LOCUS BC038294 3294 bp mRNA linear HUM 19-MAR-2009
DEFINITION Homo sapiens chromosome 10 open reading frame 46, mRNA (cDNA clone
MGC:33215 IMAGE:4837841), complete cds.
ACCESSION BC038294
VERSION BC038294.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3294)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3294)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-OCT-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 25, 2003 this sequence version replaced BC038294.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 47 Row: d Column: 1
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 54262140
The stop codon of the CDS annotated on this record is located > 55
bases upstream of a splice junction, and therefore the mRNA is
predicted to be subject to nonsense-mediated mRNA decay (NMD).
FEATURES Location/Qualifiers
source 1..3294
/db_xref="H-InvDB:HIT000052015"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:33215 IMAGE:4837841"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3294
/gene="C10orf46"
/db_xref="GeneID:143384"
/db_xref="HGNC:HGNC:23727"
CDS 485..1396
/gene="C10orf46"
/codon_start=1
/product="C10orf46 protein"
/protein_id="AAH38294.1"
/db_xref="GeneID:143384"
/db_xref="HGNC:HGNC:23727"
/translation="MEESMEEEEGGSYEAMMDDQNHNNWEAAVDGFRQPLPPPPPPSS
IPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANGVIMMLKSCDAAAAVAK
AAPAPTASSTININTSTSKFLMNVITIEDYKSTYWPKLDGAIDQLLTQSPGDYIPISY
EQIYSCVYKCVCQQHSEQMYSDLIKKITNHLERVSKELQASPPDLYIERFNIALGQYM
GALQSIVPLFIYMNKFYIETKLNRDLKDDLIKLFTEHVAEKHIYSLMPLLLEAQSTPF
QVTPSTMANIVKGLYTLRPVSQNFTAV"
BASE COUNT 914 a 759 c 785 g 836 t
ORIGIN
1 gaggccgggc agggggcggg gccggcgaat gcccgtcccg acccgtcgcg cctcccctgt
61 tagctccctg ccagccgagg cggggcgaac ctctgccctg ttgcgtggga gtgactcaca
121 gctcccgccc cttttggctc cgctttctcg cggccagtcc ctcgcaccac gtgccctcct
181 ggccgcgccc ccagctgccc tttccaactg cctgttggaa gccgctgtaa aacgtcgtga
241 ggagcgccgc tgctttacgg ctgcctctcc cagactagag ccccggagcg cccaccgccg
301 tcagccgcgt cttcaagcta gtcggccccg cggagagcga gagaccctgc gcaccgcagc
361 cctctccgct gcgcccattc ctgccgccgg cgatgtaact cggggaggca gcggtgcccg
421 ctggcccggg gttgagacag gcggcaggtg cctgtgaggc gggcgggtgc cgggggccag
481 caggatggag gaaagcatgg aagaggagga ggggggcagc tacgaggcga tgatggacga
541 ccagaaccac aacaactggg aggctgcggt ggacggcttc cggcagcccc tgccacctcc
601 gccgcccccc tcgtcgatcc cggcccctgc ccgagagcct ccgggggggc agctgctggc
661 ggtgcccgcg gtctccgtgg acaggaaagg ccccaaggag gggctcccga tggggccgca
721 gccaccgccg gaggctaatg gggtgatcat gatgttgaag agctgcgacg cggccgccgc
781 cgtggccaag gcggcccccg cccccaccgc cagctccacc atcaacatca acacctccac
841 ctccaagttc ttaatgaatg ttataactat tgaagattat aagagcacat actggccaaa
901 attggatggt gccatagatc aacttttaac tcagagtcct ggtgactata tccccatatc
