LOCUS BC036104 3091 bp mRNA linear HUM 26-JUN-2007
DEFINITION Homo sapiens spastic paraplegia 7 (pure and complicated autosomal
recessive), mRNA (cDNA clone MGC:33917 IMAGE:5274587), complete
cds.
ACCESSION BC036104
VERSION BC036104.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3091)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3091)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (31-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 48 Row: f Column: 6
This clone was selected for full length sequencing because it
passed the following selection criteria: Similarity but not
identity to protein.
FEATURES Location/Qualifiers
source 1..3091
/db_xref="H-InvDB:HIT000094258"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:33917 IMAGE:5274587"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_95"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3091
/gene="SPG7"
/gene_synonym="CAR"
/gene_synonym="PGN"
/gene_synonym="SPG5C"
/db_xref="GeneID:6687"
/db_xref="HGNC:HGNC:11237"
/db_xref="MIM:602783"
CDS 16..2403
/gene="SPG7"
/gene_synonym="CAR"
/gene_synonym="PGN"
/gene_synonym="SPG5C"
/codon_start=1
/product="spastic paraplegia 7 (pure and complicated
autosomal recessive)"
/protein_id="AAH36104.1"
/db_xref="GeneID:6687"
/db_xref="HGNC:HGNC:11237"
/db_xref="MIM:602783"
/translation="MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYM
ASRPPGDLAEAGGRALQSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFN
TSRLKQKNKEKDKSKGKAPEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALST
SGGSISWNDFVHEMLAKGEVQRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVAN
IDKFEEKLRAAEDELNIEAKDRIPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAG
MTGREGGFSAFNQLKMARFTIVDGKMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERF
LQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGAEFVEVIGGLGAARVRS
LFKEARARAPCIVYIDEIDAVGKKRSTTMSGFSNTEEEQTLNQLLVEMDGMGTTDHVI
VLASTNRADILDGALMRPGRLDRHVFIDLPTLQERREIFEQHLKSLKLTQSSTFYSQR
LAELTPGFSGADIANICNEAALHAAREGHTSVHTLNFEYAVERVLAGTAKKSKILSKE
EQKVVAFHESGHALVGWMLEHTEAVMKVSITPRTNAALGFAQMLPRDQHLFTKEQLFE
RMCMALGGRASEALSFNEVTSGAQDDLRKVTRIAYSMVKQFGMAPGIGPISFPEAQEG
LMGIGRRPFSQGLQQMMDHEARLLVAKAYRHTEKVLQDNLDKLQALANALLEKEVINY
EDIEALIGPPPHGPKKMIAPQRWIDAQREKQDLGEEETEETQQPPLGGEEPTWPK"
BASE COUNT 676 a 833 c 961 g 621 t
ORIGIN
1 ggcgttcagg ccaacatggc cgtgctgctg ctgctgctcc gtgccctccg ccggggtcca
61 ggcccgggtc ctcggccgct gtggggccca ggcccggcct ggagtccagg gttccccgcc
121 aggcccggga gggggcggcc gtacatggcc agcaggcctc cgggggacct cgccgaggct
181 ggaggccgag ctctgcagag cttacaattg agactgctaa cccctacctt tgaagggatc
241 aacggattgt tgttgaaaca acatttagtt cagaatccag tcagactctg gcaactttta
301 ggtggtactt tctattttaa cacctcaagg ttgaagcaga agaataagga gaaggataag
361 tcgaagggga aggcgcctga agaggacgaa gaggagagga gacgccgtga gcgggacgac
421 cagatgtacc gagagcggct gcgcaccttg ctggtcatcg cggttgtcat gagcctcctg
481 aatgctctca gcaccagcgg aggcagcatt tcctggaacg actttgtcca cgagatgctg
541 gccaagggcg aggtgcagcg cgtccaggtg gtgcctgaga gcgacgtggt ggaagtctac
