LOCUS BC038428 4250 bp mRNA linear HUM 24-MAR-2004
DEFINITION Homo sapiens dishevelled associated activator of morphogenesis 1,
mRNA (cDNA clone MGC:34720 IMAGE:4993504), complete cds.
ACCESSION BC038428
VERSION BC038428.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4250)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4250)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (01-OCT-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 52 Row: e Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21071076.
FEATURES Location/Qualifiers
source 1..4250
/db_xref="H-InvDB:HIT000259087"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:34720 IMAGE:4993504"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_10"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..4250
/gene="DAAM1"
/gene_synonym="KIAA0666"
/db_xref="GeneID:23002"
/db_xref="MIM:606626"
CDS 136..3342
/gene="DAAM1"
/gene_synonym="KIAA0666"
/codon_start=1
/product="DAAM1 protein"
/protein_id="AAH38428.1"
/db_xref="GeneID:23002"
/db_xref="MIM:606626"
/translation="MAPRKRGGRGISFIFCCFRNNDHPEITYRLRNDSNFALQTMEPA
LPMPPVEELDVMFSELVDELDLTDKHREAMFALPAEKKWQIYCSKKKDQEENKGATSW
PEFYIDQLNSMAARKSLLALEKEEEEERSKTIESLKTALRTKPMRFVTRFIDLDGLSC
ILNFLKTMDYETSESRIHTSLIGCIKALMNNSQGRAHVLAHSESINVIAQSLSTENIK
TKVAVLEILGAVCLVPGGHKKVLQAMLHYQKYASERTRFQTLINDLDKSTGRYRDEVS
LKTAIMSFINAVLSQGAGVESLDFRLHLRYEFLMLGIQPVIDKLREHENSTLDRHLDF
FEMLRNEDELEFAKRFELVHIDTKSATQMFELTRKRLTHSEAYPHFMSILHHCLQMPY
KRSGNTVQYWLLLDRIIQQIVIQNDKGQDPDSTPLENFNIKNVVRMLVNENEVKQWKE
QAEKMRKEHNELQQKLEKKERECDAKTQEKEEMMQTLNKMKEKLEKETTEHKQVKQQV
ADLTAQLHELSRRAVCASIPGGPSPGAPGGPFPSSVPGSLLPPPPPPPLPGGMLPPPP
PPLPPGGPPPPPGPPPLGAIMPPPGAPMGLALKKKSIPQPTNALKSFNWSKLPENKLE
GTVWTEIDDTKVFKILDLEDLERTFSAYQRQQKEADAIDDTLSSKLKVKELSVIDGRR
AQNCNILLSRLKLSNDEIKRAILTMDEQEDLPKDMLEQLLKFVPEKSDIDLLEEHKHE
LDRMAKADRFLFEMSRINHYQQRLQSLYFKKKFAERVAEVKPKVEAIRSGSEEVFRSG
ALKQLLEVVLAFGNYMNKGQRGNAYGFKISSLNKIADTKSSIDKNITLLHYLITIVEN
KYPSVLNLNEELRDIPQAAKVNMTELDKEISTLRSGLKAVETELEYQKSQPPQPGDKF
VSVVSQFITVASFSFSDVEDLLAEAKDLFTKAVKHFGEEAGKIQPDEFFGIFDQFLQA
VSEAKQENENMRKKKEEEERRARMEAQLKEQRERERKMRKAKENSEESGEFDDLVSAL
RSGEVFDKDLSKLKRNRKRITNQMTDSSRERPITKLNF"
misc_feature 268..834
/gene="DAAM1"
/gene_synonym="KIAA0666"
/note="Drf_GBD; Region: Diaphanous GTPase-binding Domain.
