LOCUS BC038447 4735 bp mRNA linear HUM 07-OCT-2003
DEFINITION Homo sapiens coatomer protein complex, subunit alpha, mRNA (cDNA
clone MGC:45155 IMAGE:5533230), complete cds.
ACCESSION BC038447
VERSION BC038447.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4735)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4735)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (04-OCT-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 69 Row: j Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 6996002.
FEATURES Location/Qualifiers
source 1..4735
/db_xref="H-InvDB:HIT000052037"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:45155 IMAGE:5533230"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_71"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..4735
/gene="COPA"
/gene_synonym="HEP-COP"
/db_xref="GeneID:1314"
/db_xref="MIM:601924"
CDS 90..3791
/gene="COPA"
/gene_synonym="HEP-COP"
/codon_start=1
/product="COPA protein"
/protein_id="AAH38447.1"
/db_xref="GeneID:1314"
/db_xref="MIM:601924"
/translation="MLTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLI
DKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFH
HEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVR
VWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMP
LIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVW
DMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERPAYAVHGNMLH
YVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTRASNLENSTYD
LYTIPKDADSQNPDAPEGKRSSGLTAVWVARNRFAVLDRMHSLLIKNLKNEITKKVQV
PNCDEIFYAGTGNLLLRDADSITLFDVQQKRTLASVKISKVKYVIWSADMSHVALLAK
HEHSCPLPLTAIVICNRKLDALCNIHENIRVKSGAWDESGVFIYTTSNHIKYAVTTGD
HGIIRTLDLPIYVTRVKGNNVYCLDRECRPRVLTIDPTEFKFKLALINRKYDEVLHMV
RNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNC
WEKLGEVALLQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMMKIAEIRKDMSG
HYQNALYLGDVSERVRILKNCGQKSLAYLTAATHGLDEEAESLKETFDPEKETIPDID
PNAKLLQPPAPIMPLDTNWPLLTVSKGFFEGTIASKGKGGALAADIDIDTVGTEGWGE
DAELQLDEDGFVEATEGLGDDALGKGQEEGGGWDVEEDLELPPELDISPGAAGGAEDG
FFVPPTKGTSPTQIWCNNSQLPVDHILAGSFETAMRLLHDQVGVIQFGPYKQLFLQTY
ARGRTTYQALPCLPSMYGYPNRNWKDAGLKNGVPAVGLKLNDLIQRLQLCYQLTTVGK
FEEAVEKFRSILLSVPLLVVDNKQEIAEAQQLITICREYIVGLSVETERKKLPKETLE
QQKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLELGPKPEV
AQQTRKILSACEKNPTDAYQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYSPE
FKGQICRVTTVTEIGKDVIGLRISPLQFR"
misc_feature 1101..2456
/gene="COPA"
/gene_synonym="HEP-COP"
/note="Coatomer_WDAD; Region: Coatomer WD associated
domain"
/db_xref="CDD:pfam04053"
BASE COUNT 1294 a 1109 c 1147 g 1185 t
ORIGIN
1 ccacgcgtcc gcgctgacgt ggaggcgtcc gaagggcagc agggtgtgtc ggggctcgga
61 ttaagacatc ggagtcggag acctgagaga tgttaaccaa attcgagacc aagagcgcgc
