LOCUS BC035509 1015 bp mRNA linear HUM 11-DEC-2003
DEFINITION Homo sapiens DIX domain containing 1, mRNA (cDNA clone
IMAGE:4898802), partial cds.
ACCESSION BC035509
VERSION BC035509.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1015)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1015)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (31-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC035509.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 39 Row: j Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis, Similarity but not identity to protein.
FEATURES Location/Qualifiers
source 1..1015
/db_xref="H-InvDB:HIT000093950"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4898802"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..>1015
/gene="DIXDC1"
/gene_synonym="KIAA1735"
/db_xref="GeneID:85458"
CDS 114..>1015
/gene="DIXDC1"
/gene_synonym="KIAA1735"
/codon_start=1
/product="DIXDC1 protein"
/protein_id="AAH35509.1"
/db_xref="GeneID:85458"
/translation="MLACLTRGNLLDVLQEGFNEQQLQAYVAWVNAQLKKRPAVKPVQ
DLRQDLRDGVILAYLIEIVAGEKLSGVQLSPGNQQEMKNNVEKVLQFVASKKIRMHQT
SAKDIVDGNLKSIMRLVLALAAHFKPGSSRTVNQGRDSRAPLQSHRPHCATAVAQGAA
AALADVCHDMSRSGRDVFRYRQRNSSMDEEIENPYWSVRALVQQYEGQQRSPSESSCS
SLTSPSPIHSAKSESIITQSEEKADFVIIPAEGIENRTEGTDSPLSRDWRPGSPGTYL
ETSWEEQLLEQQEYLEKKKKKKKK"
misc_feature 174..494
/gene="DIXDC1"
/gene_synonym="KIAA1735"
/note="CH; Region: Calponin homology (CH) domain. The CH
domain is found in both cytoskeletal proteins and signal
transduction proteins. The CH domain is involved in actin
binding in some members of the family. However in
calponins there is evidence that the CH domain is not
involved in its actin binding activity. Most proteins have
two copies of the CH domain, however some proteins such as
calponin have only a single copy"
/db_xref="CDD:pfam00307"
BASE COUNT 290 a 240 c 300 g 185 t
ORIGIN
1 ccggagggat cccaatgagc tgagccgaga gcctttgtgt gcagagggag gaggaggagg
61 cggcggcggc cgccgggctg gagaccccgc ccggggagcc cccagcagga acaatgctag
121 cctgcctgac ccgagggaac ttactggacg tcctgcagga gggcttcaat gagcaacagc
181 tgcaggccta tgtggcctgg gtgaatgcac agctgaagaa gaggccagca gtgaagcctg
241 tgcaggacct gcgacaagat ctccgggatg gggtgatcct ggcatatctc atcgagattg
301 ttgcaggaga aaagctgagt ggggtacagc tgagtcccgg taaccaacag gagatgaaga
361 ataatgtgga gaaagtgcta cagtttgtgg cctctaaaaa gattcgtatg caccagactt
421 cggctaaaga tattgtggat ggaaacctga agtctatcat gaggctggtc cttgccttgg
481 cagctcattt caaacctggc tccagcagga cggtgaacca aggacgggac tccagagccc
541 ctctgcaaag tcaccgacca cactgtgcca ctgctgttgc ccagggagca gctgctgctc
601 tggccgatgt gtgtcatgac atgtcccgat caggacggga tgtctttcga tatagacaga
661 ggaacagcag catggatgag gaaattgaga atccatactg gagtgtgcgg gccctagtgc
721 agcagtacga agggcaacaa aggtccccgt ctgaatccag ctgctccagc ctgacttcac
781 ccagtccaat ccacagtgca aagagcgagt ccattataac ccagtcagaa gagaaggcag
841 attttgtgat tattcccgct gaaggaatag agaacagaac agaagggaca gattctccat
901 tatctcgaga ctggcggcca gggagccctg gaacctatct ggagacctca tgggaagaac
961 agctgttgga acaacaagaa tatttagaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//