LOCUS BC035959 3014 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens cytochrome P450, family 19, subfamily A, polypeptide
1, mRNA (cDNA clone MGC:32521 IMAGE:4770068), complete cds.
ACCESSION BC035959
VERSION BC035959.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3014)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3014)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (31-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: CLONTECH
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 41 Row: p Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 13904857.
FEATURES Location/Qualifiers
source 1..3014
/db_xref="H-InvDB:HIT000051559"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:32521 IMAGE:4770068"
/tissue_type="Placenta"
/clone_lib="NIH_MGC_79"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..3014
/gene="CYP19A1"
/gene_synonym="ARO"
/gene_synonym="ARO1"
/gene_synonym="CPV1"
/gene_synonym="CYAR"
/gene_synonym="P-450AROM"
/db_xref="GeneID:1588"
/db_xref="HGNC:HGNC:2594"
/db_xref="MIM:107910"
CDS 140..1651
/gene="CYP19A1"
/gene_synonym="ARO"
/gene_synonym="ARO1"
/gene_synonym="CPV1"
/gene_synonym="CYAR"
/gene_synonym="P-450AROM"
/codon_start=1
/product="cytochrome P450, family 19, subfamily A,
polypeptide 1"
/protein_id="AAH35959.1"
/db_xref="GeneID:1588"
/db_xref="HGNC:HGNC:2594"
/db_xref="MIM:107910"
/translation="MVLEMLNPIHYNITSIVPEAMPAATMPVLLLTGLFLLVWNYEGT
SSIPGPGYCMGIGPLISHGRFLWMGIGSACNYYNRVYGEFMRVWISGEETLIISKSSS
MFHIMKHNHYSSRFGSKLGLQCIGMHEKGIIFNNNPELWKTTRPFFMKALSGPGLVRM
VTVCAESLKTHLDRLEEVTNESGYVDVLTLLRRVMLDTSNTLFLRISLDESAIVVKIQ
GYFDAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECM
DFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIK
EIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGT
NIILNIGRMHRLEFFPKPNEFTLENFAKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAI
LVTLLRRFHVKTLQGQCVESIQKIHDLSLHPDETKNMLEMIFTPRNSDRCLEH"
BASE COUNT 913 a 646 c 641 g 814 t
ORIGIN
1 agtttctgga gggctgaaca cgtggaggca aacaggaagg tgaagaagaa cttatcctat
61 caggacggaa ggtcctgtgc tcgggatctt ccagacgtcg cgactctaaa ttgccccctc
121 tgaggtcaag gaacacaaga tggttttgga aatgctgaac ccgatacatt ataacatcac
181 cagcatcgtg cctgaagcca tgcctgctgc caccatgcca gtcctgctcc tcactggcct
241 ttttctcttg gtgtggaatt atgagggcac atcctcaata ccaggtcctg gctactgcat
301 gggaattgga cccctcatct cccacggcag attcctgtgg atggggatcg gcagtgcctg
361 caactactac aaccgggtgt atggagaatt catgcgagtc tggatctctg gagaggaaac
421 actcattatc agcaagtcct caagtatgtt ccacataatg aagcacaatc attacagctc
481 tcgattcggc agcaaacttg ggctgcagtg catcggtatg catgagaaag gcatcatatt
541 taacaacaat ccagagctct ggaaaacaac tcgacccttc tttatgaaag ctctgtcagg
601 ccccggcctt gttcgtatgg tcacagtctg tgctgaatcc ctcaaaacac atctggacag