121 gggtcaaagg gctcagcttt caccccaaaa gaccttggat cctgactagt ttacataatg
181 gggtcatcca gttatgggac tatcggatgt gcactctcat tgacaagttt gatgaacatg
241 atggtccagt gcgaggcatt gacttccata agcagcagcc actgttcgtc tctggaggag
301 atgactataa gattaaggtt tggaattaca agcttcggcg ctgtcttttc acattgcttg
361 ggcacttaga ttatattcgc accacgtttt ttcatcatga atatccctgg attctgagtg
421 cctccgatga tcagaccatc cgagtgtgga attggcaatc tagaacctgt gtttgtgtgt
481 taacagggca caaccattat gtgatgtgtg ctcagttcca ccccacagaa gacttggtag
541 tatcagccag cctggaccag actgtgcgcg tttgggatat ttctggtctg aggaaaaaaa
601 acctgtcccc tggtgcggtg gaatcggatg tgagaggaat aactggggtt gatctatttg
661 gaactacaga tgcagtggtg aagcatgtac tagagggtca cgatcgtgga gtaaactggg
721 ctgccttcca ccccactatg ccccttattg tatctggggc agatgatcgt caagtgaaga
781 tctggcgcat gaatgaatca aaggcatggg aggttgatac ctgccggggc cattacaaca
841 atgtatcttg tgccgtcttc caccctcgcc aagagttgat cctcagcaat tctgaggaca
901 agagtattcg agtctgggat atgtctaagc ggactggggt tcagactttc cgcagagacc
961 atgatcgttt ctgggtccta gctgctcacc ctaaccttaa cctctttgca gcaggccatg
1021 atggtggtat gattgtgttt aagctggaac gggaacggcc agcctatgct gttcatggca
1081 atatgctaca ctatgtcaag gaccgattct tacgacagct ggatttcaac agctccaaag
1141 atgtagctgt gatgcagttg cggagtggtt ccaagtttcc agtattcaat atgtcataca
1201 atccagcaga aaatgcagtc ctgctttgta caagagctag caatctagag aatagtacct
1261 atgacctgta caccatccct aaagatgctg actcccagaa tcctgatgcg cctgaaggga
1321 aacgatcctc aggcctgaca gccgtttggg tcgctcgaaa tcggtttgct gtcctagatc
1381 ggatgcattc gcttctgatc aagaatctga agaatgagat caccaaaaag gtacaggtgc
1441 ccaactgtga tgagatcttc tatgctggca caggcaatct cctgcttcga gatgcggact
1501 ctatcacact ctttgacgta cagcagaagc ggactctggc atctgtgaag atttctaaag
1561 tgaaatacgt tatctggtca gcagacatgt cacatgtagc actactagcc aaacacgaac
1621 actcatgccc tttgcctctt acagccattg tgatctgtaa ccgcaaactg gatgctttat
1681 gtaacattca tgagaacatt cgtgtcaaga gtggggcctg ggatgagagt ggggtattta
1741 tctataccac aagcaaccac atcaaatatg ctgtcaccac tggggaccac gggatcattc
1801 gaactctgga tttacccatc tatgtcacac gggtgaaggg caacaatgta tactgcctag
1861 acagggagtg tcgtccccgg gtactcacca ttgatcccac tgagttcaaa ttcaagctgg
1921 ccctgatcaa cagaaaatat gatgaggtac tgcacatggt gaggaatgcc aaactagttg
1981 gccagtctat tattgcttat ctccagaaga agggctatcc tgaagtggca ctgcattttg
2041 tcaaggatga gaaaactcgc tttagtctgg cactggagtg tggaaacatt gagattgctc
2101 tggaagcagc caaagcactg gatgacaaga actgctggga aaagctggga gaagtggccc
2161 tgctgcaggg gaaccaccag attgtggaaa tgtgctatca gcgtaccaaa aactttgaca
2221 aactttcctt cctgtatctt atcactggca acttagaaaa acttcgcaag atgatgaaga
2281 ttgctgagat cagaaaggac atgagtggcc actatcagaa tgccctatac ctgggtgatg
2341 tgtcagagcg tgtgcggatc ctgaagaact gtggacagaa gtccctggcc tatctcacag
2401 ctgctaccca tggcttagat gaagaagctg agagcctaaa ggagacattt gacccagaga
