LOCUS BC038953 1851 bp mRNA linear HUM 07-OCT-2003
DEFINITION Homo sapiens component of oligomeric golgi complex 3, mRNA (cDNA
clone MGC:47545 IMAGE:5756412), complete cds.
ACCESSION BC038953
VERSION BC038953.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1851)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1851)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (01-NOV-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 82 Row: k Column: 9
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 14591930.
FEATURES Location/Qualifiers
source 1..1851
/db_xref="H-InvDB:HIT000052093"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:47545 IMAGE:5756412"
/tissue_type="Blood, adult leukocytes"
/clone_lib="NIH_MGC_118"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1851
/gene="COG3"
/gene_synonym="SEC34"
/db_xref="GeneID:83548"
/db_xref="MIM:606975"
CDS 33..1367
/gene="COG3"
/gene_synonym="SEC34"
/codon_start=1
/product="COG3 protein"
/protein_id="AAH38953.1"
/db_xref="GeneID:83548"
/db_xref="MIM:606975"
/translation="MAEAALLLLPEAAAERDAREKLALWDRRPDTTAPLTDRQTDSVL
ELKAAAENLPVPAELPIEDLCSLTSQSLPIELTSVVPESTEDILLKGFTSLGMEEERI
ETAQQFFSWFAKLQTQMDQDEGTKYRQMRDYLSGFQEQCDAILNDVNSALQHLESLQK
QYLFVSNKTGTLHEACEQLLKEQSELVDLAENIQQKLSYFNELETINTKLNSPTLSVN
SDGFIPMLAKLDDCITYISSHPNFKDYPIYLLKFKQCLSKALHLMKTYTVNTLQTLTS
QLLKRDPSSVPNADNAFTLFYVKFRAAAPKVRTLIEQIELRSEKIPEYQQLLNDIHQC
YLDQRELLLGPSIACTVAELTSQNNRDHCALVRSGCAFMVHVCQDEHQLYNEFFTKPT
SKLDELLEKLCVSLYDVFRPLIIHVIHLETLSELCGILKNEVLEDHVQNNGK"
misc_feature 399..878
/gene="COG3"
/gene_synonym="SEC34"
/note="Region: Sec34-like family. Sec34 and Sec35 form a
sub-complex, in a seven protein complex that includes Dor1
(PFAM:PF04124). This complex is thought to be important
for tether vesicles to the Golgi"
/db_xref="CDD:pfam04136"
BASE COUNT 598 a 350 c 383 g 520 t
ORIGIN
1 cgctgctgct gaaggccgcg agggcggcgg cgatggcgga ggcggcgctg ttgctgctgc
61 ctgaggcggc ggcggagcgg gacgctaggg aaaagctggc tctctgggat cggagaccgg
121 acacgacggc gccgctgacc gacaggcaga cggactcggt attggagctg aaggcggcgg
181 cagagaactt gccggtgcca gctgagcttc caattgaaga cttgtgcagt ttaacatccc
241 agtcactgcc cattgaactg acttcagtag tgcctgaatc tacagaagac attctcttga
301 agggcttcac ttccttagga atggaagaag aaagaattga aaccgcacag cagtttttct
361 catggtttgc aaagctgcaa actcagatgg atcaagatga aggaactaaa tatagacaga
421 tgagggatta cttgtctggg tttcaggagc agtgtgatgc tatattgaat gatgtaaaca
481 gtgctcttca gcatctggag tctttgcaga aacagtatct ttttgtgtcc aataagacag
541 gaaccctaca tgaagcctgt gaacagctcc taaaagaaca gtcggaactt gttgatctgg
601 ctgaaaacat tcaacaaaag ctttcctatt ttaacgaatt ggaaactatt aacacaaaat
661 tgaattcccc tacattgtcg gtgaatagtg acggatttat acctatgctg gccaagttag
721 atgattgtat aacatatatc tcatctcatc ctaattttaa agattatccc atatatttgc
781 tgaagtttaa acagtgtctt tctaaagctt tgcacctcat gaagacatat actgtgaaca
841 cactacagac cctcacaagt cagttactga aaagggatcc ttcatctgta cctaatgcag
901 acaatgcctt cacattattt tatgtgaaat ttcgagctgc tgcccccaaa gtcagaactc
961 ttattgaaca aatagaactg cggtctgaaa aaatacctga ataccaacaa ctgctaaatg
1021 atatccacca gtgttacctt gatcagcggg agctcctttt gggccctagt attgcttgca
1081 ctgttgcaga gttaaccagc caaaataata gagatcactg tgccttggtt cgtagtggct
1141 gtgccttcat ggttcatgtc tgccaggatg aacaccaact ttacaatgaa tttttcacaa
1201 aaccaacatc aaaattagat gagcttttgg agaaactgtg tgtgtcattg tatgatgtct
1261 tcaggccatt gatcattcat gttattcact tagagactct gtcggaactt tgtgggattc
1321 ttaaaaatga agtgcttgaa gatcatgtgc agaacaatgg taaatgagta gaaatgatca
1381 ttttaagtta tatcactggc tcaatgaatt tgaaaaaaaa ataagtgctt cttccctcac
1441 cccactaaat agataaattt aatatttttg aagcttggct tgatgcctta ccccttcttg
1501 aatgaagttg caccttattc tgtcactaaa gacacaatca gatagggaaa gaatcttaaa
1561 atctgggtaa aattagtaat aaaataatta tagtcagttt tctttctggc atctggaatc
1621 cagatagaac acatcgttac ttttgggtta ggcatttcta gcacactgtt accagaatac
1681 aaaatacata aataaataat tgaatatatt gtatactttt gattaaaaaa caggaattgt
1741 ttttgtgtat attcataata atagttgatc tgttttgaaa ttacaaataa agaaaagcgg
1801 ttctctggaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
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