LOCUS BC036285 3600 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens protein kinase, cAMP-dependent, regulatory, type I,
alpha (tissue specific extinguisher 1), mRNA (cDNA clone MGC:17251
IMAGE:4340015), complete cds.
ACCESSION BC036285
VERSION BC036285.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3600)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3600)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-AUG-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Lou Staudt
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 12 Row: p Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 47132579.
FEATURES Location/Qualifiers
source 1..3600
/db_xref="H-InvDB:HIT000051663"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:17251 IMAGE:4340015"
/tissue_type="Lymph, lymphoma"
/clone_lib="NIH_MGC_85"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3600
/gene="PRKAR1A"
/gene_synonym="CAR"
/gene_synonym="CNC"
/gene_synonym="CNC1"
/gene_synonym="MGC17251"
/gene_synonym="PKR1"
/db_xref="GeneID:5573"
/db_xref="HGNC:HGNC:9388"
/db_xref="MIM:188830"
CDS 129..1274
/gene="PRKAR1A"
/gene_synonym="CAR"
/gene_synonym="CNC"
/gene_synonym="CNC1"
/gene_synonym="MGC17251"
/gene_synonym="PKR1"
/codon_start=1
/product="protein kinase, cAMP-dependent, regulatory, type
I, alpha (tissue specific extinguisher 1)"
/protein_id="AAH36285.1"
/db_xref="GeneID:5573"
/db_xref="HGNC:HGNC:9388"
/db_xref="MIM:188830"
/translation="MESGSTAASEEARSLRECELYVQKHNIQALLKDSIVQLCTARPE
RPMAFLREYFERLEKEEAKQIQNLQKAGTRTDSREDEISPPPPNPVVKGRRRRGAISA
EVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFSVSFIA
GETVIQQGDEGDNFYVIDQGETDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAK
TNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQF
EDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRP
RAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV"
BASE COUNT 997 a 628 c 787 g 1188 t
ORIGIN
1 ggtggagctg tcgcctagcc gctatcgcag agtggagcgg ggctgggagc aaagcgctga
61 gggagctcgg tacgccgccg cctcgcaccc gcagcctcgc gcccgccgcc gcccgtcccc
121 agagaaccat ggagtctggc agtaccgccg ccagtgagga ggcacgcagc cttcgagaat
181 gtgagctcta cgtccagaag cataacattc aagcgctgct caaagattct attgtgcagt
241 tgtgcactgc tcgacctgag agacccatgg cattcctcag ggaatacttt gagaggttgg
301 agaaggagga ggcaaaacag attcagaatc tgcagaaagc aggcactcgt acagactcaa
361 gggaggatga gatttctcct cctccaccca acccagtggt taaaggtagg aggcgacgag
421 gtgctatcag cgctgaggtc tacacggagg aagatgcggc atcctatgtt agaaaggtta
481 taccaaaaga ttacaagaca atggccgctt tagccaaagc cattgaaaag aatgtgctgt
541 tttcacatct tgatgataat gagagaagtg atatttttga tgccatgttt tcggtctcct
601 ttatcgcagg agagactgtg attcagcaag gtgatgaagg ggataacttc tatgtgattg
661 atcaaggaga gacggatgtc tatgttaaca atgaatgggc aaccagtgtt ggggaaggag
721 ggagctttgg agaacttgct ttgatttatg gaacaccgag agcagccact gtcaaagcaa
781 agacaaatgt gaaattgtgg ggcatcgacc gagacagcta tagaagaatc ctcatgggaa
841 gcacactgag aaagcggaag atgtatgagg aattccttag taaagtctct attttagagt
901 ctctggacaa gtgggaacgt cttacggtag ctgatgcatt ggaaccagtg cagtttgaag
961 atgggcagaa gattgtggtg cagggagaac caggggatga gttcttcatt attttagagg
