGSSSSHPEH
AGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHSEAHTLLYGTNPLNRQKLDSK
KLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAVGCVVELVFKVATGELKNGF
AVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKILIVDWDVHHGNGTQQAFY
SDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFTGGLDPPMGDAEYLAA
FRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGYLTKQLMGLAGGRI
VLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVRSMEKVMEIHSK
YWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDEEPMEEEPPL
"
misc_feature 2022..2993
/gene="HDAC4"
/gene_synonym="HA6116"
/gene_synonym="HD4"
/gene_synonym="HDAC-A"
/gene_synonym="HDACA"
/gene_synonym="KIAA0288"
/note="HisDeac1; Region: RPD3 like Histone decetylase
domain"
/db_xref="CDD:LOAD_HisDeac1"
BASE COUNT 866 a 1198 c 1117 g 610 t
ORIGIN
1 ccacgcgtcc ggacgctgga gtggggagaa gcatcatggt tcaacgttca tctgcagaag
61 ccagcggacg cctctgttca acttgtgggt tacctggctc atgagacctt gccggcgagg
121 ctcggcgctt gaacgtctgt gacccagccc tcaccgtccc ggtacttgta tgtgttggtg
181 ggagtttgga gctcgttgga gctatcgttt ccgtggaaat tttgagccat ttcgaatcac
241 ttaaaggagt ggacattgct agcaatgagc tcccaaagcc atccagatgg actttctggc
301 cgagaccagc cagtggagct gctgaatcct gcccgcgtga accacatgcc cagcacgagg
361 cgcagctcca cgagcacatc aagcaacaac aggagatgct ggccatgaag caccagcagg
421 agctgctgga acaccagcgg aagctggaga ggcaccgcca ggagcaggag ctggagaagc
481 agcaccggga gcagaagctg cagcagctca agaacaagga gaagggcaaa gagagtgccg
541 tggccagcac agaagtgaag atgaagttac aagaatttgt cctcaataaa aagaaggcgc
601 tggcccaccg gaatctgaac cactgcattt ccagcgaccc tcgctactgg tacgggaaaa
661 cgcagcacag ttcccttgac cagagttctc caccccagag cggagtgtcg acctcctata
721 accacccggt cctgggaatg tacgacgcca aagatgactt ccctcttagg aaaacagctt
781 ctgaaccgaa tctgaaatta cggtccaggc taaagcagaa agtggccgaa agacggagca
841 gccccctgtt acgcaggaaa gacgggccag tggtcactgc tctaaaaaag cgtccgttgg
901 atgtcacaga ctccgcgtgc agcagcgccc caggctccgg acccagctca cccaacaaca
961 gctccgggag cgtcagcgcg gagaacggta tcgcgcccgc cgtccccagc atcccggcgg
1021 agacgagttt ggcgcacaga cttgtggcac gagaaggctc ggccgctcca cttcccctct
1081 acacatcgcc atccttgccc aacatcacgc tgggcctgcc tgccaccggc ccctctgcgg
1141 gcacggcggg ccagcaggac gccgagagac tcacccttcc cgccctccag cagaggctct
1201 cccttttccc cggcacccac ctcactccct acctgagcac ctcgcccttg gagcgggacg
1261 gaggggcagc gcacagccct cttctgcagc acatggtctt actggagcag ccgccggcac
1321 aagcacccct cgtcacagac tggtatcttt caggcctggg agcactgccc ctccacgcac
1381 agtccttggt tggtgcagac cgggtgtccc cctccatcca caagctgcgg cagcaccgcc
1441 cactggggcg gacccagtcg gccccgctgc cccagaacgc ccaggctctg cagcacctgg
1501 tcatccagca gcagcatcag cagtttctgg agaaacacaa gcagcagttc cagcagcagc
