LOCUS BC035588 4152 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens ATPase, Ca++ transporting, cardiac muscle, slow twitch
2, mRNA (cDNA clone MGC:45367 IMAGE:5503508), complete cds.
ACCESSION BC035588
VERSION BC035588.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4152)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4152)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (31-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 69 Row: h Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 27886536.
FEATURES Location/Qualifiers
source 1..4152
/db_xref="H-InvDB:HIT000051427"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:45367 IMAGE:5503508"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..4152
/gene="ATP2A2"
/gene_synonym="DD"
/gene_synonym="MGC45367"
/gene_synonym="SERCA2"
/db_xref="GeneID:488"
/db_xref="HGNC:HGNC:812"
/db_xref="MIM:108740"
CDS 111..3239
/gene="ATP2A2"
/gene_synonym="DD"
/gene_synonym="MGC45367"
/gene_synonym="SERCA2"
/codon_start=1
/product="ATPase, Ca++ transporting, cardiac muscle, slow
twitch 2"
/protein_id="AAH35588.1"
/db_xref="GeneID:488"
/db_xref="HGNC:HGNC:812"
/db_xref="MIM:108740"
/translation="MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAE
EGKTLLELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANA
IVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVP
ADIRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGK
AMGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINI
GHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVR
SLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAPI
GEVHKDDKPVNCHQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVE
KMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSM
SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATH
DNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMIT
GDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELNPSAQRDACLNARCFARVEPSH
KSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFS
TIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVT
DGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFI
AADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLVTIEMCNALNS
LSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKI
SLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVLLIMPLVIWVY
STDTNFSDMFWS"
BASE COUNT 1111 a 928 c 987 g 1126 t
ORIGIN
1 ccacgcgtcc gcctgggctc ccggggtggc acgagcccgc ggccggagtg cgaggcggag
61 gcgaggaggc cgcggggacg ggaggcgagg ccggccgggc ccccgaagcc atggagaacg
121 cgcacaccaa gacggtggag gaggtgctgg gccacttcgg cgtcaacgag agtacggggc
181 tgagcctgga acaggtcaag aagcttaagg agagatgggg ctccaacgag ttaccggctg
241 aagaaggaaa aaccttgctg gaacttgtga ttgagcagtt tgaagacttg ctagttagga
301 ttttattact ggcagcatgt atatcttttg ttttggcttg gtttgaagaa ggtgaagaaa
361 caattacagc ctttgtagaa ccttttgtaa ttttactcat attagtagcc aatgcaattg
421 tgggtgtatg gcaggaaaga aatgctgaaa atgccatcga agcccttaag gaatatgagc
481 ctgaaatggg caaagtgtat cgacaggaca gaaagagtgt gcagcggatt aaagctaaag
541 acatagttcc tggtgatatt gtagaaattg ctgttggtga caaagttcct gctgatataa
601 ggttaacttc catcaaatct accacactaa gagttgacca gtcaattctc acaggtgaat
661 ctgtctctgt catcaagcac actgatcccg tccctgaccc acgagctgtc aaccaagata
721 aaaagaacat gctgttttct ggtacaaaca ttgctgctgg gaaagctatg ggagtggtgg
781 tagcaactgg agttaacacc gaaattggca agatccggga tgaaatggtg gcaacagaac
841 aggagagaac accccttcag caaaaactag atgaatttgg ggaacagctt tccaaagtca
901 tctcccttat ttgcattgca gtctggatca taaatattgg gcacttcaat gacccggttc
961 atggagggtc ctggatcaga ggtgctattt actactttaa aattgcagtg gccctggctg
1021 tagcagccat tcctgaaggt ctgcctgcag tcatcaccac ctgcctggct cttggaactc