1021 ggtcagctgc tgtgctacaa cgtcggtcag aaaatgaaga gtttgttgaa gtgggaagat
1081 tggggccttc tgattatttt ggtgaaattg cactactgat gaatcgtcct cgtgctgcca
1141 cagttgttgc tcgtggcccc ttgaagtgcg ttaagctgga ccgacctaga tttgaacgtg
1201 ttcttggccc atgctcagac atcctcaaac gaaacatcca gcagtacaac agttttgtgt
1261 cactgtctgt ctgaaatctg cctcctgtgc ctcccttttc tcctctcccc aatccatgct
1321 tcactcatgc aaactgcttt attttcccta cttgcagcgc caagtggcca ctggcatcgc
1381 agcttcctgt ctgtttatat attgaaagtt gcttttattg caccattttc aatttggagc
1441 attaactaaa tgctcataca cagttaaata aatagaaaga gttctatgga gactttgctg
1501 ttactgcttc tctttgtgca gtgttagtat tcaccctggg cagtgagtgc catgcttttt
1561 ggtgagggca gatcccagca cctattgaat taccatagag taatgatgta acagtgcaag
1621 attttttttt taagtgacat aattgtccag ttataagcgt atttagactg tggccatata
1681 tgctgtattt ctttgtagaa taaatggttt ctcattaaac tctaaagatt agggaaaatg
1741 gatatagaaa atcttagtat agtagaaaga catctgcctg taattaaact agtttaaggg
1801 tggaaaaatg cccatttttg ctaattatca atgggatatg attggttcag tttttttttt
1861 tccagagttg ttgtttgcca agctaatctg cctggtttta tttatatctt gttattaatg
1921 tttcttctcc aattctgaaa tacttttgag tatggctatc tatacctgcc ttttaagttt
1981 gaaactaact catagattgc aaatattggt tagtatttaa ctacatctgc ctcggctcac
2041 aaattccgat tagaccttta tccagctagt gccaaataat tgatcagatg ctgaattgag
2101 aataagaatt tgaggtctac attcttggtt gttaatttag agcgtttggt taaagtatgt
2161 ccttcagctg actccagtat aatctcctct gctcattaaa ctgattccag gagattggat
2221 ttgctgtgac tagatacaga tggagcaaat gtcctaacag agaaatagag gtgatgctgc
2281 taaagggaga aatgccaggc ggacaaagtt cagtgtcggg aattttcccc gtgacattca
2341 ctggggcatg agattttgga agaagttttt tactttggtt tagtcttttt ttccttcctt
2401 tttattcagc tagaatttct ggtgggttga tggtagggta taatgtgtct gtgttgcttc
2461 aaattggtct gaaaggctat cctgcggaaa gtcctgcttt cctatctagc atttatttct
2521 ctggcaaact tttctttctt ttctttttta aagtaaactt gtgtattgag tcttaactgt
2581 atttcagtat tttccagcct tatgtgttac attattccaa tgatacccaa cagtttattt
2641 ttattatttt tttaaacaaa atttcacagt tctgtaatgt aggcactttt attttcattg
2701 tgatttatat ataaggtaat gtagggttat atttgggagt gactgcaagc atttttccat
2761 ctgtgtgcaa ctaactgact ctgttattga tcccttctcc tgccctttcc caggtaattt
2821 aaattggtca tggtagattt ttttcataga tttgaaaaac ttttaggttg ttaccaagta
2881 tgaagtataa atctggggaa gaggttttat ttacatttta gggtgggtaa gaaagccacc
2941 ttgttacaaa ttttttaatt tccaaaataa tctatattaa atgagggttt ctgatctgta
3001 ctttgtgttt agctaccttt ttatatttaa aaaattaaaa atgaaaatta cgttcttaca
3061 agcttaaagc ttgatttgat ctttgtttaa atgccaaaat gtacttaaat gagttactta
3121 gaatgccata aaattgcagt ttcatgtatg tatataatca tgctcatgta tatttagtta
3181 cgtataatgc tttctgagtg agttttactc ttaaatcatt tggttaaatc atttggcttg
3241 ctgtttactc ccttctgtag tttttaatta aaaactttaa agataagtct acattaaaca
3301 atgatcacat ctaaagcttt atctttgtgt aatctaagta tatgtgagaa atcagaattg
3361 gcataatttg tcttagttga tattcaaggc tttaaaagtc attattcctg ggcttggtaa
3421 gtgaatttat gagatttact gctctagaaa gtatagatgg cgaaaggacc gttttgtatt
3481 gcttcctgat taccagtctg attataccat gtgtgctaat atactttttt tgttatagat
3541 tgtcttaatg gtaggtcaag taataaaaag agatgaaata atttaaaaaa aaaaaaaaaa
//