LOCUS BC039007 2353 bp mRNA linear HUM 28-JUL-2005
DEFINITION Homo sapiens fms-related tyrosine kinase 1 (vascular endothelial
growth factor/vascular permeability factor receptor), mRNA (cDNA
clone MGC:47768 IMAGE:5722772), complete cds.
ACCESSION BC039007
VERSION BC039007.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2353)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2353)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-NOV-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Invitrogen
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 82 Row: h Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 32306519.
FEATURES Location/Qualifiers
source 1..2353
/db_xref="H-InvDB:HIT000052114"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:47768 IMAGE:5722772"
/tissue_type="Ovary, pooled from 3 adults"
/clone_lib="NIH_MGC_125"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2353
/gene="FLT1"
/gene_synonym="VEGFR1"
/db_xref="GeneID:2321"
/db_xref="MIM:165070"
CDS 237..2300
/gene="FLT1"
/gene_synonym="VEGFR1"
/codon_start=1
/product="FLT1 protein"
/protein_id="AAH39007.1"
/db_xref="GeneID:2321"
/db_xref="MIM:165070"
/translation="MVSYWDTGVLLCALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQ
AGQTLHLQCRGEAAHKWSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHT
GFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRV
TSPNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKT
NYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRA
SVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFI
TVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTRGYSLII
KDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQ
ILTCTAYGIPQPTIKWFWHPCNHNHSEARCDFCSNNEESFILDADSNMGNRIESITQR
MAIIEGKNKMASTLVVADSRISGIYICIASNKVGTVGRNISFYITDVPNGFHVNLEKM
PTEGEDLKLSCTVNKFLYRDVTWILLRTVNNRTMHYSISKQKMAITKEHSITLNLTIM
NVSLQDSGTYACRARNVYTGEEILQKKEITIRGEHCNKKAVFSRISKFKSTRNDCTTQ
SNVKH"
BASE COUNT 747 a 534 c 539 g 533 t
ORIGIN
1 gctcctcccc ggcagcggcg gcggctcgga gcgggctccg gggctcgggt gcagcggcca
61 gcgggcgcct ggcggcgagg attacccggg gaagtggttg tctcctggct ggagccgcga
121 gacgggcgct cagggcgcgg ggccggcggc ggcgaacgag aggacggact ctggcggccg
181 ggtcgttggc cgcggggagc gcgggcaccg ggcgagcagg ccgcgtcgcg ctcaccatgg
241 tcagctactg ggacaccggg gtcctgctgt gcgcgctgct cagctgtctg cttctcacag
301 gatctagttc aggttcaaaa ttaaaagatc ctgaactgag tttaaaaggc acccagcaca
361 tcatgcaagc aggccagaca ctgcatctcc aatgcagggg ggaagcagcc cataaatggt
421 ctttgcctga aatggtgagt aaggaaagcg aaaggctgag cataactaaa tctgcctgtg
481 gaagaaatgg caaacaattc tgcagtactt taaccttgaa cacagctcaa gcaaaccaca
541 ctggcttcta cagctgcaaa tatctagctg tacctacttc aaagaagaag gaaacagaat
601 ctgcaatcta tatatttatt agtgatacag gtagaccttt cgtagagatg tacagtgaaa
661 tccccgaaat tatacacatg actgaaggaa gggagctcgt cattccctgc cgggttacgt
721 cacctaacat cactgttact ttaaaaaagt ttccacttga cactttgatc cctgatggaa
781 aacgcataat ctgggacagt agaaagggct tcatcatatc aaatgcaacg tacaaagaaa
841 tagggcttct gacctgtgaa gcaacagtca atgggcattt gtataagaca aactatctca
901 cacatcgaca aaccaataca atcatagatg tccaaataag cacaccacgc ccagtcaaat
961 tacttagagg ccatactctt gtcctcaatt gtactgctac cactcccttg aacacgagag
1021 ttcaaatgac ctggagttac cctgatgaaa aaaataagag agcttccgta aggcgacgaa
1081 ttgaccaaag caattcccat gccaacatat tctacagtgt tcttactatt gacaaaatgc
1141 agaacaaaga caaaggactt tatacttgtc gtgtaaggag tggaccatca ttcaaatctg
1201 ttaacacctc agtgcatata tatgataaag cattcatcac tgtgaaacat cgaaaacagc
1261 aggtgcttga aaccgtagct ggcaagcggt cttaccggct ctctatgaaa gtgaaggcat
1321 ttccctcgcc ggaagttgta tggttaaaag atgggttacc tgcgactgag aaatctgctc
1381 gctatttgac tcgtggctac tcgttaatta tcaaggacgt aactgaagag gatgcaggga
1441 attatacaat cttgctgagc ataaaacagt caaatgtgtt taaaaacctc actgccactc
1501 taattgtcaa tgtgaaaccc cagatttacg aaaaggccgt gtcatcgttt ccagacccgg
1561 ctctctaccc actgggcagc agacaaatcc tgacttgtac cgcatatggt atccctcaac
1621 ctacaatcaa gtggttctgg cacccctgta accataatca ttccgaagca aggtgtgact
1681 tttgttccaa taatgaagag tcctttatcc tggatgctga cagcaacatg ggaaacagaa
1741 ttgagagcat cactcagcgc atggcaataa tagaaggaaa gaataagatg gctagcacct
1801 tggttgtggc tgactctaga atttctggaa tctacatttg catagcttcc aataaagttg
1861 ggactgtggg aagaaacata agcttttata tcacagatgt gccaaatggg tttcatgtta
1921 acttggaaaa aatgccgacg gaaggagagg acctgaaact gtcttgcaca gttaacaagt
1981 tcttatacag agacgttact tggattttac tgcggacagt taataacaga acaatgcact
2041 acagtattag caagcaaaaa atggccatca ctaaggagca ctccatcact cttaatctta
2101 ccatcatgaa tgtttccctg caagattcag gcacctatgc ctgcagagcc aggaatgtat
2161 acacagggga agaaatcctc cagaagaaag aaattacaat cagaggtgag cactgcaaca
2221 aaaaggctgt tttctctcgg atctccaaat ttaaaagcac aaggaatgat tgtaccacac
2281 aaagtaatgt aaaacattaa aggactcatt aaaaagtaaa aaaaaaaaaa aaaaaaaaaa
2341 aaaaaaaaaa aaa
//