LOCUS BC038957 4363 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens transducer of ERBB2, 2, mRNA (cDNA clone MGC:47645
IMAGE:5786640), complete cds.
ACCESSION BC038957
VERSION BC038957.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4363)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4363)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-NOV-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 82 Row: m Column: 7
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 56682970.
FEATURES Location/Qualifiers
source 1..4363
/db_xref="H-InvDB:HIT000052094"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:47645 IMAGE:5786640"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_71"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..4363
/gene="TOB2"
/gene_synonym="TOB4"
/gene_synonym="TOBL"
/db_xref="GeneID:10766"
/db_xref="HGNC:HGNC:11980"
/db_xref="MIM:607396"
CDS 481..1515
/gene="TOB2"
/gene_synonym="TOB4"
/gene_synonym="TOBL"
/codon_start=1
/product="transducer of ERBB2, 2"
/protein_id="AAH38957.1"
/db_xref="GeneID:10766"
/db_xref="HGNC:HGNC:11980"
/db_xref="MIM:607396"
/translation="MQLEIKVALNFIISYLYNKLPRRRADLFGEELERLLKKKYEGHW
YPEKPLKGSGFRCVHIGEMVDPVVELAAKRSGLAVEDVRANVPEELSVWIDPFEVSYQ
IGEKGAVKVLYLDDSEGCGAPELDKEIKSSFNPDAQVFVPIGSQDSSLSNSPSPSFGQ
SPSPTFIPRSAQPITFTTASFAATKFGSTKMKKGGGAASGGGVASSGAGGQQPPQQPR
MARSPTNSLLKHKSLSLSMHSLNFITANPAPQSQLSPNAKEFVYNGGGSPSLFFDAAD
GQGSGTPGPFGGSGAGTCNSSSFDMAQVFGGGANSLFLEKTPFVEGLSYNLNTMQYPS
QQFQPVVLAN"
BASE COUNT 1000 a 1199 c 1111 g 1053 t
ORIGIN
1 ccacgcgtcc gggcgcggga aggtgcgggt tgttggctga ggcaagccgt ggctcgggcg
61 acgcggggcc aggagggcag gaccgtctgc cggcgacagc ccataccgtc tgccgttgcg
121 cgacacgaac caccctccga tccgccatcc ccgcgtcgtc gccgctagtc cgcccgcccg
181 ccctcgggcc ccccgctgcc gagcccgacc tcctaagagc tgaaagaaat tattgagagt
241 catagtccat agccccctgc ttcgtccccc aaccctcaac gacgaaaagg acttcggtcc
301 cctggcccgg cgacgcccgg gaaggaaagg agagcgacct ccgccccgcg ctcaggccac
361 cctggaggga gaagccgccc cgcggccggt agagcgcccc gccgccgcgg agacccgaag
421 ccgcctggag cccaaggctg tacacgtgcc ctgtgctgat tctctgccta ggaaaggacc
481 atgcagctag agatcaaagt ggccctgaac ttcatcatct cctacttgta caacaagctg
541 ccccggcgcc gggcagacct gtttggggag gagctagagc ggcttttgaa aaagaaatat
601 gaaggccact ggtaccctga gaagccactg aaaggctctg gcttccgctg tgttcacatt
661 ggggagatgg tggaccccgt ggtggagctg gccgccaagc ggagtggcct ggcagtggaa
721 gatgtgcggg ccaatgtgcc tgaggagctg agtgtctgga ttgatccctt tgaggtgtcc
781 taccagattg gtgagaaggg agctgtgaaa gtgctgtacc tggatgacag tgagggttgc
841 ggtgccccag agctggacaa ggagatcaag agcagcttca accctgacgc ccaggtgttc
901 gtgcccattg gcagccagga cagctccctg tccaactccc catcgccatc ctttggccag
961 tcacccagcc ctaccttcat tccccgctcc gctcagccca tcaccttcac caccgcctcc
1021 ttcgctgcca ccaaatttgg ctccactaag atgaagaagg ggggcggggc agcaagtggt
1081 gggggtgtag ccagcagtgg ggcgggtggc cagcagccac cacagcagcc tcgcatggcc
1141 cgctcaccca ccaacagcct gctgaagcac aagagcctct ctctgtctat gcattcactg
1201 aacttcatca cggccaaccc ggcccctcag tcccagctct cacccaatgc caaggagttc
1261 gtgtacaacg gtggtggctc acccagcctc ttctttgatg cggccgatgg ccagggcagc
1321 ggcaccccag gcccgtttgg aggcagtggg gctggcacct gcaacagcag cagctttgac
1381 atggcccagg tatttggagg tggtgccaac agcctcttcc tggagaagac accctttgtg
1441 gaaggcctca gctacaacct gaacaccatg cagtatccca gccagcagtt ccagcccgtg
1501 gtgctggcca actgaccatc tacctgcccg tggggccagg agcacccaag accacagaaa