This domain is bound to by GTP-attached Rho proteins,
leading to activation of the Drf protein"
/db_xref="CDD:pfam06371"
misc_feature 838..1434
/gene="DAAM1"
/gene_synonym="KIAA0666"
/note="Drf_FH3; Region: Diaphanous FH3 Domain. This region
is found in the Formin-like and and diaphanous proteins"
/db_xref="CDD:pfam06367"
misc_feature 1933..3057
/gene="DAAM1"
/gene_synonym="KIAA0666"
/note="FH2; Region: Formin Homology 2 Domain"
/db_xref="CDD:pfam02181"
BASE COUNT 1407 a 857 c 931 g 1055 t
ORIGIN
1 cggacgcgtg ggcgagcggc tgtgaaggaa actgtttaac cggatcccat tgtacccaga
61 gtgcagagcc gcctttccag catgcagggg ctgctcagcg tttagtcaca tcaagaaata
121 gaacagaatt cagccatggc cccaagaaag agaggtggac gaggtatttc attcatcttt
181 tgctgtttcc gaaataatga tcacccagaa atcacgtatc ggctgcgaaa tgatagcaac
241 tttgcgcttc agaccatgga accagcattg cccatgcccc ctgtggagga gctggatgtc
301 atgttcagtg aactggtgga tgaactggac ctcacagaca aacacagaga agccatgttt
361 gcacttccag ctgagaaaaa atggcaaata tactgtagca agaaaaagga ccaggaagaa
421 aacaagggag ctacaagttg gcctgaattc tacattgatc agctcaattc catggctgct
481 agaaaatctc tgctggcttt agagaaggaa gaagaagaag aaagaagtaa aactatagag
541 agtttaaaga cagcactgag gacaaaacca atgaggtttg taaccagatt catcgacttg
601 gatggcctat catgtatcct caactttcta aagaccatgg actacgagac ctcagagtct
661 cgaatacata cttctctcat tggctgtata aaggcgttaa tgaacaactc tcaaggccgg
721 gctcacgtcc tggctcattc tgagagtatt aatgtaattg ctcagagtct gagcacagag
781 aacattaaaa cgaaggtggc cgtgctggaa atcttgggcg ccgtgtgcct ggttcccggg
841 ggccacaaga aggttctgca ggccatgctg cactaccaga agtatgccag cgaaaggacc
901 cgctttcaga cattaattaa cgacttggat aaaagcactg ggcggtatcg agatgaagtg
961 agtctcaaga ctgccatcat gtccttcatt aatgcagtgc tcagccaagg tgcaggagtg
1021 gagagtttgg actttagact tcatcttcgc tatgaatttc tgatgttagg aattcaacct
1081 gtaatagata aattaaggga acacgaaaat tcaacattag ataggcattt agactttttt
1141 gaaatgctcc gaaatgaaga tgaactagaa tttgccaaaa gatttgaact ggttcacata
1201 gacacaaaaa gtgcaactca gatgtttgag ctgaccagga agaggctgac acatagtgaa
1261 gcttacccgc atttcatgtc catcctgcac cactgcctcc aaatgcctta caagaggagt
1321 ggcaacactg ttcagtactg gctactacta gatagaatta tacagcagat agttatccag
1381 aatgacaaag gacaggaccc tgactccaca cctttggaaa actttaatat taagaatgtc
1441 gtacgaatgt tggttaatga aaatgaagtt aagcagtgga aagaacaagc ggaaaaaatg
1501 agaaaagagc acaatgagct acaacagaaa ctggaaaaga aagaacgaga atgtgatgct
1561 aagactcaag agaaggaaga gatgatgcag accttaaata aaatgaaaga gaaacttgaa
1621 aaggagacta ctgagcataa gcaagtcaag cagcaggtgg cggacctcac agcacagctc
1681 catgagctca gcaggagggc cgtctgtgct tcaatcccag gtggaccctc gcctggagca
1741 ccaggagggc cctttccttc ctctgtgcct ggatctctcc ttcctccccc accaccccca
1801 cctctaccag gtgggatgct tccccctcca ccgcctcccc tccctccagg tggccctcct
1861 cctcccccag ggcctcctcc cttaggggca atcatgccac ctcctggtgc tccaatgggc
