LOCUS BC036866 1756 bp mRNA linear HUM 24-JAN-2005
DEFINITION Homo sapiens mutL homolog 3 (E. coli), mRNA (cDNA clone
IMAGE:5198926), partial cds.
ACCESSION BC036866
VERSION BC036866.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1756)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1756)
AUTHORS Director MGC Project.
TITLE Direct Submission
JOURNAL Submitted (23-AUG-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Sep 16, 2003 this sequence version replaced BC036866.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 78 Row: f Column: 17.
FEATURES Location/Qualifiers
source 1..1756
/db_xref="H-InvDB:HIT000094668"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:5198926"
/tissue_type="Brain, adult, 6 pooled whole brains"
/clone_lib="NIH_MGC_114"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..1756
/gene="MLH3"
/gene_synonym="HNPCC"
/gene_synonym="S240II117"
/db_xref="GeneID:27030"
/db_xref="MIM:604395"
CDS <1..1010
/gene="MLH3"
/gene_synonym="HNPCC"
/gene_synonym="S240II117"
/codon_start=3
/product="MLH3 protein"
/protein_id="AAH36866.1"
/db_xref="GeneID:27030"
/db_xref="MIM:604395"
/translation="SQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESL
QSLFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVD
NKFIACLMSTKTEENGEADSYEKQQAQGSGRKKLLSSTLIPPLEITVTEEQRRLLWCY
HKNLEDLGLEFVFPDTSDSLVLVGKVPLCFVEREANELRRGRSTVTKSIVEEFIREQL
ELLQTTGGIQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRLIEALSSCQLPFQCA
HGRPSMLPLADIDHLEQEKQIKPNLTKLRKMAQAWRLFGKAECDTRQSLQQSMPPCEP
P"
BASE COUNT 501 a 376 c 394 g 485 t
ORIGIN
1 ggtctcagta caggtgtcaa ccttttagaa gcgaccttgt tcttcctttc cttccgagag
61 ctcgagcaga gaggactgtg atgagacagg ataacagaga tactgtggat gatactgtta
121 gtagcgaatc gcttcagtct ttgttctcag aatgggacaa tccagtattt gcccgttatc
181 cagaggttgc tgttgatgta agcagtggcc aggctgagag cttagcagtt aaaattcaca
241 acatcttgta tccctatcgt ttcaccaaag gaatgattca ttcaatgcag gttctccagc
301 aagtagataa caagtttatt gcctgtttga tgagcactaa gactgaagag aatggcgagg
361 cagattccta cgagaagcaa caggcacaag gctctggtcg gaaaaaatta ctgtcttcta
421 ctctaattcc tccgctagag ataacagtga cagaggaaca aaggagactc ttatggtgtt
481 accacaaaaa tctggaagat ctgggccttg aatttgtatt tccagacact agtgattctc
541 tggtccttgt gggaaaagta ccactatgtt ttgtggaaag agaagccaat gaacttcgga
601 gaggaagatc tactgtgacc aagagtattg tggaggaatt tatccgagaa caactggagc
661 tactccagac caccggaggc atccaaggga cattgccact gactgtccag aaggtgttgg
721 catcccaagc ctgccatggg gccattaagt ttaatgatgg cctgagctta caggaaagtt
781 gccgccttat tgaagctctg tcctcatgcc agctgccatt ccagtgtgct cacgggagac
841 cttctatgct gccgttagct gacatagacc acttggaaca ggaaaaacag attaaaccca
901 acctcactaa acttcgcaaa atggcccagg cctggcgtct ctttggaaaa gcagagtgtg
961 atacaaggca gagcctgcag cagtccatgc ctccctgtga gccaccatga gaacagaatc
1021 actggtctaa aaggaacaaa gggatgttca ctgtatgcct ctgagcagag agcagcagca
1081 gcaggtacca gcacggccct gactgaatca gcccagtgtc cctgagcagc ttagacagca
1141 gggctctctg tatcagtctt tcttgagcag atgattcccc tagttgagta gccagatgaa
1201 attcaagcct aaagacaatt cattcatttg catccatggg cacagaaggt tgctatatag
1261 tatctacctt ttgctactta tttaatgata aaatttaatg acagtttgat tggttgcttg
1321 gtttgttatt tgaagggtgt gatttttgtt tttgtacagt tttttttcaa gcttcacatt
1381 tgcgtgtatc taattcagct gatgctcaag tccaaggggt agtctgcctt cccaggctgc
1441 ccccagggtt tctgcactgg tcccctcttt tcccttcagt cttcttcact tccctatgct
1501 gctgcttcat gtgctacatc tcagacttaa agagtttctc tactacagtg aaaacattct
1561 ctagggtctt tcatcaggcc tttagttatt ttagggataa aaactattga taaaaaggac
1621 aaggatagaa cagagaaaat ttaaagtcct gttccgggtt ttttgttatg ttttctttaa
1681 aaactcagag actgatgttc aatatcccaa accagtaaaa tggtgaaaat acaaaaaaaa
1741 aaaaaaaaaa aaaaaa
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