LOCUS BC036447 3516 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens rhophilin, Rho GTPase binding protein 2, mRNA (cDNA
clone MGC:26769 IMAGE:4830913), complete cds.
ACCESSION BC036447
VERSION BC036447.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3516)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3516)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (09-AUG-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Sep 16, 2003 this sequence version replaced BC036447.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 34 Row: j Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 37059770.
FEATURES Location/Qualifiers
source 1..3516
/db_xref="H-InvDB:HIT000051700"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:26769 IMAGE:4830913"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3516
/gene="RHPN2"
/gene_synonym="p76RBE"
/gene_synonym="RhoBP"
/db_xref="GeneID:85415"
/db_xref="HGNC:HGNC:19974"
CDS 37..2097
/gene="RHPN2"
/gene_synonym="p76RBE"
/gene_synonym="RhoBP"
/codon_start=1
/product="rhophilin, Rho GTPase binding protein 2"
/protein_id="AAH36447.1"
/db_xref="GeneID:85415"
/db_xref="HGNC:HGNC:19974"
/translation="MTDALLPAAPQPLEKKNDGYFRKGCNPLAQTGRSKLQNQRAALN
QQILKAVRMRTGAENLLKVATNSKVREQVRLELSFVNSDLQMLKEELEGLNISVGVYQ
NTEEAFTIPLIPLGLKETKDVDFAVVLKDFILEHYSEDGYLYEDEIADLMDLRQACRT
PSRDEAGVELLMTYFIQLGFVESRFFPPTRQMGLLFTWYDSLTGVPVSQQNLLLEKAS
VLFNTGALYTQIGTRCDRQTQAGLESAIDAFQRAAGVLNYLKDTFTHTPSYDMSPAML
SVLVKMMLAQAQESVFEKISLPGIRNEFFMLVKVAQEAAKVGEVYQQLHAAMSQAPVK
ENIPYSWASLACVKAHHYAALAHYFTAILLIDHQVKPGTDLDHQEKCLSQLYDHMPEG
LTPLATLKNDQQRRQLGKSHLRRAMAHHEESVREASLCKKLRSIEVLQKVLCAAQERS
RLTYAQHQEEDDLLNLIDAPSVVAKTEQEVDIILPQFSKLTVTDFFQKLGPLSVFSAN
KRWTPPRSIRFTAEEGDLGFTLRGNAPVQVHFLDPYCSASVAGAREGDYIVSIQLVDC
KWLTLSEVMKLLKSFGEDEIEMKVVSLLDSTSSMHNKSATYSVGMQKTYSMICLAIDD
DDKTDKTKKISKKLSFLSWGTNKNRQKSASTLCLPSVGAARPQVKKKLPSPFSLLNSD
SSWY"
BASE COUNT 949 a 823 c 844 g 900 t
ORIGIN
1 agtccgccgt ccgccctccg cgcccgcgcc gctagcatga ccgacgcgct gttgcccgcg
61 gccccccagc cgctggagaa gaagaacgac ggctactttc ggaagggctg taatcccctt
121 gcacaaaccg gccggagtaa attgcagaat caaagagctg ctttgaatca gcagatcctg
181 aaagccgtgc ggatgaggac cggagcggaa aaccttctga aagtggccac aaactcaaag
241 gtgcgggagc aagtgcggct ggagctgagc ttcgtcaact cagacctgca gatgctcaag
301 gaagagctgg aggggctgaa catctcggtg ggcgtctatc agaacacaga ggaggcattt
361 acgattcccc tgattcctct tggcctgaag gaaacgaaag acgtcgactt tgcagtcgtc
421 ctcaaggatt ttatcctgga acattacagt gaagatggct atttatatga agatgaaatt
481 gcagatctta tggatctgag acaagcttgt cggacgccta gccgggatga ggccggggtg
541 gaactgctga tgacatactt catccagctg ggctttgtcg agagtcgatt cttcccgccc
601 acacggcaga tgggactcct gttcacctgg tatgactctc tcaccggggt tccggtcagc
661 cagcagaacc tgctgctgga gaaggccagt gtcctgttca acactggggc cctctacacc
721 cagattggga cccggtgtga tcggcagacg caggctgggc tggagagtgc catagatgcc
781 tttcagagag ccgcaggggt tttaaattac ctgaaagaca catttaccca tactccaagt
841 tacgacatga gccctgccat gctcagcgtg ctcgtcaaaa tgatgcttgc acaagcccaa
901 gaaagcgtgt ttgagaaaat cagccttcct gggatccgga atgaattctt catgctggtg
