LOCUS BC036651 4730 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens PTK2B protein tyrosine kinase 2 beta, mRNA (cDNA clone
MGC:26516 IMAGE:4824966), complete cds.
ACCESSION BC036651
VERSION BC036651.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4730)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4730)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (23-AUG-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Sep 16, 2003 this sequence version replaced BC036651.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 33 Row: k Column: 1
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 27886585.
FEATURES Location/Qualifiers
source 1..4730
/db_xref="H-InvDB:HIT000094547"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:26516 IMAGE:4824966"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..4730
/gene="PTK2B"
/gene_synonym="CADTK"
/gene_synonym="CAKB"
/gene_synonym="FADK2"
/gene_synonym="PKB"
/gene_synonym="PTK"
/gene_synonym="PYK2"
/gene_synonym="RAFTK"
/db_xref="GeneID:2185"
/db_xref="HGNC:HGNC:9612"
/db_xref="MIM:601212"
CDS 809..3838
/gene="PTK2B"
/gene_synonym="CADTK"
/gene_synonym="CAKB"
/gene_synonym="FADK2"
/gene_synonym="PKB"
/gene_synonym="PTK"
/gene_synonym="PYK2"
/gene_synonym="RAFTK"
/codon_start=1
/product="PTK2B protein tyrosine kinase 2 beta"
/protein_id="AAH36651.1"
/db_xref="GeneID:2185"
/db_xref="HGNC:HGNC:9612"
/db_xref="MIM:601212"
/translation="MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVC
FYSNSFNPGKNFKLVKCTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEI
HWLHPQMTVGEVQDKYECLHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRN
DYMQRYASKVSEGMALQLGCLELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQM
QENLKPKQFRKMIQQTFQQYASLREEECVMKFFNTLAGFANIDQETYRCELIQGWNIT
VDLVIGPKGIRQLTSQDAKPTCLAEFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIK
TSSLAEAENMADLIDGYCRLQGEHQGSLIIHPRKDGEKRNSLPQIPMLNLEARRSHLS
ESCSIESDIYAEIPDETLRRPGGPQYGIAREDVVLNRILGEGFFGEVYEGVYTNHKGE
KINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYG
ELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLG
DFGLSRYIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQ
PFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDV
YQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRPKYRPPPQTNLLAPKLQFQVP
EGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMREEDFIQPSSREEAQQLWE
AEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSPLTPEKEVGYLEFTGPP
QKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQLPPEGYVVVVKNVG
LTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLAQQNAVTSLSEEC
KRQMLTASHTLAMDAKNLLDAVDQAKVLANLAHPPAE"
BASE COUNT 1098 a 1320 c 1309 g 1003 t
ORIGIN
1 gcagttcccg cctcctcagg tccgggcggg tccctggccg gggtagcacg gaagggtctc
61 ccaggcggcg tagtagggct tccgtgttac tggaaaccta cttccggctg caaatgggaa
121 aaggagcctc ttccttaacc aatccccggg aacctcaggc ccgcggatgg gagaaaccag
181 agatgccaac ttcctgcttc cgaagtagtg gctgggtctt aaagcaccga tgtttctgca
241 ttgaatagcc ctggaagaca gaattcttgt ctctccaaag atctggcaga cttattccca
301 attataagag atccttgcaa aggaggtgtc ttgcttcacc ttcaccttcc actgtgattg
361 taagttttct gaggcctcgc cagccatgcg gaactgaata ggactagcaa cttcatagac
421 ggttgtgaag acaagctaga cggcagatga aagttcttgg cacagagtga acacttgata
481 aactatatgg cagggagggc tggaacgggg cttgtttgaa gagcaatatg agccagggtt
541 atagacctga gtttggggta agagtggaac atccaaatgg aagagtccag cagctgaaag
601 gacatttgtt caaaggcctt tttcattaca gttttctcct tcttctgatc cagccacagc
661 ctccggagcc gttgcacacc tacctgcccg gccgacttac ctgtacttgc cgccgtcccg
721 gctcacctgg cggtgcccga ggagtagtcg ctggagtccg cgcctccctg ggactgcaat
781 gtgccgatct tagctgctgc ctgagaggat gtctggggtg tccgagcccc tgagtcgagt
841 aaagttgggc acgttacgcc ggcctgaagg ccctgcagag cccatggtgg tggtaccagt
901 agatgtggaa aaggaggacg tgcgtatcct caaggtctgc ttctatagca acagcttcaa
961 tcctgggaaa aacttcaaac tggtcaaatg cactgtccag acggagatcc gggagatcat
1021 cacctccatc ctgctgagcg ggcggatcgg gcccaacatc cggttggctg agtgctatgg
1081 gctgaggctg aagcacatga agtccgatga gatccactgg ctgcacccac agatgacagt
1141 gggtgaggtg caggacaagt atgagtgtct gcacgtggaa gccgagtgga ggtatgacct
1201 tcaaatccgc tacttgccag aagacttcat ggagagcctg aaggaggaca ggaccacgct
