LOCUS BC039849 1016 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens glutathione peroxidase 4 (phospholipid
hydroperoxidase), mRNA (cDNA clone MGC:48873 IMAGE:5744771),
complete cds.
ACCESSION BC039849
VERSION BC039849.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1016)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1016)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-NOV-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 84 Row: k Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4504106.
FEATURES Location/Qualifiers
source 1..1016
/db_xref="H-InvDB:HIT000095920"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:48873 IMAGE:5744771"
/tissue_type="Brain, adult medulla"
/clone_lib="NIH_MGC_119"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1016
/gene="GPX4"
/gene_synonym="MCSP"
/gene_synonym="PHGPx"
/gene_synonym="snGPx"
/gene_synonym="snPHGPx"
/db_xref="GeneID:2879"
/db_xref="HGNC:HGNC:4556"
/db_xref="MIM:138322"
CDS 108..701
/gene="GPX4"
/gene_synonym="MCSP"
/gene_synonym="PHGPx"
/gene_synonym="snGPx"
/gene_synonym="snPHGPx"
/codon_start=1
/transl_except=(pos:324..326,aa:OTHER)
/product="glutathione peroxidase 4 (phospholipid
hydroperoxidase)"
/protein_id="AAH39849.1"
/db_xref="GeneID:2879"
/db_xref="HGNC:HGNC:4556"
/db_xref="MIM:138322"
/translation="MSLGRLCRLLKPALLCGALAAPGLAGTMCASRDDWRCARSMHEF
SAKDIDGHMVNLDKYRGFVCIVTNVASQXGKTEVNYTQLVDLHARYAECGLRILAFPC
NQFGKQEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGILGNA
IKWNFTKFLIDKNGCVVKRYGPMEEPLVIEKDLPHYF"
BASE COUNT 292 a 284 c 288 g 152 t
ORIGIN
1 gagcgctctg gagggcgtgg ccgtgggaaa ggaggcgcgg aaagccgacg cgcgtccatt
61 ggtcggctgg acgaggggag gagccgctgg ctcccagccc cgccgcgatg agcctcggcc
121 gcctttgccg cctactgaag ccggcgctgc tctgtggggc tctggccgcg cctggcctgg
181 ccgggaccat gtgcgcgtcc cgggacgact ggcgctgtgc gcgctccatg cacgagtttt
241 ccgccaagga catcgacggg cacatggtta acctggacaa gtaccggggc ttcgtgtgca
301 tcgtcaccaa cgtggcctcc cagtgaggca agaccgaagt aaactacact cagctcgtcg
361 acctgcacgc ccgatacgct gagtgtggtt tgcggatcct ggccttcccg tgtaaccagt
421 tcgggaagca ggagccaggg agtaacgaag agatcaaaga gttcgccgcg ggctacaacg
481 tcaaattcga tatgttcagc aagatctgcg tgaacgggga cgacgcccac ccgctgtgga
541 agtggatgaa gatccaaccc aagggcaagg gcatcctggg aaatgccatc aagtggaact
601 tcaccaagtt cctcatcgac aagaacggct gcgtggtgaa gcgctacgga cccatggagg
661 agcccctggt gatagagaag gacctgcccc actatttcta gctccacaag tgtgtggccc
721 cgcccgagcc cctgcccacg cccttggagc cttccaccgg cactcatgac ggcctgcctg
781 caaacctgct ggtggggcag acccgaaaat ccagcgtgca ccccgccgga ggaaggtccc
841 atggcctgct gggcttggct cggcgccccc acccctggct accttgtggg aataaacaga
901 caaattagaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
961 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//