LOCUS BC036452 3173 bp mRNA linear HUM 01-SEP-2006
DEFINITION Homo sapiens potassium voltage-gated channel, Isk-related family,
member 1, mRNA (cDNA clone MGC:33114 IMAGE:5266786), complete cds.
ACCESSION BC036452
VERSION BC036452.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3173)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3173)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (09-AUG-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 47 Row: k Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 60218914.
FEATURES Location/Qualifiers
source 1..3173
/db_xref="H-InvDB:HIT000051704"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:33114 IMAGE:5266786"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3173
/gene="KCNE1"
/gene_synonym="ISK"
/gene_synonym="JLNS"
/gene_synonym="JLNS2"
/gene_synonym="LQT5"
/gene_synonym="MinK"
/db_xref="GeneID:3753"
/db_xref="HGNC:HGNC:6240"
/db_xref="MIM:176261"
CDS 212..529
/gene="KCNE1"
/gene_synonym="ISK"
/gene_synonym="JLNS"
/gene_synonym="JLNS2"
/gene_synonym="LQT5"
/gene_synonym="MinK"
/codon_start=1
/product="KCNE1 protein"
/protein_id="AAH36452.1"
/db_xref="GeneID:3753"
/db_xref="HGNC:HGNC:6240"
/db_xref="MIM:176261"
/translation="MILSNTTAVTPFLTKLWQETVQQGGNMSGLAHRSPRSGDGKLEA
LYVLMVLGFFGFFTLGIMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLES
YRS"
BASE COUNT 807 a 840 c 765 g 761 t
ORIGIN
1 agcgggctgt ctgtggcctc agcgctcggc aggcgcgcac tcagctccac acccggctct
61 ctcggcatct cagacccggt ttcacacaat catcaggtga gccgaggatc cattggagga
121 aggcattatc tgtatccaga ggaaatagcc aggatattca gaggtgtgcc tgggaagttt
181 gagctgcagc agtggaacct taatgcccag gatgatcctg tctaacacca cagcggtgac
241 gccctttctg accaagctgt ggcaggagac agttcagcag ggtggcaaca tgtcgggcct
301 ggcccacagg tccccccgca gcggtgacgg caagctggag gccctctacg tcctcatggt
361 actgggattc ttcggcttct tcaccctggg catcatgctg agctacatcc gctccaagaa
421 gctggagcac tcgaacgacc cattcaacgt ctacatcgag tccgatgcct ggcaagagaa
481 ggacaaggcc tatgtccagg cccgggtcct ggagagctac aggtcgtgat atgtcgttga
541 aaaccatctg gccatagaac aacccaacac acaccttcct gagacgaagc cttccccatg
601 aaccccacca ctggctaaaa ctggacacat cctgcctggc aacctgattt tctaatcaca
661 ttcctctcat actctttatt gtgatggata ccactggatt tctttttggc tgttgtaagg
721 ggtggggggt ggattaatga cactgtttca ctgtttctct aaaatcacgt tcttttgtga
781 tagactgtca gtggttcccc catatctgtc cctgccttgc taaatttagc agaatccctg
841 aggacatggc ctctgagaat agcagctgca tttcccagac tcccttgcag ctagcaaggt
901 tgtgtgacta agccctggcc agtaggcatg gaagtgaaga ctgtaatgtc caagtaatcc
961 ttggaaagaa aagaacgtgc ccttaactaa ctttgtcctg cttcccagtg gctggatgtg
1021 gaggaggtgg agagcagtta tgagactggg aaagaatggg gcactcaaag agccacacac
1081 atctgggcct gggcgacgtg gatcctcctt accacccacc aggccagatt tacaggagag
1141 agaaatccac tccactcttc cttaagccac tgttattctg atctctgtta aggtcgcaga
1201 atcaatgccc ttactgatac acctacctta tgggactgaa cctaaaggca tgacatttcc
1261 atacttgtca caagcacaca ctgattctgc ccttgtcact tctgtgctca ctcttgtggc
1321 tctatcctcc tcctgccctt ccgccttcca ctcctccctt gcacccatcc tgcacacatc
1381 tccctgaaaa cacacaggca catacactca tatacataga cacacataca cacctcaatc
1441 tagaaagaac ttgctttgta cagggctgag atggaggaga aaaaaatgcc cccttcagga
1501 tgcataccaa ggggaaggtg ctcggtcact gtgggagcag ggaaaggtgc ccccactccc
1561 cgagagccag gggaaggagt ggctctgggc agagagggac acatagcact ggggtggcag
1621 gtccttttga ggtgatgggc cggttttgtg agatgaattg tatcccccaa aaagacaggt
1681 accttcaatg tgacctaatt gggaaataga gtctttgcag atgatctagt tgagatgagg
1741 tcattggggt gggccctcac ccaatatgac tggagtcctt atcggaagag ggaaattcag
1801 acacagatgc atagggaggg caccatgccg tgacagaggc agagggtgca gtgacacagc
1861 cacaaaccaa ggaaggccga ggatggatgc gcatccccat cccaagaagt cgggaagaag
1921 ccaggaaggc tcctctccca caggtttcag aggaagcaca gccctgcttg aattcaaact
1981 tttggcctcc agaactgtga gtcagtacct gttgttgaag ccacccagct taggatactc
2041 tggcagccta ctgccataca gtattgggat actatagtga gcccatgcag cacctctcac
2101 ccacccagag atggagctgc tctgccttcc agcggggcac ccggaggggc tgccccagca
2161 gatagagagg gcctccgttc tgccacctgc cttgaaaggg tctccagctg ccatatgtag
2221 cattggagtc ctctgcaatg cgacatcctg aaagctcagc tgcctgggca ttcctgaaga
2281 gtatggaata tttaaatgaa acatattttt ttaaaacctg cgcataagat aaaagcagcc
2341 cgtgtgcatc ttgggccatc ctcaaatgga cagacttggt cttgtgaggt tccagtcctt
2401 gtttcacata ataaacactg gcatggctca gcccctgagt taccacagtc cttgagatga
2461 gtggttcttt gggttacaaa gtcctctgaa agtctagtga gagctgtgat ctttgcccca
2521 cccgaataat gcatatggac accacacctt gcctgccgtg tccaggattc atgaccagta
2581 gcagcccagc tatgcctgcc acgtctcacg gcccctgtgt aagccagacc cttcttaggc
2641 agttgcatat tcccagactg aggcagggca ggtttgcaga gagagaccca gagtgcacgt
2701 gacccgcagt gtgatccctg gcacgcactg actttgatat tccaggcaca cggactggct
2761 atttatcacc acttcttttt ccccactaag attcctgtgc cttttaaggc agagggagat
2821 ccctatggcg ttagtcttcc caggccttaa agggcccttg tcttcactca caaacctctt
2881 atctcttctt ctccttcctc tacattttaa agggggagag ggaaaagtaa ccgggagaca
2941 aattgagcca catattttca gacacttgtt accatatttt aaaatctggc ttcacataca
3001 cagagtcttt gctatgcacc atgtactgtt ctaagcttct taaaaataga atctcaatta
3061 ttattttgca ggcaatactc tgtgcattca ttagctagga caacaatgca tttgcagtag
3121 tgagatttcg ttaaaaaatt aaagccattt actatggaaa aaaaaaaaaa aaa
//