LOCUS BC036703 3233 bp mRNA linear HUM 11-AUG-2006
DEFINITION Homo sapiens karyopherin (importin) beta 1, mRNA (cDNA clone
MGC:2155 IMAGE:3162957), complete cds.
ACCESSION BC036703
VERSION BC036703.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3233)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3233)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (23-AUG-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC036703.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 5 Row: c Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 24797084.
FEATURES Location/Qualifiers
source 1..3233
/db_xref="H-InvDB:HIT000051773"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:2155 IMAGE:3162957"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3233
/gene="KPNB1"
/gene_synonym="IMB1"
/gene_synonym="Impnb"
/gene_synonym="IPOB"
/gene_synonym="MGC2155"
/gene_synonym="MGC2156"
/gene_synonym="MGC2157"
/gene_synonym="NTF97"
/db_xref="GeneID:3837"
/db_xref="HGNC:HGNC:6400"
/db_xref="MIM:602738"
CDS 308..2938
/gene="KPNB1"
/gene_synonym="IMB1"
/gene_synonym="Impnb"
/gene_synonym="IPOB"
/gene_synonym="MGC2155"
/gene_synonym="MGC2156"
/gene_synonym="MGC2157"
/gene_synonym="NTF97"
/codon_start=1
/product="karyopherin (importin) beta 1"
/protein_id="AAH36703.1"
/db_xref="GeneID:3837"
/db_xref="HGNC:HGNC:6400"
/db_xref="MIM:602738"
/translation="MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVL
ANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTE
TYRPSSASQCVAGIACAEIPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQD
IDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFI
MQVVCEATQCPDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVA
LQGIEFWSNVCDEEMDLAIEASEAAEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQD
ENDDDDDWNPCKAAGVCLMLLATCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGC
ILEGPEPSQLKPLVIQAMPTLIELMKDPSVVVRDTAAWTVGRICELLPEAAINDVYLA
PLLQCLIEGLSAEPRVASNVCWAFSSLAEAAYEAADVADDQEEPATYCLSSSFELIVQ
KLLETTDRPDGHQNNLRSSAYESLMEIVKNSAKDCYPAVQKTTLVIMERLQQVLQMES
HIQSTSDRIQFNDLQSLLCATLQNVLRKVQHQDALQISDVVMASLLRMFQSTAGSGGV
QEDALMAVSTLVEVLGGEFLKYMEAFKPFLGIGLKNYAEYQVCLAAVGLVGDLCRALQ
SNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDIALAIGGEFKKYLEVVLNTLQ
QASQAQVDKSDYDMVDYLNELRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFIL
SFIDHIAGDEDHTDGVVACAAGLIGDLCTAFGKDVLKLVEARPMIHELLTEGRRSKTN
KAKTLATWATKELRKLKNQA"
BASE COUNT 903 a 753 c 823 g 754 t
ORIGIN
1 ctcactcaca gcctcccttc cttctttctc cctccgcctc ccgagcacca gcgcgctctg
61 agctgccccc agggtccctc ccccgccgcc agcagcccat ttggagggag gaagtaaggg
121 aagaggagag gaaggggagc cggaccgact acccagacag agccggtgaa tgggtttgtg
181 gtgacccccg ccccccaccc caccctccct tcccacccga cccccaaccc ccatccccag
241 ttcgagccgc cgcccgaaag gccgggccgt cgtcttagga ggagtcgccg ccgccgccac
301 ctccgccatg gagctgatca ccattctcga gaagaccgtg tctcccgatc ggctggagct
361 ggaagcggcg cagaagttcc tggagcgtgc ggccgtggag aacctgccca ctttccttgt
421 ggaactgtcc agagtgctgg caaatccagg aaacagtcag gttgccagag ttgcagctgg
481 tctacaaatc aagaactctt tgacatctaa agatccagat atcaaggcac aatatcagca
541 gaggtggctt gctattgatg ctaatgctcg acgagaagtc aagaactatg ttttgcagac
