LOCUS BC038239 3960 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens tyrosine kinase with immunoglobulin-like and EGF-like
domains 1, mRNA (cDNA clone MGC:46155 IMAGE:5767075), complete cds.
ACCESSION BC038239
VERSION BC038239.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3960)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3960)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (30-SEP-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 79 Row: p Column: 16
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 31543809.
FEATURES Location/Qualifiers
source 1..3960
/db_xref="H-InvDB:HIT000052011"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:46155 IMAGE:5767075"
/tissue_type="Lung, Spleen, fetal, pooled"
/clone_lib="NIH_MGC_122"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3960
/gene="TIE1"
/gene_synonym="JTK14"
/db_xref="GeneID:7075"
/db_xref="HGNC:HGNC:11809"
/db_xref="MIM:600222"
CDS 80..3496
/gene="TIE1"
/gene_synonym="JTK14"
/codon_start=1
/product="tyrosine kinase with immunoglobulin-like and
EGF-like domains 1"
/protein_id="AAH38239.1"
/db_xref="GeneID:7075"
/db_xref="HGNC:HGNC:11809"
/db_xref="MIM:600222"
/translation="MVWRVPPFLLPILFLASHVGAAVDLTLLANLRLTDPQRFFLTCV
SGEAGAGRGSDAWGPPLLLEKDDRIVRTPPGPPLRLARNGSHQVTLRGFSKPSDLVGV
FSCVGGAGARRTRVIYVHNSPGAHLLPDKVTHTVNKGDTAVLSARVHKEKQTDVIWKS
NGSYFYTLDWHEAQDGRFLLQLPNVQPPSSGIYSATYLEASPLGSAFFRLIVRGCGAG
RWGPGCTKECPGCLHGGVCHDHDGECVCPPGFTGTRCEQACREGRFGQSCQEQCPGIS
GCRGLTFCLPDPYGCSCGSGWRGSQCQEACAPGHFGADCRLQCQCQNGGTCDRFSGCV
CPSGWHGVHCEKSDRIPQILNMASELEFNLETMPRINCAAAGNPFPVRGSIELRKPDG
TVLLSTKAIVEPEKTTAEFEVPRLVLADSGFWECRVSTSGGQDSRRFKVNVKVPPVPL
AAPRLLTKQSRQLVVSPLVSFSGDGPISTVRLHYRPQDSTMDWSTIVVDPSENVTLMN
LRPKTGYSVRVQLSRPGEGGEGAWGPPTLMTTDCPEPLLQPWLEGWHVEGTDRLRVSW
SLPLVPGPLVGDGFLLRLWDGTRGQERRENVSSPQARTALLTGLTPGTHYQLDVQLYH
CTLLGPASPPAHVLLPPSGPPAPRHLHAQALSDSEIQLTWKHPEALPGPISKYVVEVQ
VAGGAGDPLWIDVDRPEETSTIIRGLNASTRYLFRMRASIQGLGDWSNTVEESTLGNG
LQAEGPVQESRAAEEGLDQQLILAVVGSVSATCLTILAALLTLVCIRRSCLHRRRTFT
YQSGSGEETILQFSSGTLTLTRRPKLQPEPLSYPVLEWEDITFEDLIGEGNFGQVIRA
MIKKDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLGACKNRGYLY
IAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDAANGMQYLSE
KQFIHRDLAARNVLVGENLASKIADFGLSRGEEVYVKKTMGRLPVRWMAIESLNYSVY
TTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNCDDEVYELMRQ
CWRDRPYERPPFAQIALQLGRMLEARKAYVNMSLFENFTYAGIDATAEEA"
BASE COUNT 826 a 1196 c 1166 g 772 t
ORIGIN
1 cacaggctga gcagtcaggc ccacagcatc tgaccccagg cccagctcgt cctggctggc
61 ctgggtcggc ctctggagta tggtctggcg ggtgccccct ttcttgctcc ccatcctctt
121 cttggcttct catgtgggcg cggcggtgga cctgacgctg ctggccaacc tgcggctcac
181 ggacccccag cgcttcttcc tgacttgcgt gtctggggag gccggggcgg ggaggggctc
241 ggacgcctgg ggcccgcccc tgctgctgga gaaggacgac cgtatcgtgc gcaccccgcc
301 cgggccaccc ctgcgcctgg cgcgcaacgg ttcgcaccag gtcacgcttc gcggcttctc
361 caagccctcg gacctcgtgg gcgtcttctc ctgcgtgggc ggtgctgggg cgcggcgcac
421 gcgcgtcatc tacgtgcaca acagccctgg agcccacctg cttccagaca aggtcacaca
481 cactgtgaac aaaggtgaca ccgctgtact ttctgcacgt gtgcacaagg agaagcagac
541 agacgtgatc tggaagagca acggatccta cttctacacc ctggactggc atgaagccca
601 ggatgggcgg ttcctgctgc agctcccaaa tgtgcagcca ccatcgagcg gcatctacag
661 tgccacttac ctggaagcca gccccctggg cagcgccttc tttcggctca tcgtgcgggg
721 ttgtggggct gggcgctggg ggccaggctg taccaaggag tgcccaggtt gcctacatgg
781 aggtgtctgc cacgaccatg acggcgaatg tgtatgcccc cctggcttca ctggcacccg
841 ctgtgaacag gcctgcagag agggccgttt tgggcagagc tgccaggagc agtgcccagg
901 catatcaggc tgccggggcc tcaccttctg cctcccagac ccctatggct gctcttgtgg