1261 gctctatttt taccaacagc tccggaacga ctacatgcag cgctacgcca gcaaggtcag
1321 cgagggcatg gccctgcagc tgggctgcct ggagctcagg cggttcttca aggatatgcc
1381 ccacaatgca cttgacaaga agtccaactt cgagctccta gaaaaggaag tggggctgga
1441 cttgtttttc ccaaagcaga tgcaggagaa cttaaagccc aaacagttcc ggaagatgat
1501 ccagcagacc ttccagcagt acgcctcgct cagggaggag gagtgcgtca tgaagttctt
1561 caacactctc gccggcttcg ccaacatcga ccaggagacc taccgctgtg aactcattca
1621 aggatggaac attactgtgg acctggtcat tggccctaaa gggatccgcc agctgactag
1681 tcaggacgca aagcccacct gcctggccga gttcaagcag atcaggtcca tcaggtgcct
1741 cccgctggag gagggccagg cagtacttca gctgggcatt gaaggtgccc cccaggcctt
1801 gtccatcaaa acctcatccc tagcagaggc tgagaacatg gctgacctca tagacggcta
1861 ctgccggctg cagggtgagc accaaggctc tctcatcatc catcctagga aagatggtga
1921 gaagcggaac agcctgcccc agatccccat gctaaacctg gaggcccggc ggtcccacct
1981 ctcagagagc tgcagcatag agtcagacat ctacgcagag attcccgacg aaaccctgcg
2041 aaggcccgga ggtccacagt atggcattgc ccgtgaagat gtggtcctga atcgtattct
2101 tggggaaggc ttttttgggg aggtctatga aggtgtctac acaaatcata aaggggagaa
2161 aatcaatgta gctgtcaaga cctgcaagaa agactgcact ctggacaaca aggagaagtt
2221 catgagcgag gcagtgatca tgaagaacct cgaccacccg cacatcgtga agctgatcgg
2281 catcattgaa gaggagccca cctggatcat catggaattg tatccctatg gggagctggg
2341 ccactacctg gagcggaaca agaactccct gaaggtgctc accctcgtgc tgtactcact
2401 gcagatatgc aaagccatgg cctacctgga gagcatcaac tgcgtgcaca gggacattgc
2461 tgtccggaac atcctggtgg cctcccctga gtgtgtgaag ctgggggact ttggtctttc
2521 ccggtacatt gaggacgagg actattacaa agcctctgtg actcgtctcc ccatcaaatg
2581 gatgtcccca gagtccatta acttccgacg cttcacgaca gccagtgacg tctggatgtt
2641 cgccgtgtgc atgtgggaga tcctgagctt tgggaagcag cccttcttct ggctggagaa
2701 caaggatgtc atcggggtgc tggagaaagg agaccggctg cccaagcctg atctctgtcc
2761 accggtcctt tataccctca tgacccgctg ctgggactac gaccccagtg accggccccg
2821 cttcaccgag ctggtgtgca gcctcagtga cgtttatcag atggagaagg acattgccat
2881 ggagcaagag aggaatgctc gctaccgaac ccccaaaatc ttggagccca cagccttcca
2941 ggaaccccca cccaagccca gccgacctaa gtacagaccc cctccgcaaa ccaacctcct
3001 ggctccaaag ctgcagttcc aggttcctga gggtctgtgt gccagctctc ctacgctcac
3061 cagccctatg gagtatccat ctcccgttaa ctcactgcac accccacctc tccaccggca
3121 caatgtcttc aaacgccaca gcatgcggga ggaggacttc atccaaccca gcagccgaga
3181 agaggcccag cagctgtggg aggctgaaaa ggtcaaaatg cggcaaatcc tggacaaaca
3241 gcagaagcag atggtggagg actaccagtg gctcaggcag gaggagaagt ccctggaccc
3301 catggtttat atgaatgata agtccccatt gacgccagag aaggaggtcg gctacctgga
3361 gttcacaggg cccccacaga agcccccgag gctgggcgca cagtccatcc agcccacagc
3421 taacctggac cggaccgatg acctggtgta cctcaatgtc atggagctgg tgcgggccgt
3481 gctggagctc aagaatgagc tctgtcagct gccccccgag ggctacgtgg tggtggtgaa
3541 gaatgtgggg ctgaccctgc ggaagctcat cgggagcgtg gatgatctcc tgccttcctt
3601 gccgtcatct tcacggacag agatcgaggg cacccagaaa ctgctcaaca aagacctggc
3661 agagctcatc aacaagatgc ggctggcgca gcagaacgcc gtgacctccc tgagtgagga
3721 gtgcaagagg cagatgctga cggcttcaca caccctggct atggacgcca agaacctgct
3781 cgacgctgtg gaccaggcca aggttctggc caatctggcc cacccacctg cagagtgacg
3841 gagggtgggg gccacctgcc tgcgtcttcc gcccctgcct gccatgtacc tcccctgcct
3901 tgctgttggt catgtgggtc ttccagggag aaggccaagg ggagtcacct tcccttgcca
3961 ctttgcacga cgccctctcc ccacccctac ccctggctgt actgctcagg ctgcagctgg
4021 acagagggga ctctgggcta tggacacagg gtgacggtga caaagatggc tcagaggggg
4081 actgctgctg cctggccact gctccctaag ccagcctggt ccatgcaggg ggctcctggg
4141 ggtggggagg tgtcacatgg tgcccctagc tttatatatg gacatggcag gccgatttgg
4201 gaaccaagct attcctttcc cttcctcttc ggccctcaga tgtcccttga tgcacagaga
4261 agctggggag gagctttgtt ttgggggtca ggcagccagt gagatgaggg atgggcctgg
4321 cattcttgta cagtgtatat tgaaatttat ttaatgtgag tttggtctgg actgacagca
4381 tgtgccctcc tgagggagga cctggggcac agtccaggaa caagctaatt gggagtccag
4441 gcacaggatg ctgtgttgtc aacaaaccaa gcatcagggg gaagaagcag agagatgcgg
4501 ccaagatagg accttgggcc aaatccgctc tcttcctgcc cctctttctc tttcttcctt
4561 tactttccct tgcttttccc tcttttctta ctcctcctct ttctctcccc aacccccatt
4621 ctcatctgca cccttctttt ctcatgtgtt tgcataaaca ttcttttaac ttctttctat
4681 ttgacttgtg gttgaattaa aattgtccca tttgcaaaaa aaaaaaaaaa
//