LOCUS BC036375 4874 bp mRNA linear HUM 19-MAR-2009
DEFINITION Homo sapiens angiotensin I converting enzyme (peptidyl-dipeptidase
A) 1, mRNA (cDNA clone MGC:26566 IMAGE:4826875), complete cds.
ACCESSION BC036375
VERSION BC036375.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4874)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4874)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-AUG-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Sep 16, 2003 this sequence version replaced BC036375.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 33 Row: p Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 23238215
The stop codon of the CDS annotated on this record is located > 55
bases upstream of a splice junction, and therefore the mRNA is
predicted to be subject to nonsense-mediated mRNA decay (NMD).
FEATURES Location/Qualifiers
source 1..4874
/db_xref="H-InvDB:HIT000051686"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:26566 IMAGE:4826875"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..4874
/gene="ACE"
/gene_synonym="ACE1"
/gene_synonym="CD143"
/gene_synonym="DCP"
/gene_synonym="MVCD3"
/db_xref="GeneID:1636"
/db_xref="HGNC:HGNC:2707"
/db_xref="MIM:106180"
CDS 46..2265
/gene="ACE"
/gene_synonym="ACE1"
/gene_synonym="CD143"
/gene_synonym="DCP"
/gene_synonym="MVCD3"
/codon_start=1
/product="ACE protein"
/protein_id="AAH36375.1"
/db_xref="GeneID:1636"
/db_xref="HGNC:HGNC:2707"
/db_xref="MIM:106180"
/translation="MGQGWATAGLPSLLFLLLCYGHPLLVPSQEASQQVTVTHGTSSQ
ATTSSQTTTHQATAHQASAQSPNLVTDEAEASKFVEEYDRTSQVVWNEYAEANWNYNT
NITTETSKILLQKNMQIANHTLKYGTQARKFDVNQLQNTTIKRIIKKVQDLERAALPA
QELEEYNKILLDMETTYSVATVCHPNGSCLQLEPDLTNVMATSRKYEDLLWAWEGWRD
KAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSMYETPSLEQDLERLFQELQPLYL
NLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTE
AMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYN
GKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLAL
SVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSIT
KENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHE
ALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAML
SYFKPLLDWLRTENELHGEKLGWPQYNWTPNSDDFYNETETKIFLQFYDQTGIWDHGA
PHLLPPSQARGTREAPVYMSKRAASSGPPGSPKLPPAAQGHGEVPVHDLLWHPGPPV"
BASE COUNT 1211 a 1406 c 1310 g 947 t
ORIGIN
1 attggccagg ggacggtagc tgcaggactc tgctctcctg cggccatggg ccagggttgg
61 gctactgcag gacttcccag cctcctcttc ctgctgctct gctacgggca ccctctgctg
121 gtccctagcc aggaggcatc ccaacaggtg acagtcaccc atgggacaag cagccaggca
181 acaaccagca gccagacaac cacccaccag gcgacggccc accaggcatc agcccagagc
241 ccaaacctgg tgactgatga ggctgaggcc agcaagtttg tggaggaata tgaccggaca
301 tcccaggtgg tgtggaacga gtatgccgag gccaactgga actacaacac caacatcacc
361 acagagacca gcaagattct gctgcagaag aacatgcaaa tagccaacca caccctgaag
421 tacggcaccc aggccaggaa gtttgatgtg aaccagttgc agaacaccac tatcaagcgg
481 atcataaaga aggttcagga cctagaacgg gcagcgctgc ctgcccagga gctggaggag
541 tacaacaaga tcctgttgga tatggaaacc acctacagcg tggccactgt gtgccacccg
601 aatggcagct gcctgcagct cgagccagat ctgacgaatg tgatggccac atcccggaaa
661 tatgaagacc tgttatgggc atgggagggc tggcgagaca aggcggggag agccatcctc
721 cagttttacc cgaaatacgt ggaactcatc aaccaggctg cccggctcaa tggctatgta
781 gatgcagggg actcgtggag gtctatgtac gagacaccat ccctggagca agacctggag
841 cggctcttcc aggagctgca gccactctac ctcaacctgc atgcctacgt gcgccgggcc
901 ctgcaccgtc actacggggc ccagcacatc aacctggagg ggcccattcc tgctcacctg
961 ctggggaaca tgtgggcgca gacctggtcc aacatctatg acttggtggt gcccttccct
1021 tcagccccct cgatggacac cacagaggct atgctaaagc agggctggac gcccaggagg
1081 atgtttaagg aggctgatga tttcttcacc tccctggggc tgctgcccgt gcctcctgag
1141 ttctggaaca agtcgatgct ggagaagcca accgacgggc gggaggtggt ctgccacgcc
1201 tcggcctggg acttctacaa cggcaaggac ttccggatca agcagtgcac caccgtgaac
1261 ttggaggacc tggtggtggc ccaccacgaa atgggccaca tccagtattt catgcagtac
1321 aaagacttac ctgtggcctt gagggagggt gccaaccccg gcttccatga ggccattggg
1381 gacgtgctag ccctctcagt gtctacgccc aagcacctgc acagtctcaa cctgctgagc
1441 agtgagggtg gcagcgacga gcatgacatc aactttctga tgaagatggc ccttgacaag