961 ctatgaacag atatacagtt gtgtgtataa atgtgtatgc cagcagcact cggaacagat
1021 gtatagtgat ctgattaaaa agataactaa tcacttagag agagtctcaa aggagctgca
1081 ggccagccct ccagatctct atattgaaag atttaatata gctcttggac aatatatggg
1141 agcattgcag agcattgtgc ctcttttcat atatatgaat aagttttaca tcgaaaccaa
1201 gcttaacaga gacttaaaag atgaccttat aaagctgttt acggaacatg ttgcagaaaa
1261 gcacatttac agcctaatgc ctttactttt agaagcccag tcaacaccat ttcaggtcac
1321 accttcaact atggcaaata ttgtgaaagg cctgtatacc ctcagaccag tttctcagaa
1381 ttttacagca gtgtgatgaa gatggctcct gaaatagtag tgggttcaga tggctccaac
1441 tctattttct aaatttattc caaacattct ccctccggcg gtggaatctg aactttctga
1501 atatgctgct caagatcaga aatttcaaag agaacttata cagaatggtt ttacaagggg
1561 tgaccagtcc cggaagagag ctggggatga gttggcttat aatagctcgt cagcatgtgc
1621 aagttccagg gggtacagat agtgaatgta ttgaatatgc tttccttcct gaaaagagga
1681 cacactggag ctgcagagac tgtattcaga gcacagtggg ggctgcacac actcaggagc
1741 tctgtcacaa agctgttcat ggaagaggat gttggacttc ttacttggtt tgtaatttta
1801 aaacaaaaac taaaaaaaaa aaaaacgttg ctgctagact tgggggtgat tttgaaatgg
1861 gacaatcttt taatgagttt atctacagat tctgtgagga aaaagcatct cagaaagtga
1921 ccatttctaa gtgaaatctg acagccaaaa tcagcagctt cctccaaaaa tataagagca
1981 gaagaatttt ttttttaagc acttgttttg ttcatttgtg gacttggcat tttggtgtat
2041 tggtttcaca tgtcaggatc tcttttgctt taaaaccaag cagatcatta cagtacagta
2101 tttttcaccc acaaccaaaa caaccccttt taaaagagtt ggtctttgtt tagcattaga
2161 aagtcttgtt aaaggaaaat gctaactctg cttttgctag aactttcccc catcagttca
2221 caactttctt ctactctgtg ccttgagctt tgtgcacttt gcaactgtgt gaccatgttg
2281 tcaaactcct cctggagaag tgtatggtat ctaaactcac ccaccaagat ggcaggtgtg
2341 gccctgtagc aggatgctaa ttaagtggga aaatagaaac cttttgcaca tgggtcggat
2401 tttcccctgg ttcaccagag catattcata ttaatgttgg ggaccaactc tcctagagca
2461 tttccattcc ctgtgccact taacacgatg tctgtcacca gctgctatag tattggcagt
2521 actctagttt agggatgggc ggtactttag cacggaagct tcccttagta ttattgagag
2581 ctacttcctg cgatgctcta ggaagcagat acagttatta agtccaaata cacagtggtg
2641 tggggttcct gatcacttca ttttaaatga atgagataat tacttaaaaa aagtctgtca
2701 tttgaacatt atatttgagt gtgataggga agaagtagca ctgctgtcct aaggctccct
2761 tccagctgtg gcaaagctat atttctgttt ctccacatcc acagtgcttt ttagtccatc
2821 ataaaagttt ctgaagctta ttctagctgt tgttgaaagc ccaagaaaaa tagatgtggc
2881 aagagaaaaa tacttttctt ctcaattttg cttgaatctt aattgagcat aggcttctct
2941 actaggcaac atcagactaa tagtatttac ctcttcagag aacttgaggg gaaaagaaac
3001 atcccaggga tgctgtcgca tgtctgctct gcaggttctt catacagctg cctctgccaa
3061 ttcagtttat tttttggggg gagtggtgtg ggtgggagag ttagaagtgg gatattggga
3121 gcaagtaagt cacccaataa ttgaagtcct tgatttgtaa aactgttata cagagaagta
3181 aagataaagg ttgtcagatt tattttttaa agtaaaaaaa aaaaaaaaaa aaaaaaaaaa
3241 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa aaaaaaaaaa aaaa
//