LOCUS BC039600 3842 bp mRNA linear HUM 30-JAN-2008
DEFINITION Homo sapiens hect domain and RLD 4, mRNA (cDNA clone MGC:48902
IMAGE:5212048), complete cds.
ACCESSION BC039600
VERSION BC039600.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3842)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3842)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-NOV-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 84 Row: d Column: 1
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 37620180.
FEATURES Location/Qualifiers
source 1..3842
/db_xref="H-InvDB:HIT000052222"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:48902 IMAGE:5212048"
/tissue_type="Blood, adult leukocytes"
/clone_lib="NIH_MGC_118"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3842
/gene="HERC4"
/gene_synonym="DKFZP564G092"
/db_xref="GeneID:26091"
/db_xref="HGNC:HGNC:24521"
/db_xref="MIM:609248"
CDS 222..3371
/gene="HERC4"
/gene_synonym="DKFZP564G092"
/codon_start=1
/product="hect domain and RLD 4"
/protein_id="AAH39600.1"
/db_xref="GeneID:26091"
/db_xref="HGNC:HGNC:24521"
/db_xref="MIM:609248"
/translation="MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLR
HTVFVLDDGTVYTCGCNDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDK
GQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFC
WGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNK
FGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGH
NSTSHEINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSN
RKSPFTVKGNWYPYNGQCLPDIDSEEYFCVKRIFSGGDQSFSHYSSPQNCGPPDDFRC
PNPTKQIWTVNEALIQKWLSYPSGRFPVEIANEIDGTFSSSGCLNGSFLAVSNDDHYR
TGTRFSGVDMNAARLLFHKLIQPDHPQISQQVAASLEKNLIPKLTSSLPDVEALRFYL
TLPECPLMSDSNNFTTIAIPFGTALVNLEKAPLKVLENWWSVLEPPLFLKIVELFKEV
VVHLLKLYKIGIPPSERRIFNSFLHTALKVLEILHRVNEKMGQIIQYDKFYIHEVQEL
IDIRNDYINWVQQQAYGMLADIPVTICTYPFVFDAQAKTTLLQTDAVLQMQMAIDQAH
RQNVSSLFLPVIESVNPCLILVVRRENIVGDAMEVLRKTKNIDYKKPLKVIFVGEDAV
DAGGVRKEFFLLIMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSDLFHLIGVICGLAI
YNCTIVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDDIEETFCLNF
TITVENFGATEVKELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHK
VCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELP
LEKKKQFLLFLTGSDRIPILGMKSLKLVIQSTGGGEEYLPVSHTCFNLLDLPKYTEKE
TLRSKLIQAIDHNEGFSLI"
BASE COUNT 1178 a 662 c 832 g 1170 t
ORIGIN
1 tggtgctctc cgccccgctt gcctcccgtt cttccccgcc cgctccatcc gggtcgctga
61 cggctgtctc tggactggac agcagtggcg tccgcttttc tctaaggaac ccgataagaa
121 ctccattttc tgttgatgtg gagacatagg gtacctccaa ctttccgggg tttcagaaga
181 gaatttttta ttgaaactgg aagaccaaaa taattacaag catgttgtgc tggggaaatg
241 catcctttgg gcagctaggt ttgggtggaa ttgatgaaga aattgtacta gagcccagaa
301 aaagtgactt ctttataaat aaaagggtcc gagatgtagg atgtggactc agacatactg
361 tgtttgttct ggatgatgga acagtgtaca catgtggatg taatgatcta ggacagctag
421 gtcatgaaaa atccagaaag aaaccagagc aggttgttgc cctggatgcc caaaatattg
481 tagctgtttc atgtggagaa gctcatacgt tagcgctaaa tgacaaaggc caggtgtatg
541 cttggggtct cgattctgat ggacagcttg gcctggtagg atcagaggaa tgcatcagag
601 tacccagaaa tattaaaagt ttgtcagata tccagattgt acaggttgct tgtggttact
661 atcattcact tgcactttct aaagcaagtg aagtcttctg ttggggacag aataaatatg
721 gccaattggg tttaggtact gactgtaaaa agcaaacttc accgcagctg cttaagtctt
781 tgcttggaat ccctttcatg caagttgcag caggaggagc ccatagtttt gtactcaccc
841 tttctggagc tatctttgga tggggacgca acaagtttgg tcagctaggt cttaatgatg
901 aaaatgatag gtatgttcct aatttactaa agtcactaag atctcagaaa atagtttata
