LOCUS BC039835 4024 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens HIR histone cell cycle regulation defective homolog A
(S. cerevisiae), mRNA (cDNA clone MGC:48803 IMAGE:5491361),
complete cds.
ACCESSION BC039835
VERSION BC039835.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4024)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4024)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-NOV-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 84 Row: f Column: 22.
FEATURES Location/Qualifiers
source 1..4024
/db_xref="H-InvDB:HIT000052264"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:48803 IMAGE:5491361"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..4024
/gene="HIRA"
/gene_synonym="DGCR1"
/gene_synonym="TUP1"
/db_xref="GeneID:7290"
/db_xref="HGNC:HGNC:4916"
/db_xref="MIM:600237"
CDS 216..3269
/gene="HIRA"
/gene_synonym="DGCR1"
/gene_synonym="TUP1"
/codon_start=1
/product="HIR histone cell cycle regulation defective
homolog A (S. cerevisiae)"
/protein_id="AAH39835.1"
/db_xref="GeneID:7290"
/db_xref="HGNC:HGNC:4916"
/db_xref="MIM:600237"
/translation="MKLLKPTWVNHNGKPIFSVDIHPDGTKFATGGQGQDSGKVVIWN
MSPVLQEDDEKDENIPKMLCQMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWKRATY
IGPSTVFGSSGKLANVEQWRCVSILRNHSGDVMDVAWSPHDAWLASCSVDNTVVIWNA
VKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSITKPFDE
CGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIEREGWKTNMDFVGHRKAVTVVKF
NPKIFKKKQKNGSSAKPSCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDI
SWTLNGLGILVCSMDGSVAFLDFSQDELGDPLSEEEKSRIHQSTYGKSLAIMTEAQLS
TAVIENPEMLKYQRRQQQQQLDQKSAATREMGSATSVAGVVNGESLEDIRKNLLKKQV
ETRTADGRRRITPLCIAQLDTGDFSTAFFNSIPLSGSLAGTMLSSHSSPQLLPLDSST
PNSFGASKPCTEPVVAASARPAGDSVNKDSMNATSTPAALSPSVLTTPSKIEPMKAFD
SRFTERSKATPGAPALTSMTPTAVERLKEQNLVKELRPRDLLESSSDSDEKVPLAKAS
SLSKRKLELEVETVEKKKKGRPRKDSRLMPVSLSVQSPAALTAEKEAMCLSAPALALK
LPIPSPQRAFTLQVSSDPSMYIEVENEVTVVGGVKLSRLKCNREGKEWETVLTSRILT
AAGSCDVVCVACEKRMLSVFSTCGRRLLSPILLPSPISTLHCTGSYVMALTAAATLSV
WDVHRQVVVVKEESLHSILAGSDMTVSQILLTQHGIPVMNLSDGKAYCFNPSLSTWNL
VSDKQDSLAQCADFRSSLPSQDAMLCSGPLAIIQGRTSNSGRQAARLFSVPHVVQQET
TLAYLENQVAAALTLQSSHEYRHWLLVYARYLVNEGFEYRLREICKDLLGPVHYSTGS
QWESTVVGLRKRELLKELLPVIGQNLRFQRLFTECQEQLDILRDK"
BASE COUNT 929 a 1078 c 1160 g 857 t
ORIGIN
1 ggctgtggtg gcggcggcgg cggccgagcg cgggtggcgg ctgtggcggc ggaggggggc
61 gcgggccggc gatggcgcgg cggccctgag ggcgcggggc gggcggcggc cggagggcgg
121 gcggcgcggg aggaagcggc ggcggtggct ccatggcccg ggcgcgctga gggacccggc
181 gctcgcctca gcccggcggc ggcggcggcc gaacaatgaa gctcctgaag ccgacctggg
241 tcaaccacaa tggcaagccg attttttcag ttgatattca ccctgacggg accaagttcg
301 caactggagg acaagggcag gattctggga aggttgtgat ctggaatatg tctccagtcc
361 tccaggagga tgacgagaag gatgaaaata ttcccaagat gctttgccag atggacaatc
421 acttagcatg tgtgaactgt gtgcggtggt caaacagtgg gatgtattta gcttctgggg
481 gagatgacaa actgattatg gtgtggaagc gggctacgta catcggcccc agcaccgtgt
541 tcggctccag tggtaagctt gccaatgtgg agcagtggcg gtgtgtctct atcctccgga
601 atcattcagg cgatgtgatg gatgtagcat ggtctcccca cgatgcctgg ctagcctcat
661 gcagcgtgga taacactgtc gtcatctgga atgctgtaaa gttcccagaa attctagcta
721 ctctgagagg tcattctggc ttggtcaaag ggttgacatg ggaccctgtt ggtaaataca
781 tagcttctca agctgatgac cgcagcctaa aggtgtggag gacgctggac tggcagttgg
841 agaccagcat caccaagcct tttgatgagt gtggaggaac gacccatgtg ttgcggctca
901 gctggtcacc tgatgggcat tacctggtgt ctgcccatgc catgaacaac tcaggcccca
961 ctgcccagat catcgaacgg gagggatgga agaccaacat ggactttgtt gggcaccgga
1021 aagctgtgac tgtcgtgaaa ttcaacccaa aaatcttcaa aaagaagcag aagaatggga
