LOCUS BC035507 3222 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens down-regulator of transcription 1, TBP-binding
(negative cofactor 2), mRNA (cDNA clone MGC:29766 IMAGE:4555131),
complete cds.
ACCESSION BC035507
VERSION BC035507.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3222)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3222)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (31-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 19, 2003 this sequence version replaced BC035507.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 39 Row: d Column: 9
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 45006969.
FEATURES Location/Qualifiers
source 1..3222
/db_xref="H-InvDB:HIT000093948"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:29766 IMAGE:4555131"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_46"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3222
/gene="DR1"
/gene_synonym="NC2"
/gene_synonym="NC2-BETA"
/db_xref="GeneID:1810"
/db_xref="HGNC:HGNC:3017"
/db_xref="MIM:601482"
CDS 726..1256
/gene="DR1"
/gene_synonym="NC2"
/gene_synonym="NC2-BETA"
/codon_start=1
/product="down-regulator of transcription 1, TBP-binding
(negative cofactor 2)"
/protein_id="AAH35507.1"
/db_xref="GeneID:1810"
/db_xref="HGNC:HGNC:3017"
/db_xref="MIM:601482"
/translation="MASSSGNDDDLTIPRAAINKMIKETLPNVRVANDARELVVNCCT
EFIHLISSEANEICNKSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRR
KASSRLENLGIPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASA
SNQAGSSQDEEDDDDI"
BASE COUNT 917 a 617 c 675 g 1013 t
ORIGIN
1 gagcggcttc ctgcaaacct tccctggcat ctggagggac caccgttgcc gcgtcttcgg
61 cttccacgat ctgcgttcgg gctacgcggc cacggcggca gccactgcga ctcccactgt
121 gcctggctct gtccatatta gttcccaggc ggccgtcgcc gttccagcag cggcagcggc
181 agcggcagcg gcggacatgt tgtgaggcgg cggcgcgggt gtctgaagga tggtttggcc
241 gaggcggcgg caacggctgc tggcggcggc ggcagcggca gcggggcctc gggctctata
301 gagccgagcc cgctgggtac ccgcccggta ccgcggcgag gccagtgccc ctggatcttg
361 cctctgctcc gacgccgttg gggaccagtt aggcgacagc gcccgcccct ctgaggagac
421 acgaaggtgg ttccccagcc gctcaaattt ccggaccacc gcgctttccc ctcctcagcc
481 tgggctgtgc tctctctaga atcctcgggc ccccactttc ttcccaaact catcctaaat
541 ctctcacaca cgcgagtgtt cccagccctc aagccagctg ctcctccgtt cattttctgc
601 accctcttcg caaagcaccc cccgggatca ctctccgagg gcgacttttt gagaaatctc
661 ggtggagtag tggaccagag ctggggagtt tttaaaagcc ggggcgcgag aaacaggaag
721 gtactatggc ttcctcgtct ggcaacgatg atgatctcac tatccccaga gctgctatca
781 ataaaatgat caaagagact cttcctaatg tccgggtggc caacgatgct cgagagctgg
841 tggtgaactg ctgcactgaa ttcattcacc ttatatcttc tgaagccaat gagatttgta
901 acaaatcgga aaagaagacc atctcaccag agcatgtcat acaagcacta gaaagtttgg
961 gatttggctc ttacatcagt gaagtaaaag aagtcttgca agagtgtaaa acagtagcat
1021 taaaaagaag aaaggccagt tctcgtttgg aaaaccttgg cattcctgaa gaagagttat
1081 tgagacagca acaagaatta tttgcaaaag ctagacagca acaagcagaa ttggcccaac
1141 aggaatggct tcaaatgcag caagctgccc aacaagccca gcttgctgct gcctcagcca
1201 gtgcatctaa tcaggcggga tcttctcagg atgaagaaga tgatgatgat atctgaaatt
1261 caccagctga gtttctattt cttctataaa tgtttttccc tgcacaacaa aaacagtgaa
1321 agaaatgctt atctgtaatt ttgtatgcat cttggtggac ttgtcattgg tattctaggg
1381 atgtctgcta ttaagtttca tctattgtgt gctatacatg taaaaactgt ctctttgaac
1441 tattgaaaat ttaaggttca gtataatatc aattttgaat ttttaatggt gtttatgaaa
1501 ttttagatag cagcgagtcc ttcgtttgat caataaacag tgttacagat aacttcaagt
1561 ttataaaaat acagtgaaat ttctacaaag ctctaaatct gcatttgcat ttcctctgcc
1621 cttttaacta aactaaaact tgtgaatttt aaattattaa ggggggggtg ctgtgtgaat
1681 cagtagacat tggattgggt tggtgaaaga gttcagttct gtagtatctg aatttgtctt
1741 ttaaaatgag tacatatata ggcaataaat atatatgctc agatcaatat acttgtttag
1801 aaaaacttca agacattcaa aaactaggaa ggagtatgtt taatagtatt tgtataaatt
1861 tggtggttat gtttttttat tttgtttctg ttttgtgtag aggtaaaaac tatagtttta
1921 ttacagcata attcattttg agctccacta tgacatttca aagactgccc agtttggaag
1981 tctgtcatga tttttactct ttcactccaa ttcagtaatt gttgatagta ttacttacct
2041 agtccatcca tactcatatt attcaaatat ataggtggta cttttgaaac aattacattg
2101 gttctcttgg tttaactgag gtttatgaat attcaaacct ttgctggggg aaagaaatga
2161 aagttaatga gcatgcttgc tatgagagag ggatttttaa tttaacttgt agttatagtt
2221 tacttattgt ttttagaatt acttttacat tttcccaact agatggccta gagtccaaca
2281 ttaccttttg agatgacatt attgtctcca taattgagtg atagctttaa aaaaaagatt
2341 agttttgctt aagaagttat gttacaactg atcagcccta tatgaattaa ctgatcagcc
2401 ctatatgaaa cataagttgt gttataactt atcagccgta tatggaacat aaatagtttc
2461 tacctgcttg ttagagaagc tttaatttgg ttctaataaa tacagtatgg tagtgtttat
2521 aggaatccag gatgttgaag aaatggcata atgtctatat tttggaaaca gaaaggaaaa
2581 gtcacttaag atagtattaa gtaattaaat tcctatgtca gttgccaaat cttttaaact
2641 tatgtattca ccaagcccaa aaatagattg tggctcccag gattccaatt ttaattggag
2701 agctaagtaa gtaaagtttt ataactgtta ggtttcttaa tgatcatatt ttgcagtttt
2761 agtaaaaggg aaatattgtt atacatttat taaatatact tcccccatga agtgaaaagg
2821 ttaattttgc tgaatgtttt aagttgaagt tacttcatgg atgtcatacc catgaagtgc
2881 atttggatga gatagaagaa attgtttttt aaaaagttta agtaccaaag gtagtctagt
2941 ctagaacgat aagttaatac gtgttggctt ttctaatttg tactgtaaca tccttatact
3001 ttctatttta agtatatctg tttcttaagt aaacaactta gatattttcc acaccttttt
3061 ttttttctga tgcagagttc aggttaatat tttactgcat ctgataatgt attatacgtt
3121 tgaagcctag tgacttttca ttttgacatt cttgtgattt catatgctgt attcttcaag
3181 caataaaatt gtgatgtgtt ttataaaaaa aaaaaaaaaa aa
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