601 attgggtaca gaaacttacc ggcctagttc tgcctcacag tgtgtggctg gtattgcttg
661 tgcagagatc ccagtaaacc agtggccaga actcattcct cagctggtgg ccaatgtcac
721 aaaccccaac agcacagagc acatgaagga gtcgacattg gaagccatcg gttatatttg
781 ccaagatata gacccagagc agctacaaga taaatccaat gagattctga ctgccataat
841 ccaggggatg aggaaagaag agcctagtaa taatgtgaag ctagctgcta cgaatgcact
901 cctgaactca ttggagttca ccaaagcaaa ctttgataaa gagtctgaaa ggcactttat
961 tatgcaggtg gtctgtgaag ccacacagtg tccagatacg agggtacgag tggctgcttt
1021 acagaatctg gtgaagataa tgtccttata ttatcagtac atggagacat atatgggtcc
1081 tgctcttttt gcaatcacaa tcgaagcaat gaaaagtgac attgatgagg tggctttaca
1141 agggatagaa ttctggtcca atgtctgtga tgaggaaatg gatttggcca ttgaagcttc
1201 agaggcagca gaacaaggac ggccccctga gcacaccagc aagttttatg cgaagggagc
1261 actacagtat ctggttccaa tcctcacaca gacactaact aaacaggacg aaaatgatga
1321 tgacgatgac tggaacccct gcaaagcagc aggggtgtgc ctcatgcttc tggccacctg
1381 ctgtgaagat gacattgtcc cacatgtcct ccccttcatt aaagaacaca tcaagaaccc
1441 agattggcgg taccgggatg cagcagtgat ggcttttggt tgtatcttgg aaggaccaga
1501 gcccagtcag ctcaaaccac tagttataca ggctatgccc accctaatag aattaatgaa
1561 agaccccagt gtagttgttc gagatacagc tgcatggact gtaggcagaa tttgtgagct
1621 gcttcctgaa gctgccatca atgatgtcta cttggctccc ctgctacagt gtctgattga
1681 gggtctcagt gctgaaccca gagtggcttc aaatgtgtgc tgggctttct ccagtctggc
1741 tgaagctgct tatgaagctg cagacgttgc tgatgatcag gaagaaccag ctacttactg
1801 cttatcttct tcatttgaac tcatagttca gaagctccta gagactacag acagacctga
1861 tggacaccag aacaacctga ggagttctgc atatgaatct ctgatggaaa ttgtgaaaaa
1921 cagtgccaag gattgttatc ctgctgtcca gaaaacgact ttggtcatca tggaacgact
1981 gcaacaggtt cttcagatgg agtcacatat ccagagcaca tccgatagaa tccagttcaa
2041 tgaccttcag tctttactct gtgcaactct tcagaatgtt cttcggaaag tgcaacatca
2101 agatgctttg cagatctctg atgtggttat ggcctccctg ttaaggatgt tccaaagcac
2161 agctgggtct gggggagtac aagaggatgc cctgatggca gttagcacac tggtggaagt
2221 gttgggtggt gaattcctca agtacatgga ggcctttaaa cccttcctgg gcattggatt
2281 aaaaaattat gctgaatacc aggtttgttt ggcagctgtg ggcttagtgg gagacttgtg
2341 ccgtgccctg caatccaaca tcataccttt ctgtgacgag gtgatgcagc tgcttctgga
2401 aaatttgggg aatgagaacg tccacaggtc tgtgaagccg cagattctgt cagtgtttgg
2461 tgatattgcc cttgctattg gaggagagtt taaaaaatac ttagaggttg tattgaatac
2521 tcttcagcag gcctcccaag cccaggtgga caagtcagac tatgacatgg tggattatct
2581 gaatgagcta agggaaagct gcttggaagc ctatactgga atcgtccagg gattaaaggg
2641 ggatcaggag aacgtacacc cggatgtgat gctggtacaa cccagagtag aatttattct
2701 gtctttcatt gaccacattg ctggagatga ggatcacaca gatggagtag tagcttgtgc
2761 tgctggacta ataggggact tatgtacagc atttgggaag gatgtactga aattagtaga
2821 agctaggcca atgatccatg aattgttaac tgaagggcgg agatcgaaga ctaacaaagc
2881 aaaaaccctt gctacatggg caacaaaaga actgaggaaa ctgaagaacc aagcttgatc
2941 tgttaccatt gggatgataa cctgaggacc cccactggaa atctcccatc ttttgaaaaa
3001 cctggaagtg aggagtgtgc acggatgctg aatgtttggg aatgagagga tgagtgagtg
3061 aggcttgaaa acacaccaca ttgaaaatcc tgccacagca gcagccgcag ccgccaacag
3121 cagcgctgtt agtgagctaa gtaagcactg acttcgtaga aaaccataac atcggccatc
3181 ttggaaaaga gaaaaacaat ggagttactt atttaaaaaa aaaaaaaaaa aaa
//