1561 aactgcagat gaacaagatc atccccaagc caagcgagcc agcccggcag ccggagagcc
1621 acccggagga gacggaggag gagctccgtg agcaccaggc tctgctggac gagccctacc
1681 tggaccggct gccggggcag aaggaggcgc acgcacaggc cggcgtgcag gtgaagcagg
1741 agcccattga gagcgatgag gaagaggcag agcccccacg ggaggtggag ccgggccagc
1801 gccagcccag tgagcaggag ctgctcttca gacagcaagc cctcctgctg gagcagcagc
1861 ggatccacca gctgaggaac taccaggcgt ccatggaggc cgccggcatc cccgtgtcct
1921 tcggcggcca caggcctctg tcccgggcgc agtcctcacc cgcgtctgcc accttccccg
1981 tgtctgtgca ggagcccccc accaagccga ggttcacgac aggcctcgtg tatgacacgc
2041 tgatgctgaa gcaccagtgc acctgcggga gtagcagcag ccaccccgag cacgccggga
2101 ggatccagag catctggtcc cgcctgcagg agacgggcct ccggggcaaa tgcgagtgca
2161 tccgcggacg caaggccacc ctggaggagc tacagacggt gcactcggaa gcccacaccc
2221 tcctgtatgg cacgaacccc ctcaaccggc agaaactgga cagtaagaaa cttctaggct
2281 cgctcgcctc cgtgttcgtc cggctccctt gcggtggtgt tggggtggac agtgacacca
2341 tatggaacga ggtgcactcg gcgggggcag cccgcctggc tgtgggctgc gtggtagagc
2401 tggtcttcaa ggtggccaca ggggagctga agaatggctt tgctgtggtc cgcccccctg
2461 gacaccatgc ggaggagagc acgcccatgg gcttttgcta cttcaactcc gtggccgtgg
2521 cagccaagct tctgcagcag aggttgagcg tgagcaagat cctcatcgtg gactgggacg
2581 tgcaccatgg aaacgggacc cagcaggctt tctacagcga ccccagcgtc ctgtacatgt
2641 ccctccaccg ctacgacgat gggaacttct tcccaggcag cggggctcct gatgaggtgg
2701 gcacagggcc cggcgtgggt ttcaacgtca acatggcttt caccggcggc ctggaccccc
2761 ccatgggaga cgctgagtac ttggcggcct tcagaacggt ggtcatgccg atcgccagcg
2821 agtttgcccc ggatgtggtg ctggtgtcat caggcttcga tgccgtggag ggccacccca
2881 cccctcttgg gggctacaac ctctccgcca gatgcttcgg gtacctgacg aagcagctga
2941 tgggcctggc tggcggccgg attgtcctgg ccctcgaggg aggccacgac ctgaccgcca
3001 tttgcgacgc ctcggaagca tgtgtttctg ccttgctggg aaacgagctt gatcctctcc
3061 cagaaaaggt tttacagcaa agacccaatg caaacgctgt ccgttccatg gagaaagtca
3121 tggagatcca cagcaagtac tggcgctgcc tgcagcgcac aacctccaca gcggggcgtt
3181 ctctgatcga ggctcagact tgcgagaacg aagaagccga gacggtcacc gccatggcct
3241 cgctgtccgt gggcgtgaag cccgccgaaa agagaccaga tgaggagccc atggaagagg
3301 agccgcccct gtagcactcc ctcgaagctg ctgttctctt gtctgtctgt ctctgtcttg
3361 aagctcagcc aagaaacttt cccgtgtcac gcctgcgtcc caccgtgggg ctctcttgga
3421 gcacccaggg acacccagcg tgcaacagcc acgggaagcc tttctgccgc ccaggcccac
3481 aggtctcgag acgcacatgc acgcctgggc gtggcagcct cacagggaac acgggacaga
3541 cgccggcgac gcgcagacac acggacacgc ggaagccaag cacactctgg cgggtcccgc
3601 aagggacgcc gtggaagaaa ggagcctgtg gcaacaggcg gccgagctgc cgaattcagt
3661 tgacacgagg cacagaaaac aaatatcaaa gatctaataa tacaaaacaa acttgattaa
3721 aactggtgct taaagtttat tacccacaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3781 aaaaaaaaaa a
//