601 ctgcaccctg gagccgtggt gtttgggcgg cctcggctag ccttgatgta ccgaatgcag
661 gttgcaaata ttgacaagtt tgaagagaag cttcgagcag ctgaagatga gctgaatatc
721 gaggccaagg acaggatccc agtttcctac aagcgaacag gattctttgg aaatgccctg
781 tactctgtgg ggatgacggc agtgggcctg gccatcctgt ggtatgtttt ccgtctggcc
841 gggatgactg gaagggaagg tggattcagt gcttttaatc agcttaaaat ggctcgtttc
901 accattgtgg atgggaagat ggggaaagga gtcagcttca aagacgtggc aggaatgcac
961 gaagccaaac tggaagtccg cgagtttgtg gattatctga agagcccaga acgcttcctc
1021 cagcttggcg ccaaggtccc aaagggcgca ctgctgctcg gcccccccgg ctgtgggaag
1081 acgctgctgg ccaaggcggt ggccacggag gctcaggtgc ccttcctggc gatggccggc
1141 gcagagttcg tggaggtcat tggaggcctc ggcgctgccc gtgtgcggag cctctttaag
1201 gaagcccgag cccgggcccc ctgcatcgtc tacatcgatg agatcgacgc ggtgggcaag
1261 aagcgctcca ccaccatgtc cggcttctcc aacacggagg aggagcagac gctcaaccag
1321 cttctggtag aaatggatgg aatgggtacc acagaccatg tcatcgtcct ggcgtccacg
1381 aaccgagctg acattttgga cggtgctctg atgaggccag gccgactgga ccggcacgtc
1441 ttcattgatc tccccacgct gcaggagagg cgggagattt ttgagcagca cctgaagagc
1501 ctgaagctga cccagtccag caccttttac tcccagcgtc tggcagagct gacaccagga
1561 ttcagtgggg ctgacatcgc caacatctgc aatgaggctg cgctgcacgc ggcgcgggag
1621 ggacacactt ccgtgcacac tctcaacttc gagtacgccg tggagcgcgt cctcgcaggg
1681 actgccaaaa agagtaagat cctgtccaag gaagaacaga aagtggttgc gtttcatgag
1741 tcgggccacg ccttggtggg ctggatgctg gagcacacgg aggccgtgat gaaggtctcc
1801 ataacccctc ggacaaacgc cgccctgggc tttgctcaga tgctccccag agaccagcac
1861 ctcttcacca aggagcagct gtttgagcgg atgtgcatgg ccctgggagg acgggcctcg
1921 gaagcactgt ccttcaacga ggtcacttct ggggcacagg acgacctgag gaaggtcacc
1981 cgcatcgcct actccatggt gaagcagttt gggatggcac ctggcatcgg gcccatctcc
2041 ttccctgagg cgcaggaggg cctcatgggc atcgggcggc gccccttcag ccaaggcctg
2101 cagcagatga tggaccatga agcaagactg ctggtggcca aggcctacag acacaccgag
2161 aaggtgctgc aggacaacct ggacaagttg caggcgctgg caaacgccct tctggaaaag
2221 gaagtgataa actatgagga cattgaggct ctcattggcc cgccgcccca tgggccgaag
2281 aaaatgatcg caccgcagag gtggatcgac gcccagaggg agaaacagga cttgggcgag
2341 gaggagaccg aagagaccca gcagcctcca cttggaggcg aagagccgac ttggcccaag
2401 tagttgggag gtgttggctg cacgtgcggg tggtccggga agtgagggct cactcagcca
2461 ccctgagttg cttttcagct gaggtttgca cttcctctcg cggccctcag tagtccctgc
2521 acagtgactt ctgagatctg ttgattgatg acccttttca tgattttaag tttctctgca
2581 gaaactactg acggagtcct gtgtttgtga gtcgtttccc ctatggggaa ggttatcagt
2641 gcttcccgag tgagcatgga acacttcgag ttcccagggt tatagacagt cgttcccagt
2701 gtggctgagg ccacccagag gcagcagagc attcagactc caaacagacc cctgttcatg
2761 ccgacgcttg cacgaccgcc ccagttcctg tggctccctc ggaatgctaa ggggatcgga
2821 catgaaagga ccctgtgagc cgattgtcct atctccagcg gccctgtcat ccagctcact
2881 catcaatggg gccagtcagg cccaggcact gggctccgga ggactcacca ctgccccctg
2941 ctgccatgtg gactggtgca agttgaggac ttcttgctgg tctagtcacg catgcagtgt
3001 tggggatgcc ttggttttta ctgctctgag aattgttgag atactttact aataaactgt
3061 gtagttggaa aatctaaaaa aaaaaaaaaa a
//