1081 gttctgcgaa gcctagctgc ccgtactgct gctgtgctgt tggcagcaag gaccgctcgc
1141 tttctgtctg gctcacatgt ctgaaacggc cgctggtggt catccatgaa ctgtttgaca
1201 aatccatcat ggatatttcc tggactctga atgggctggg catcttggta tgctctatgg
1261 acggctctgt ggcattcctc gacttctccc aggatgagct tggcgatccc ctgagcgagg
1321 aggagaagag ccgcattcac cagtccacct atggcaagag cctagccatc atgaccgagg
1381 cccagctctc cacagccgtc attgagaacc ctgagatgct caagtaccag cgaaggcagc
1441 agcagcagca gctggaccag aagagtgctg cgaccaggga gatgggctca gccacctcag
1501 tcgcaggcgt tgtcaacggg gagagtcttg aagatatcag gaagaatctt ttgaagaaac
1561 aagttgagac tcggacagca gatggccgga gaagaatcac gcctctctgc atagcacagc
1621 tggacactgg ggacttctcc acggcattct ttaacagcat ccccctctcg ggctccctgg
1681 cgggcaccat gctctcttct catagcagtc cacagctact gccactggac tccagtaccc
1741 ctaactcctt cggcgcctcg aagccttgca cagagcctgt ggtggctgcc agtgccagac
1801 ctgcaggcga ttctgtcaat aaagacagta tgaatgctac ctctactcct gctgcattgt
1861 caccttctgt gttaacgacc ccgtccaaga tcgaacccat gaaagcgttt gactcccggt
1921 tcacagagcg gtccaaagcc acaccaggtg ctcctgccct gaccagcatg actccgacag
1981 ctgtggaaag gttaaaagag cagaaccttg tgaaagagct gaggccccga gacctcctgg
2041 agagcagcag tgacagcgat gagaaagtcc ctttggctaa ggcttcctca ctgtccaagc
2101 gaaaacttga gcttgaggta gagacagtag agaagaagaa gaaagggcgg cctcggaagg
2161 actctcgtct catgcctgtg tctctgtctg tccagtctcc agctgcccta accgcagaga
2221 aggaggccat gtgtctgtct gcaccagcac ttgcactgaa gctgccaatt ccaagccccc
2281 agagagcatt caccctccag gtcagctccg atccttccat gtacattgag gtggagaatg
2341 aagtgacagt ggtggggggc gtgaagctga gccgcctgaa gtgcaaccgg gaagggaagg
2401 agtgggagac ggtactcacc agccggatcc tcactgctgc gggcagctgt gacgtggtgt
2461 gtgtcgcctg tgaaaaaagg atgctgtcag tgttctccac ctgtggtcgc cgtctcctct
2521 ctcccatcct cctgccatcc ccgatctcta ctttgcattg cacaggctcc tacgtcatgg
2581 cgctcaccgc tgcagccaca ctctctgtct gggatgttca cagacaggtg gttgtggtga
2641 aagaagagtc tctacactcc atcctggcag gaagtgatat gacggtatca cagatcttgc
2701 tgacgcagca tggaatccca gtaatgaacc tgtccgatgg gaaggcgtac tgctttaatc
2761 cgtcactttc cacatggaac ctggtttctg acaagcagga ctcactggct cagtgtgcag
2821 actttaggag cagcctgcca tcccaggacg ccatgctgtg ctcaggaccg ttagccataa
2881 tccagggccg cacctccaac tcgggaaggc aggctgcccg gctcttctcc gtgcctcatg
2941 tggtgcagca agagaccacc ctggcctacc tagagaacca ggtggcagca gcactcaccc
3001 tgcagtccag ccacgagtac cgccattggc tcctcgtcta cgcacggtac ctcgtaaacg
3061 aagggtttga ataccgactt cgagaaatat gcaaggactt actgggtccg gttcactact
3121 ccactggaag ccagtgggag tcaacagtag tgggtctgcg gaagagggag ctgctgaagg
3181 agctgctacc agtcatcggg cagaacctcc gattccagcg cctcttcacc gagtgtcagg
3241 aacagctcga catcctgagg gacaagtagc ctgccccagc ctgccctggc tgcagcaagg
3301 gcagggccac actctcgccg ctgatgacat gcaggaccgc ctctcacctg accaggctgt
3361 agggggagga gacactggca ggagatgtgc tgtcctgcac cagcgccagc ccagctccct
3421 gggcagatgt gccctgtgtc ctgggtctga cattgcctca ggagggggaa gctcatccct
3481 ccctccaagc ccccgatgcg gagctagggc tggagctctg cccaggtgcc ctggggccag
3541 caaggcagtc ccaggcctgc cgtctccagc acggccccaa ggtggacact agcccctgct
3601 gctgcaggcg ccatgctgct tcagcagtga cgattgagcc atttgtgaga gagaatccgg
3661 aagcgttagg tattacagca gactgaccta agacctatgt aaaaggaaag ctgttccaac
3721 acacggacta tttttgtact agaatttgct aacttgtaat attgaatttc ctttggccga
3781 taatcaggat ttccctataa gtcacttgga cattggtcac ttgtaggaaa tttaaactct
3841 aattatgaca gctacactga aaaataattg tactgaaatt aacttgtcta tcttcatttg
3901 gttttaattt ttaaatgttt gtaaaaagag actgttttgg gggaatgggg caaaggggtg
3961 ggcgatttct tttgtaagtg taaaataaat gaacacgcat tgaataccaa aaaaaaaaaa
4021 aaag
//