961 atctggctgg agaggaagcc agtgccaaga agcttgtgcc cctggtcatt ttggggctga
1021 ttgccgactc cagtgccagt gtcagaatgg tggcacttgt gaccggttca gtggttgtgt
1081 ctgcccctct gggtggcatg gagtgcactg tgagaagtca gaccggatcc cccagatcct
1141 caacatggcc tcagaactgg agttcaactt agagacgatg ccccggatca actgtgcagc
1201 tgcagggaac cccttccccg tgcggggcag catagagcta cgcaagccag acggcactgt
1261 gctcctgtcc accaaggcca ttgtggagcc agagaagacc acagctgagt tcgaggtgcc
1321 ccgcttggtt cttgcggaca gtgggttctg ggagtgccgt gtgtccacat ctggcggcca
1381 agacagccgg cgcttcaagg tcaatgtgaa agtgcccccc gtgcccctgg ctgcacctcg
1441 gctcctgacc aagcagagcc gccagcttgt ggtctccccg ctggtctcgt tctctgggga
1501 tggacccatc tccactgtcc gcctgcacta ccggccccag gacagtacca tggactggtc
1561 gaccattgtg gtggacccca gtgagaacgt gacgttaatg aacctgaggc caaagacagg
1621 atacagtgtt cgtgtgcagc tgagccggcc aggggaagga ggagaggggg cctgggggcc
1681 tcccaccctc atgaccacag actgtcctga gcctttgttg cagccgtggt tggagggctg
1741 gcatgtggaa ggcactgacc ggctgcgagt gagctggtcc ttgcccttgg tgcccgggcc
1801 actggtgggc gacggtttcc tgctgcgcct gtgggacggg acacgggggc aggagcggcg
1861 ggagaacgtc tcatcccccc aggcccgcac tgccctcctg acgggactca cgcctggcac
1921 ccactaccag ctggatgtgc agctctacca ctgcaccctc ctgggcccgg cctcgccccc
1981 tgcacacgtg cttctgcccc ccagtgggcc tccagccccc cgacacctcc acgcccaggc
2041 cctctcagac tccgagatcc agctgacatg gaagcacccg gaggctctgc ctgggccaat
2101 atccaagtac gttgtggagg tgcaggtggc tgggggtgca ggagacccac tgtggataga
2161 cgtggacagg cctgaggaga caagcaccat catccgtggc ctcaacgcca gcacgcgcta
2221 cctcttccgc atgcgggcca gcattcaggg gctcggggac tggagcaaca cagtagaaga
2281 gtccaccctg ggcaacgggc tgcaggctga gggcccagtc caagagagcc gggcagctga
2341 agagggcctg gatcagcagc tgatcctggc ggtggtgggc tccgtgtctg ccacctgcct
2401 caccatcctg gccgcccttt taaccctggt gtgcatccgc agaagctgcc tgcatcggag
2461 acgcaccttc acctaccagt caggctcggg cgaggagacc atcctgcagt tcagctcagg
2521 gaccttgaca cttacccggc ggccaaaact gcagcccgag cccctgagct acccagtgct
2581 agagtgggag gacatcacct ttgaggacct catcggggag gggaacttcg gccaggtcat
2641 ccgggccatg atcaagaagg acgggctgaa gatgaacgca gccatcaaaa tgctgaaaga
2701 gtatgcctct gaaaatgacc atcgtgactt tgcgggagaa ctggaagttc tgtgcaaatt
2761 ggggcatcac cccaacatca tcaacctcct gggggcctgt aagaaccgag gttacttgta
2821 tatcgctatt gaatatgccc cctacgggaa cctgctagat tttctgcgga aaagccgggt
2881 cctagagact gacccagctt ttgctcgaga gcatgggaca gcctctaccc ttagctcccg
2941 gcagctgctg cgtttcgcca gtgatgcggc caatggcatg cagtacctga gtgagaagca
3001 gttcatccac agggacctgg ctgcccggaa tgtgctggtc ggagagaacc tagcctccaa
3061 gattgcagac ttcggccttt ctcggggaga ggaggtttat gtgaagaaga cgatggggcg
3121 tctccctgtg cgctggatgg ccattgagtc cctgaactac agtgtctata ccaccaagag
3181 tgatgtctgg tcctttggag tccttctttg ggagatagtg agccttggag gtacacccta
3241 ctgtggcatg acctgtgccg agctctatga aaagctgccc cagggctacc gcatggagca
3301 gcctcgaaac tgtgacgatg aagtgtacga gctgatgcgt cagtgctggc gggaccgtcc
3361 ctatgagcga cccccctttg cccagattgc gctacagcta ggccgcatgc tggaagccag
3421 gaaggcctat gtgaacatgt cgctgtttga gaacttcact tacgcgggca ttgatgccac
3481 agctgaggag gcctgagctg ccatccagcc agaacgtggc tctgctggcc ggagcaaact
3541 ctgctgtcta acctgtgacc agtctgaccc ttacagcctc tgacttaagc tgcctcaagg
3601 aattttttta acttaaggga gaaaaaaagg gatctgggga tggggtgggc ttaggggaac
3661 tgggttccca tgctttgtag gtgtctcata gctatcctgg gcatccttct ttctagttca
3721 gctgccccac aggtgtgttt cccatcccac tgctccccca acacaaaccc ccactccagc
3781 tccttcgctt aagccagcac tcacaccact aacatgccct gttcagctac tcccactccc
3841 ggcctgtcat tcagaaaaaa ataaatgttc taataagctc caaaaaaaaa aaaaaaaaaa
3901 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//