961 aaggtggctc aggaggctgc taaggtggga gaggtctacc aacagctaca cgcagccatg
1021 agccaggcgc cggtgaaaga gaacatcccc tactcctggg ccagcttagc ctgcgtgaag
1081 gcccaccact acgcggccct ggcccactac ttcactgcca tcctcctcat cgaccaccag
1141 gtgaagccag gcacggatct ggaccaccag gagaagtgcc tgtcccagct ctacgaccac
1201 atgccagagg ggctgacacc cttggccaca ctgaagaatg atcagcagcg ccgacagctg
1261 gggaagtccc acttgcgcag agccatggct catcacgagg agtcggtgcg ggaggccagc
1321 ctctgcaaga agctgcggag cattgaggtg ctacagaagg tgctgtgtgc cgcacaggaa
1381 cgctcccggc tcacgtacgc ccagcaccag gaggaggatg acctgctgaa cctgatcgac
1441 gcccccagtg ttgttgctaa aactgagcaa gaggttgaca ttatattgcc ccagttctcc
1501 aagctgacag tcacggactt cttccagaag ctgggcccct tatctgtgtt ttcggctaac
1561 aagcggtgga cgcctcctcg aagcatccgc ttcactgcag aagaagggga cttggggttc
1621 accttgagag ggaacgcccc cgttcaggtt cacttcctgg atccttactg ctctgcctcg
1681 gtggcaggag cccgggaagg agattatatt gtctccattc agcttgtgga ttgtaagtgg
1741 ctgacgctga gtgaggttat gaagctgctg aagagctttg gcgaggacga gatcgagatg
1801 aaagtcgtga gcctcctgga ctccacatca tccatgcata ataagagtgc cacatactcc
1861 gtgggaatgc agaaaacgta ctccatgatc tgcttagcca ttgatgatga cgacaaaact
1921 gataaaacca agaaaatctc caagaagctt tccttcctga gttggggcac caacaagaac
1981 agacagaagt cagccagcac cttgtgcctc ccatcggtcg gggctgcacg gcctcaggtc
2041 aagaagaagc tgccctcccc tttcagcctt ctcaactcag acagttcttg gtactaatgt
2101 gaggaaacaa acatgttcag gccctgaaca tttccggtgc tgactcggcc ttaaacgttt
2161 gtgccataat ggaaaatatc tatctatctg ttctcaaatc ctgtttttct catagtgtaa
2221 actcacattt gatgtgtttt tatgaaggaa agtaaccaag aaacctctag gaattagtga
2281 aaaaagaact tttttgaggt gtgttactat actgctgtaa gttatttatt atataaagta
2341 ttgtaaatag aatagtgttg aagatatgaa atatggctat ttttaatggt gacaattatg
2401 acttttagtc actattaaat tggggttacc tatatcagta caatttgtag ttgtttccag
2461 gtttggctaa taatcattcc ttaacctaga attcagatga tcctggaatt aaggcaggtc
2521 agaggactgt aatgatagaa ttaaattagt gtcactaaaa actgtcccaa agtgctgctt
2581 cctaatagga attcattaac ctaaaacaag atgttactat tatatcgata gactatgaat
2641 gctatttcta gaaaaagtct agtgccaaat ttgtcttatt aaataaaaac aatgtaggag
2701 cagcttttct tctagtttga tgtcatttaa gaattactaa cacagtggca gtgttagatg
2761 aagatgctgt ctacaaggta gataatatac tgtttgatac tcaaaacatt tttcattttg
2821 tttaaagtag aagttacata attctatatt ttaagtcttg ggtaaaaaag tagttttaca
2881 ttttataaag taaagatgta aatgattcag gtttaaagct ctatttgact tccttttttt
2941 gtttgagata gcgtcttgct gtgttgccca ggctggagtg cagtggtgtg atctcagctc
3001 agtgcaacct ccgccccctg ggatcaagcg attctcctac ctcagcctcc caaatagctg
3061 ggactacaag gtgccctcca gcatgcctgg ctgatttttg tatttttagt tgaggtgagg
3121 tttcaccatg ttggccaggc gggtttcgaa atcctgacct caaatgatcc acccacctca
3181 gcctcccaaa gtgctgggat tacaggcatg agccaccaca accgtcccac tattttactt
3241 tttaaaatga cattcctact gattgatttt tatcttgcta taagttcgat gacaccgtga
3301 atctaataag gttcactgtt gacacagtac aagttacata gctaaaatac atagcattga
3361 agactaattt taaggattga caagagttta ttttctattg tgcaatatct taaaggaagc
3421 aaccaccttt gggaaagtgt atctgctgct cctagggcca tgcttgtata catatttaaa
3481 taaacatatt catttacccg aaaaaaaaaa aaaaaa
//