2461 aggagacaat cccagacatt gaccctaatg ccaagctgct ccagccacct gcacctatca
2521 tgccattgga taccaattgg cctttattga ctgtatccaa aggatttttt gaaggcacca
2581 ttgccagcaa agggaaggga ggagcactgg ctgctgacat tgacattgac actgttggta
2641 cagagggctg gggagaggat gcagagctgc agttggatga agatgggttt gtggaggcta
2701 cagaaggttt gggggatgat gctcttggca agggacagga agaaggaggt ggctgggatg
2761 tagaagaaga tctggagctc cctcctgagc tggatatatc ccctggggca gctggtgggg
2821 ctgaagatgg tttctttgtg cccccaacca agggaacaag tccaactcag atctggtgta
2881 ataactctca gcttccagtt gatcacatcc tggcaggctc tttcgaaaca gccatgcggc
2941 tccttcatga ccaagtaggg gtaatccagt ttggccccta caagcaactg ttcctacaga
3001 catacgcccg aggccgcaca acctatcagg ctctgccctg cctaccctcc atgtatggct
3061 atcctaatcg caactggaag gatgcagggc tgaagaatgg tgtaccagct gtgggcctga
3121 agcttaatga cctcatccaa cggttgcagc tgtgctacca gctcaccaca gttggcaaat
3181 ttgaggaggc tgtggaaaaa ttccgttcca tccttctcag tgtgccactt cttgttgtgg
3241 acaataaaca agagattgca gaggcccagc agctcatcac catttgccgt gagtacattg
3301 tgggtttgtc cgtggagaca gaaaggaaga agctgcccaa agagactcta gaacagcaga
3361 agcgcatctg tgagatggca gcctatttca cccactcaaa cctgcagcct gtgcacatga
3421 tcctggtgct gcgtacagcc ctcaatctgt tcttcaagct caagaacttc aagacagctg
3481 ccacctttgc tcggcgccta ctagaactcg ggcccaagcc tgaggtggcc caacagaccc
3541 gaaaaatcct gtctgcctgt gagaagaatc ccacagatgc ctaccagctc aattatgaca
3601 tgcacaaccc ctttgacatt tgtgctgcat catatcggcc catctaccgt ggaaagccag
3661 tagaaaagtg tccactcagt ggggcctgct attcccctga gttcaaaggt caaatctgca
3721 gggtcaccac agtgacagag attggcaaag atgtgattgg tttaaggatc agtcctctgc
3781 agtttcgcta aggccccctt tgtgtgcatg ggtcagtcac catatgttcc ccccagagaa
3841 tgtgtctata tcctccttct aacagcacct tccccctgca gctactcttc agatctggct
3901 ctctgtaccc taaaacctag tatctttttc tcttctatgg aaaatccgaa ggtctaaact
3961 tgactttttt gaggtcttct caacttgact acagttgtgc tcataattgt ccttgccttt
4021 ccagcttaat tattttaagg aacaaatgaa aactctgggc tgggtggagt ggctcatacc
4081 tgtaatccca gcactttggg aggctacggt gggcagatca tctgaggcca ggagttcgag
4141 acctgcctgg ccaacatggc aacaccccgt ctctaataaa aatataaaaa ttagcctggc
4201 atggtagcat gcgcctatag tcccagctgc tcaggaggct gaggcatgag aatcgcttga
4261 acctaggagg tggaggttgc attcaactga gatcatacca cttcattcca gcctgggtga
4321 cagagcaaga ctctgtctca aaaaaaaaaa aaggaaaact ctgtgatgga catttgttta
4381 gtaaatccct tcagtattta tccctccttt ccccacagca gctttctttc ctgtcaacta
4441 gaaaggagca ggatgtaata aatacatttt ggtgtgacta ggccacacca actcttaatc
4501 atctcccatt ttccttagac atttaaattt caaggcaggt accctctgtg tactcagaaa
4561 tttgaagaag ttatttggtt ttccaaaatg cacactgcgg gttattgatt tgttctttac
4621 aactattgtt ctcatatttc tcacactaaa taaatctcta tgagagcttc aaaaaaaaaa
4681 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//