661 gttggaggag gtgaccaatg aatcgggcta tgtggacgtg ttgacccttc tgcgtcgtgt
721 catgctggac acctctaaca cgctcttctt gaggatctct ttggacgaaa gtgctatcgt
781 ggttaaaatc caaggttatt ttgatgcatg gcaagctctc ctcatcaaac cagacatctt
841 ctttaagatt tcttggctat acaaaaagta tgagaagtct gtcaaggatt tgaaagatgc
901 catagaagtt ctgatagcag aaaaaagacg caggatttcc acagaagaga aactggaaga
961 atgtatggac tttgccactg agttgatttt agcagagaaa cgtggtgacc tgacaagaga
1021 gaatgtgaac cagtgcatat tggaaatgct gatcgcagct cctgacacca tgtctgtctc
1081 tttgttcttc atgctatttc tcattgcaaa gcaccctaat gttgaagagg caataataaa
1141 ggaaatccag actgttattg gtgagagaga cataaagatt gatgatatac aaaaattaaa
1201 agtgatggaa aacttcattt atgagagcat gcggtaccag cctgtcgtgg acttggtcat
1261 gcgcaaagcc ttagaagatg atgtaatcga tggctaccca gtgaaaaagg ggacaaacat
1321 tatcctgaat attggaagga tgcacagact cgagtttttc cccaaaccca atgaatttac
1381 tcttgaaaat tttgcaaaga atgttcctta taggtacttt cagccatttg gctttgggcc
1441 ccgtggctgt gcaggaaagt acatcgccat ggtgatgatg aaagccatcc tcgttacact
1501 tctgagacga ttccacgtga agacattgca aggacagtgt gttgagagca tacagaagat
1561 acacgacttg tccttgcacc cagatgagac taaaaacatg ctggaaatga tctttacccc
1621 aagaaactca gacaggtgtc tggaacacta gagaaggctg gtcagtacct actctggagc
1681 atttctcatc agtagttcac atacaaatca tccatccttg ccaatagtgt catcctcaca
1741 gtgaacactc agtggcccat ggcattttat aggcatacct cctatgggtt gtcaccaagc
1801 taggtgctat tggtcatctg ctcctgttca caccagagaa ccaggctaca agagaaaaag
1861 cagaggccaa gagtttgagg gagaaatagt cggtgaagaa accgtatcca taaagacccg
1921 attccaccaa atgtgctttg agaaggatag gccttcatta acaaaatgta tgtctggttc
1981 cccagtagag ctctactgcc tcaacccaag gggattttta tgtctggggc agaaacactc
2041 aagttgatta gaaagaccag gccaatgtca gggtacctgg ggccaaaccc acctgctagt
2101 gtgaattaaa gtactttaat tttgttttct gtggaggtgg aaaagcaaca ttcatagtct
2161 ttggagaaat gcttagaaat tcagcatttg acccttgctg tgaattaagc ccaattaatt
2221 cctgtttgtc tacatatgat ctgtctgtgg caaaagttta atcagaggaa attctttccc
2281 agtctgtcga tttatgcctc agccacttgc ctgtgctaca attcattgtg ttacctgtag
2341 attcaggtaa tacaaactat atataatcat caagtaatac aaactaattt agtaatagcc
2401 tgggttaagt attattaggg ccctgtgtct gctgtagaaa aaaaaattca catgatgcac
2461 ttcaaattca aataaaaatc cttttggcat gttcccattt ttgcttagct caattagtgt
2521 ggctaaccaa gagataactg taaatgtgac attgatttgc tcttactaca gcttcagtga
2581 ttgggggagg aaaagtccca acccaatggg ctcaaacttc taaggggtac tcctctcatc
2641 cccttatcct tctccctcga cattttctcc ctctttcttc ccatgacccc aaagccaagg
2701 gcaacagatc agtaaagaac gtggtcagag tagaacccct gaagtatttt ttaatcctac
2761 ctcaaaattt aacagttacc tgagagattt aacattatct agttcattga atcattgtat
2821 gtggtcatgg ataaattgca caccttggaa ttcgctttct aaaggaaatc aaatgaatgg
2881 aggaactttc caaacaccac tttacttgtg ttatatagcc aatataacta tctctactga
2941 atgtcattga aaaactaaaa aattaaactt atttacaaat aggtcaaaaa aaaaaaaaaa
3001 aaaaaaaaaa aaaa
//