1501 atcgccttta tccccttcag ctacctcgtc gatcagtggc gctggagggt atttgatgga
1561 agcatcacca aggagaacta taaccaggag tggtggagcc tcaggctgaa gtaccagggc
1621 ctctgccccc cagtgcccag gactcaaggt gactttgacc caggggccaa gttccacatt
1681 ccttctagcg tgccttacat caggtacttc gtcagcttca tcatccagtt ccagttccac
1741 gaggcactgt gccaggcagc tggccacacg ggccccctgc acaagtgtga catctaccag
1801 tccaaggagg ccgggcagcg cctggcgacc gccatgaagc tgggcttcag taggccgtgg
1861 ccggaagcca tgcagctgat cacgggccag cccaacatga gcgcctcggc catgttgagc
1921 tacttcaagc cgctgctgga ctggctccgc acggagaacg agctgcatgg ggagaagctg
1981 ggctggccgc agtacaactg gacgccgaac tccgatgact tctacaatga gaccgagacc
2041 aagatcttcc tgcagtttta tgaccaaaca gggatttggg accatggggc accacatctc
2101 ctgcccccat cccaagcaag aggaacaagg gaagccccag tgtacatgtc aaagagggct
2161 gcaagctctg ggcctcctgg aagccctaaa cttcctccag ctgcacaagg acatggagag
2221 gtcccagttc atgatttact ttggcaccca ggcccacctg tttaaagtca cccagttcaa
2281 ggacccggat gtgaatggca tgctgaaact cgaagtcatg gccacctcca gggacaaaga
2341 ggagctgctg tgggcctggc agggctggca ggatgccgtg ggccgccaga tctgcaccac
2401 cttcgagcac tatgtggagc tcagcaacaa ggctgcacag ctcaacggaa gaggctgctg
2461 agaaagagaa tgagaagagg ctgctgcaga caagtggaca gggaaggcct ctgacattta
2521 tccaagacct gaaagatggg caaaagacgg gaagcaagat gtgaaagaag agcagcctag
2581 gcagaggctc cgcggcagga ggagccggtg ctctggaaga cctgaaagaa gcccaggtta
2641 caaagacatg ggggccttgt ggcactccaa gtatgagtcg gataccctgg agcaagacct
2701 ggagcggcta ttccaggagc tgcggccact ctacctgaac ctgcacacct acgtgcgcag
2761 ggccctccac cgccactatg ggcccgagct catcgacctg agggggccca tccctgccca
2821 cctcctggag aacacgttgg ctcagtcctg ggtcaacatc ttagacccgg tcctgccctt
2881 cctgaagaag atcccagagg atgtcacaaa gatcatgaaa gtccagcact ggaagccaga
2941 gaaaatgttg gaagaggctg agacattctt cacctccttg gcgctgccac ctgccccacc
3001 cagtttctgg aaaaagttga tgctaatgag gccaaccgat gggcgagagg tggagtgtca
3061 catctctgcc tggaacttct accaggacga cgatttcagc taggaggctg aggcaggaga
3121 atcactggaa cctgggagcc ggaggctgca gtgagccaag atcgcaccat tgcactccag
3181 ctgggagaca cagcaagact ccgtctcaaa agaaaaaaaa aaaaaagaac aactgccaag
3241 aataaagaag tgcgcggaag tgaccacaga agacccgctc tccatcttcc acgaaatggg
3301 ccattccagt acttcctgca gtacaagaac ctctccatca tcttccgcgc aggtgccaac
3361 ccagcctttg aagaggctgt ggggtctgtg atcaccctct cggcctcctc ccacaagcac
3421 ctgctcaaca taggcctgct cagcctctag caccaggact cagaggatga ggtcaatttc
3481 ctgatgcata ttgccctgga gaagatcgcc ttcatcccct ttggctacct gatggacctc
3541 cttcgctgga aggtctttga cggcaccatc tggaaggaca tctacaatca ggagtggtgg
3601 aacctcaggt tgaaatacca gggcttgtgc cccgctattc ctcactcaga ggaagacttt
3661 gatccaggtg ccaagttcca cttttctgca ggtacttcct cagtctggtg ctccagttcc
3721 agttccacga aacactgtgc aaagcctcgg gccacatggg tccactgcac cagtgtgaca
3781 tctacaactc caagattgcc gggaagctcc tgggggatgc tctaaagctg ggctcaagca
3841 agccctggcc agaggtccta aagatgctga ctggggagtc tgaggtgtct acaaatgtct
3901 tcatgaccta cttcaaaccc ctactgacct ggctggtgac agaacatgca gcaaggggac
3961 atcttaggct ggccagactt cagctgttcc tttgaagaaa aagacacaga caaagtgaca
4021 ttcctgagtc tgaagctgga ccccaaccag gctaaatttg ggtactgggt gctgttggcc
4081 ctgggctttg tcatgtctct ggtggtgctg gggctggcct gcaggctgca gtccctggaa
4141 aaacagtcac tgactcaaga cactgagata ttcagcccac tgcccaatgc ctgcttcctg
4201 ggcatagcca tggaaccctg ccaggctgct aaaggacagt ggatgctgct gggcctctgc
4261 cttgtcctga tgctgtgctc aatcagcctg gccatctgga ttttcacaca gtaaagcagg
4321 aagcctccaa ggtaacccgg ctatgggact gcagtgccca aggaatttct gctctggtta
4381 gaaaaaggac tctgcttcag tccacttctg ctctggttag aaaaaggact ctgcttcagt
4441 ccacagtaca taaaatgtac tcagctatca gctctataag agctggatgc acatcaggag
4501 tgtgcccctc tgtaacaact ctagtcagca caggccatgg tgcacaaaag ggacttggaa
4561 aatgatggaa tgaccagcct gtccaacaga ggggcagcca ggacatctct gccctcttct
4621 catcccccag ccacagtggc caaagaggcc cccactaggc actgtggctc tgcatgacaa
4681 acacacatcc agcccaggac tctaagcctc tcacctggac tccagtaaaa accttgctga
4741 gcctccttgt ctatccttcc tcccccaccc accattgtaa agtttatgtc accagaatat
4801 ttctttcatg tctaattgct taagaacttg gttgttcatc aattaaatct agatgtccag
4861 aaaaaaaaaa aaaa
//