1081 gcagaatggc aaagaaaaat gccattgttc gaagcctccc gtctgtggaa acccttggtt
1141 gtacttctgt tatctgctca gacaagactg gtacacttac aacaaaccag atgtcagtct
1201 gcaggatgtt cattctggac agagtggaag gtgatacttg ttcccttaat gagtttacca
1261 taactggatc aacttatgca cctattggag aagtgcataa agatgataaa ccagtgaatt
1321 gtcaccagta tgatggtctg gtagaattag caacaatttg tgctctttgt aatgactctg
1381 ctttggatta caatgaggca aagggtgtgt atgaaaaagt tggagaagct acagagactg
1441 ctctcacttg cctagtagag aagatgaatg tatttgatac cgaattgaag ggtctttcta
1501 aaatagaacg tgcaaatgcc tgcaactcag tcattaaaca gctgatgaaa aaggaattca
1561 ctctagagtt ttcacgtgac agaaagtcaa tgtcggttta ctgtacacca aataaaccaa
1621 gcaggacatc aatgagcaag atgtttgtga agggtgctcc tgaaggtgtc attgacaggt
1681 gcacccacat tcgagttgga agtactaagg ttcctatgac ctctggagtc aaacagaaga
1741 tcatgtctgt cattcgagag tggggtagtg gcagcgacac actgcgatgc ctggccctgg
1801 ccactcatga caacccactg agaagagaag aaatgcacct tgaggactct gccaacttta
1861 ttaaatatga gaccaatctg accttcgttg gctgcgtggg catgctggat cctccgagaa
1921 tcgaggtggc ctcctccgtg aagctgtgcc ggcaagcagg catccgggtc atcatgatca
1981 ctggggacaa caagggcact gctgtggcca tctgtcgccg catcggcatc ttcgggcagg
2041 atgaggacgt gacgtcaaaa gctttcacag gccgggagtt tgatgaactc aacccctccg
2101 cccagcgaga cgcctgcctg aacgcccgct gttttgctcg agttgaaccc tcccacaagt
2161 ctaaaatcgt agaatttctt cagtcttttg atgagattac agctatgact ggcgatggcg
2221 tgaacgatgc tcctgctctg aagaaagccg agattggcat tgctatgggc tctggcactg
2281 cggtggctaa aaccgcctct gagatggtcc tggcggatga caacttctcc accattgtgg
2341 ctgccgttga ggaggggcgg gcaatctaca acaacatgaa acagttcatc cgctacctca
2401 tctcgtccaa cgtcggggaa gttgtctgta ttttcctgac agcagccctt ggatttcccg
2461 aggctttgat tcctgttcag ctgctctggg tcaatctggt gacagatggc ctgcctgcca
2521 ctgcactggg gttcaaccct cctgatctgg acatcatgaa taaacctccc cggaacccaa
2581 aggaaccatt gatcagcggg tggctctttt tccgttactt ggctattggc tgttacgtcg
2641 gcgctgctac cgtgggtgct gctgcatggt ggttcattgc tgctgacggt ggtccaagag
2701 tgtccttcta ccagctgagt catttcctac agtgtaaaga ggacaacccg gactttgaag
2761 gcgtggattg tgcaatcttt gaatccccat acccgatgac aatggcgctc tctgttctag
2821 taactataga aatgtgtaac gccctcaaca gcttgtccga aaaccagtcc ttgctgagga
2881 tgcccccctg ggagaacatc tggctcgtgg gctccatctg cctgtccatg tcactccact
2941 tcctgatcct ctatgtcgaa cccttgccac tcatcttcca gatcacaccg ctgaacgtga
3001 cccagtggct gatggtgctg aaaatctcct tgcccgtgat tctcatggat gagacgctca
3061 agtttgtggc ccgcaactac ctggaacctg gtaaagagtg tgtgcagcct gccaccaaat
3121 cctgctcgtt ctcggcatgc accgatggga tttcctggcc gtttgtgctg ctcataatgc
3181 ccctggtgat ctgggtctat agcacagaca ctaactttag cgatatgttc tggtcttgac
3241 tgacagtttt ccataaagaa gatgtttaac ttaatcaatt aattttttta ttgtttaaag
3301 caactgtcta tttctgctga attttcacat gaacatactg gctggtgatg gaggtttcat
3361 actctagatt ttgttttgct ttttctgact ccagtggggc aagattttcc ttttttatac
3421 acataattaa agtgtccatt gacatgtaca gagaactaac actattttat gcaaatattt
3481 ttttgtagat gaaaaagcat gtacagtgtt ctgtttaata ctcatccttg tataaaaaaa
3541 atagttgagc cagcagacat tgtcagcaaa ttaattggca gcagatttta ggaaatgaat
3601 gtgtgtggtt ttttttctaa aactaaatag catgtattgt gtcttttgca tgatgatccg
3661 gatttaattt gatatcacag tctaattttt attcataagc caatttttct gcactgagca
3721 gagtcttgct acctcagtca gtattgtttt ggtttgctac ttccctcacc cactttggcc
3781 tccgttcacc ccaccccacc ccacctctcc ccaccttacc cccgccccgc ttggcttctt
3841 ctttaggatt gtgatggttc gttctgttta catcagtttt aacgagaggt atgcctgtac
3901 tcgcttgtgc agaaaacatt gttccagatt caatcgactg ggtttatgtc ccttcacata
3961 gtttttaagg ttatttattt aaatgtctaa tgtattttat tgtaacagac attgttttgc
4021 caacattgcc tatttcagtg gcacgtcatc tagttttaaa aaaataaaac attttaaatg
4081 gacagagaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
4141 aaaaaaaaaa aa
//