LOCUS BC038184 1050 bp mRNA linear HUM 15-FEB-2005
DEFINITION Homo sapiens HECT, UBA and WWE domain containing 1, mRNA (cDNA
clone IMAGE:4577920), partial cds.
ACCESSION BC038184
VERSION BC038184.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1050)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1050)
AUTHORS Director MGC Project.
TITLE Direct Submission
JOURNAL Submitted (24-SEP-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steve Jones, Sarah Barber, Mabel Brown-John, Yaron Butterfield,
Andy Chan, Steve S. Chand, William Chow, Alison Cloutier, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Amara Masson, Mike R. Mayo, Josh Moran, Ryan Morin,
Teika Olson, Diana Palmquist, Anca Petrescu, Anna Liisa Prahbu,
Parvaneh Saeedi, JR Santos, Angelique Schnerch, Ursula Skalska,
Duane Smailus, Jeff Stott, Miranda Tsai, George Yang, Jacquie
Schein, Asim Siddiqui, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 43 Row: e Column: 24
This clone was selected for full length sequencing because it
passed the following selection criteria: Similarity but not
identity to protein.
FEATURES Location/Qualifiers
source 1..1050
/db_xref="H-InvDB:HIT000095107"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4577920"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_20"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..>1050
/gene="HUWE1"
/gene_synonym="5430439H10Rik"
/gene_synonym="dJ339A18.2"
/gene_synonym="FLJ20030"
/gene_synonym="HSPC272"
/gene_synonym="Ib772"
/gene_synonym="UREB1"
/db_xref="GeneID:10075"
CDS 403..>1050
/gene="HUWE1"
/gene_synonym="5430439H10Rik"
/gene_synonym="dJ339A18.2"
/gene_synonym="FLJ20030"
/gene_synonym="HSPC272"
/gene_synonym="Ib772"
/gene_synonym="UREB1"
/codon_start=1
/product="HUWE1 protein"
/protein_id="AAH38184.1"
/db_xref="GeneID:10075"
/translation="MKVDRTKLKKTPTEAPADCRALIDKLKVCNDEQLLLELQQIKTW
NIGKCELYHWVDLLDRFDGILADAGQTVENMSWMLVCDRPEREQLKMLLLAVLNFTAL
LIEYSFSRHLYSSIEHLTTLLASSDMQVVLAVLNLLYVFSKRSNYITRLGSDKRTPLL
TRLQHLAESWGGKENGFGLAECCRDLHMMKYPPSATTLHFEFYADPGAEVKKKKKK"
BASE COUNT 282 a 232 c 315 g 221 t
ORIGIN
1 gaggctttcg actgagggct agcgagggga gcagggctgg agcagggctg gagcagggct
61 ggagcagggc tggagcaggg ctgaagcagg gccgcggacc ccgcacgctc ctgcgggccc
121 cgcggagcca ttgcggccga ggcctcggca ggcgccagcg gagagctagc cgcatcttcg
181 ggggcagccc ggcagctgcc ggcggcgcgg cgagagagcg gctgacagag gggatgcgag
241 gtcctccagc agcctgacct gagtgggtta gtgatccaga gaaaccagca ggccaacttg
301 gtcaggaagg ttcgggaagc tgttggagca gtgtggggaa tttcccacca ggatgagtat
361 gattggctgt gattttagat cgtaaagctg aaaattgaaa tcatgaaagt agacaggact
421 aaactgaaga agacacctac tgaggctcct gcagactgca gagccttaat agacaaactc
481 aaagtttgta atgatgagca acttctcttg gaactgcagc agatcaaaac atggaacatt
541 ggaaagtgcg agttatatca ctgggtggac ctgttggacc gcttcgatgg aatactggca
601 gatgctggac agacagtgga gaatatgtca tggatgctcg tatgtgatag gccagaaaga
661 gagcaactga aaatgcttct cttggctgtg ttgaacttca cagccttgct cattgagtac
721 agcttttccc ggcatctgta cagttccata gagcatttga caactttatt ggcttcctct
781 gatatgcaag tggtgctggc agtcctcaat ctcctatatg tatttagcaa aagatcaaac
841 tacatcactc gtctgggatc tgacaagagg accccgctgc taactcggct acaacatttg
901 gcagagagct ggggtggaaa ggagaatggc tttggacttg cagaatgttg cagagacttg
961 catatgatga aatatccacc cagtgcaact acactacact ttgaattcta tgcagatcct
1021 ggggccgagg tcaaaaaaaa aaaaaaaaaa
//