961 tttgttgtgg agaagatcat actgctgctc taaccaagga aggtggagtg tttacttttg
1021 gagctggagg gtatggtcag ttgggccata attctaccag tcatgaaata aacccaagga
1081 aagtttttga acttatggga agcattgtca ctgagattgc ttgtggacgg cagcacactt
1141 ctgcttttgt tccttcatca ggacgaattt actcttttgg gcttggtggt aatgggcagc
1201 tgggaaccgg ttcaacaagc aacaggaaaa gcccctttac tgtaaaagga aattggtacc
1261 cctataatgg gcagtgtcta ccagatattg attctgaaga atatttctgt gtaaaaagaa
1321 ttttctcagg gggagatcaa agcttttcac attactctag tccccagaac tgtgggccac
1381 cagatgactt cagatgtccc aatccgacaa agcagatctg gacagtgaat gaagctctaa
1441 ttcagaaatg gctgagctat ccttctggaa ggtttcctgt ggagatagcc aatgagatag
1501 atggaacgtt ttcttcctct ggttgcctaa atggaagttt tttagctgtt agcaatgatg
1561 atcactatag aacaggtacc agattttcag gggttgatat gaatgctgct aggcttttat
1621 tccacaaact tatacaacct gatcatccgc agatatctca gcaggtggca gctagtttgg
1681 aaaagaatct tattcctaaa ctgactagct ccttacctga tgttgaagca ttgaggtttt
1741 atcttactct accagaatgt cccctgatga gtgattccaa caatttcaca acaatagcaa
1801 ttccctttgg tacagctctt gtgaacctag aaaaggcacc actgaaagta cttgaaaact
1861 ggtggtcagt acttgaacct ccactattcc tcaagatagt agaacttttt aaggaagttg
1921 tggtacatct tttgaaactc tacaagatcg gtattccccc ttctgaaaga agaattttca
1981 acagttttct tcatactgca ttaaaggttt tagaaatact acatagggta aatgagaaaa
2041 tgggacagat tatacagtat gataaatttt atatacatga agtacaagaa ttgatagaca
2101 taagaaatga ttatatcaac tgggtccaac agcaggccta tggaatgttg gcagatatcc
2161 ctgttacaat ctgtacatat ccatttgtat ttgatgccca agcaaaaact actctgttac
2221 agaccgatgc agtcttacag atgcagatgg ctattgatca ggcccacagg cagaatgtct
2281 cctctctttt tctcccagtg attgaatctg tgaatccctg cttaattcta gtggtgcgta
2341 gagaaaatat tgtaggagat gcaatggaag tccttaggaa aacaaagaac atagattaca
2401 agaagccact caaggttata tttgttggag aagatgctgt ggatgcagga ggggtgcgca
2461 aagaattttt cttgctcatc atgagggaat tattggatcc taaatacggc atgtttaggt
2521 attatgaaga ttccaggctc atttggtttt ctgataagac atttgaagac agtgatttgt
2581 tccatttgat tggtgttatc tgtggcttag caatttataa ttgtaccatt gtggacctcc
2641 attttccttt ggctttatat aagaaactac tgaaaaagaa gccatccttg gatgatttga
2701 aagaactaat gcctgatgtt gggagaagca tgcaacagtt actggattat ccagaagatg
2761 acatagagga aacattttgt cttaatttta cgatcacagt tgaaaacttt ggtgcaacag
2821 aagtgaaaga gctggttcta aatggtgcag acacagctgt taacaaacaa aatcggcaag
2881 agtttgtcga tgcttatgtg gattacatat tcaataaatc agtggcttcc ttatttgatg
2941 cttttcatgc gggctttcat aaggtctgtg gaggaaaagt ccttctgctc tttcagccta
3001 atgaactaca agcaatggtc attggaaata caaattatga ttggaaggaa ctggaaaaga
3061 atacagaata caaaggggaa tattgggcag aacatcctac gataaaaatt ttttgggaag
3121 tatttcacga attaccattg gaaaagaaga aacagtttct gttatttttg acaggtagtg
3181 atcgcattcc tattcttggt atgaagagtc tgaaactagt catccagtcc acaggaggtg
3241 gtgaggagta tctcccagtt tcccatactt gttttaatct tctggatctt ccaaaatata
3301 cagaaaaaga aactctacgc tctaaactga tccaagctat tgatcacaat gaaggcttca
3361 gtttaatata actttggagt tataactatt cagtttagtg caaaagcatt aaactatttg
3421 tgtttttctt gtggtgatga attcagcaag gtgacagagg tactattata attcttactt
3481 gcagaatgtt caatctacga gtgttcatgg aagccaaaaa atattaaagg aaaatgaaca
3541 aactgttaat attattgtac agaaccatgg attttttttg accatcttct aataaacata
3601 gcaagtatta tgaatacatt aaagttttac taacatgaat tttaagagtt tgcatatttc
3661 agaaatgatc tggtgtgagt gcatggaaat attgcttaat ttttcttcaa tcattgagtg
3721 aaaaaccttt aactttggcc tgcaatagtc atttgattat tttttcattt tgtaaataat
3781 gttaagtttt gtaataaaat agttatgttc tgaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3841 aa
//