1561 agagaaagga aaggccaaaa aaaagaggaa aagaaaaatg tacaaaaaga ttttcgatct
1621 tctcactctt acttctagaa aaaagatcca gcccaggcac ggaatgggag ggccctgcaa
1681 agcacccaag tgtgtttcac tcacccctta ccgctcgccc accggcctgt gatttatttg
1741 gttggtttgg gttttatatt tctttttctt tttttttttt cttacatgta gttttctata
1801 taacatcttt aatgagtggc ttcctgtgct aagaatggtc cagatgtgaa ctgctgctcc
1861 ctgctcctcc cttcctcctt cacactccta gtttaggatt gatgtgtcca agctcatagg
1921 gaagaaagag ctgcagctgg agcctgaccc tccctggaac agggagaggc tggcccgtgt
1981 cactgcctct gtcacccagc tatcctcgca ctcaaagcca tccaacctca gcaggccttc
2041 tcgggccctg ccacctgaat aggtctgacc ccagtcccca ctccctttca ggctgggcca
2101 cagggagttg ctggctggcc acttgacacc ctccccctgg agctgatgtc tgtgactaca
2161 gggagattag cacttcgtct agtgaaactc ctttcatctc tgtcctatgg ccccacccca
2221 ccattccctc taggcccaga ccatcatcat ggccctggcc attgatgtgt atgggctttc
2281 tttccctcat gcagcccctt cttccccagg ctggatgttg tgggtaggga ggggtgtgtg
2341 tgtgtgtatt tggtttgctg tcctttttta aaggattcca agccatgtga aacttccctt
2401 ctggatgtga ttctgggtcg caagtcctta tttatatgtg aggctgggga atgggctggg
2461 ggtattggca gtccttttgc agggcagtgt gtgtggtggg gtgacaccgc tgtggcttag
2521 cccaagacac tcccagagga aaacactgca gaaggaactg gtttgcagac tgtggaagga
2581 tctgcagttt tgtttttgac caaaaaaata ataataagtt agctctgaag ggcagaggga
2641 atacccaagc ccctgatgcc tatgagaagt ccctggactt caaccctcct gttgtttggc
2701 cttagcccag agggagctgc tcacctgagc acccttgggg gtgggcagag aggcagggtg
2761 ggattttaga gttagtgtct gtgcgggggc agccctgagc ctggagttga gactttgggg
2821 tctcttagtt tggaggtgtt gagtgcattt gtgcccctgc ctggttgaga gcttcttggt
2881 acctcttgcc accccttctc actgccctga cccaacccca ctggaccttg atgctgcgag
2941 gagtggtgtc ctgacggact cagcactccc gcctgatgta ttggatcata ggagagcact
3001 tgctctcctg cctctgccag gagagggctt gttcctccaa ctctaggagg ccaggcaagc
3061 atggacagga gccaagggag cagggtcatt aactttttct tctttgcaaa gtgggcactt
3121 gccatcaggg tcccaatcac cagaaagcac caaagcccct ggcaccccac ccactccatc
3181 ctacccaggg accccaagta ggcaactgtt atggcagtgg gtccagccca ggccagcact
3241 gccagcctcc tctccctgca gtaggcacca gctctacctc ccccggcagg caatgtcctg
3301 gcttctcagc ccagcaccat ctgttcccct agacttctca ggggccagcc cagtctgggc
3361 caccctttgt ttccctcatc ctcggctccc acacaggtga cagacccagc agatagcttc
3421 tctctgggaa aggttggatg ctgccttaca tccccttcta gccctcctcc catccacaca
3481 cacaggcacc cacccacacc aggtcggctt gtttctcaca tgtagggaga gaggggagac
3541 caaccccttt gtgtcttttg aaatacgaag aaaaatgtgt gttcaggagc atgactccag
3601 tgctgcgctc ttgggcctag ttcagtctgt cttgtctcaa atctaggcat ttttgcttca
3661 attttatttt ttttaagaat acaaaaacag aaatctgcac taatttacct ggtttcgtag
3721 gaaaactttt ttttattttt tacatttttt ggtgtccgtt tgtattgaat aatttgctac
3781 atttgtaaaa tgtaagaggt atataatata tgtatatttc taacgtaaaa aacataattt
3841 ttttcttttc aagatttttt cttaaaaaga tgagagaaac atattttttc aggaaaaaca
3901 aactttaaaa aaaaaagagg agaaataaaa ccttttctcc cctttcccca tcctctatct
3961 atccctcttt cccaggaaca aatcaaaagg tggattatct tctgaagaat ggaaactgtt
4021 agtccagaat gatgtctttt tctcaatgca gtgagttata gattctctag ttttctccct
4081 agggatggga agggggcatt gaggcaagcc tggagaggag cccggggagc agggtcatga
4141 acttttttct ttagtgaagg aggaatacaa tcaagggttt tgtattcaga atgttgtgca
4201 atattttgga atgggacatt ggtgtgttta gagattttag tttaaaaaca aaacaaaaag
4261 attgatcaaa tctgtacagt ttctattgtt ccagattttt ttaagtttgt attaaaagca
4321 tgatccataa taaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//