1921 ctagcactga agaagaaaag cattcctcag cccacaaatg ccctgaaatc cttcaactgg
1981 tctaaactgc ccgagaacaa actggaagga acagtatgga ccgaaattga tgatacaaaa
2041 gtcttcaaaa ttctagatct tgaagacctg gaaagaacct tctctgccta tcaaagacag
2101 cagaaagaag cagatgccat tgatgacact ctgagttcca aacttaaagt taaagagctt
2161 tcggtgattg atggtcggag agctcagaat tgcaacatcc ttctatcgag gttgaaatta
2221 tccaatgacg aaatcaaacg ggcaattcta acaatggacg aacaggaaga tctgcccaag
2281 gacatgttgg aacagctctt gaaatttgtt cctgaaaaaa gtgacattga cctattggag
2341 gaacataaac acgaactgga tcggatggcc aaggctgata ggttcctttt tgagatgagc
2401 cgaattaatc actatcagca aaggttgcaa tcgctgtact tcaaaaagaa gtttgcagag
2461 cgtgtggcag aagtgaaacc taaagtggaa gcaattcgtt ctggctcaga agaggtgttt
2521 aggagtggtg ccctcaagca gttgctggag gtggttttgg catttggaaa ttatatgaat
2581 aaaggtcaaa gagggaatgc atatggattc aagatatcta gcctaaacaa aattgctgac
2641 acaaaatcca gcatcgacaa aaacattacc cttttgcact atctcatcac tattgtggaa
2701 aataagtacc ccagtgttct caatctaaat gaagaattgc gagatattcc tcaagctgcg
2761 aaagtaaaca tgactgagct ggacaaagaa ataagtacct tgagaagtgg cttgaaagca
2821 gtagagacag agctggaata tcagaagtct cagcccccac agcccggaga taagtttgtg
2881 tctgttgtca gccagttcat cacagtagcc agcttcagct tctctgatgt tgaagacctt
2941 ctagcagaag ctaaagacct gtttactaaa gcagtgaagc actttgggga agaggctggc
3001 aaaatacaac cagatgagtt ctttggcatt tttgatcaat ttcttcaagc tgtgtcagaa
3061 gccaaacaag aaaacgaaaa tatgagaaag aaaaaggagg aagaagaacg tcgagctcgc
3121 atggaagctc agctcaaaga acaacgtgaa agggaacgta aaatgagaaa agctaaagag
3181 aatagtgaag aaagcggaga gtttgatgac cttgtttcag ctttacgctc aggagaagtg
3241 tttgacaaag acctttctaa attgaaacgg aatcgcaaac gtattaccaa ccagatgact
3301 gacagcagca gagagagacc aatcacaaaa cttaatttct aattttccat gaatactttt
3361 ttttagaaag ctcattagca gccctctaaa gtgactagaa cgtttcatta cactgccttg
3421 caatccaaac agtggcaatt ttttccttca tctgtgagtg aatgtgtgaa cgtgtgtatg
3481 taaatgtatg tgtgtatata ttaaaaaatg tatatagatg tctgagtgtt gtctggagac
3541 ctatacgtat ggttaaaaag atttatgtta atgtatgtgc tccaaaacct ttcgtgtatg
3601 cattcacatt gagtgtggct cattttcttt ccccgaacgc catgactgtt cagaagcaca
3661 atactatctc ctgaaagaga taagagacat tccctagatt caaaggcaaa acagaagaaa
3721 caaacaaaca aacaaacaaa gcttgcaaaa tattttatgg tttccaagct tgatatcctt
3781 taaaattatt ttcattgatg gaactggagt tgttggaaaa acatagattt aaaatgattt
3841 ttgatagctg acattgtgat gttgatgtat cacatcagta ataggaccag ctttgaattt
3901 ctgacattgg tgtggggata cagtctgtaa atgtttattg agaacatctt gcacacaatt
3961 tgaattatgt agaatgtcaa tcaagttttt gtatatttaa aagttggaca tcaatttttt
4021 cccctgattt catcaagtta tctctgccaa gtgctcttga taatttcttc agatttttgg
4081 aaaaaaacac tatataaatg caatccatgc ttttttaaag aacaacattg ccagagtatg
4141 cttgttctaa caatatagat atataaacct taaaaataat aaaatatctc acccaagact
4201 taaaggaaga attctctgaa gggataaaga ttactaaaaa aaaaaaaaaa
//