LOCUS BC039152 1460 bp mRNA linear HUM 26-JUN-2007
DEFINITION Homo sapiens hairy and enhancer of split 1, (Drosophila), mRNA
(cDNA clone MGC:21078 IMAGE:4749611), complete cds.
ACCESSION BC039152
VERSION BC039152.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1460)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1460)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-NOV-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: James Cleaver, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 28 Row: n Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 8400709.
FEATURES Location/Qualifiers
source 1..1460
/db_xref="H-InvDB:HIT000052144"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:21078 IMAGE:4749611"
/tissue_type="Skin, squamous cell carcinoma"
/clone_lib="NCI_CGAP_Skn4"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6.1"
gene 1..1460
/gene="HES1"
/gene_synonym="HES-1"
/gene_synonym="HHL"
/db_xref="GeneID:3280"
/db_xref="HGNC:HGNC:5192"
/db_xref="MIM:139605"
CDS 197..1030
/gene="HES1"
/gene_synonym="HES-1"
/gene_synonym="HHL"
/codon_start=1
/product="HES1 protein"
/protein_id="AAH39152.1"
/db_xref="GeneID:3280"
/db_xref="HGNC:HGNC:5192"
/db_xref="MIM:139605"
/translation="MPADIMEKNSSSPVAASVNTTPDKPKTASEHRKSSKPIMEKRRR
ARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALSTDPS
VLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHLANCMTQINAMTYPGQPHPAL
QAPPPPPPGPGGPQHAPFAPPPPLVPIPGGAAPPPGGAPCKLGSQAGEAAKVFGGFQV
VPAPDGQFAFLIPNGAFAHSGPVIPVYTSNSGTSVGPNAVSPSSGPSLTADSMWRPWR
N"
BASE COUNT 429 a 385 c 340 g 306 t
ORIGIN
1 cccccgtcta cctctctcct tggtcctgga acagcgctac tgatcaccaa gtagccacaa
61 aatataataa accctcagca cttgctcagt agttttgtga aagtctcaag taaaagagac
121 acaaacaaaa aattcttttt cgtgaagaac tccaaaaata aaattctcta gagataaaaa
181 aaaaaaaaaa aggaaaatgc cagctgatat aatggagaaa aattcctcgt ccccggtagc
241 agccagtgtc aacacgacac cggataaacc aaagacagca tctgagcaca gaaagtcatc
301 aaagcctatt atggagaaaa gacgaagagc aagaataaat gaaagtctga gccagctgaa
361 aacactgatt ttggatgctc tgaagaaaga tagctcgcgg cattccaagc tggagaaggc
421 ggacattctg gaaatgacag tgaagcacct ccggaacctg cagcgggcgc agatgacggc
481 tgcgctgagc acagacccaa gtgtgctggg gaagtaccga gccggcttca gcgagtgcat
541 gaacgaggtg acccgcttcc tgtccacgtg cgagggcgtt aataccgagg tgcgcactcg
601 gctgctcggc cacctggcca actgcatgac ccagatcaat gccatgacct accccgggca
661 gccgcacccc gccttgcagg cgccgccacc gcccccaccg ggacccggcg gcccccagca
721 cgcgccgttc gcgccgccgc cgccactcgt gcccatcccc gggggcgcgg cgccccctcc
781 cggcggcgcc ccctgcaagc tgggcagcca ggctggagag gcggctaagg tgtttggagg
841 cttccaggtg gtaccggctc ccgatggcca gtttgctttc ctcattccca acggggcctt
901 cgcgcacagc ggccctgtca tccccgtcta caccagcaac agcggcacct ccgtgggccc
961 caacgcagtg tcaccttcca gcggcccctc gcttacggcg gactccatgt ggaggccgtg
1021 gcggaactga gggggctcag gccacccctc ctcctaaact ccccaaccca cctctcttcc
1081 ctccggactc taaacaggaa cttgaatact gggagagaag aggacttttt tgattaagtg
1141 gttactttgt gtttttttaa tttctaagaa gttacttttt gtagagagag ctgtattaag
1201 tgactgacca tgcactatat ttgtatatat tttatatgtt catattggat tgcgcctttg
1261 tattataaaa gctcagatga catttcgttt tttacacgag atttcttttt tatgtgatgc
1321 caaagatgtt tgaaaatgct cttaaaatat cttcctttgg ggaagtttat ttgagaaaat
1381 ataataaaag aaaaaagtaa aggcaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1441 aaaaaaaaaa aaaaaaaaaa
//