LOCUS BC035492 4077 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens mitogen-activated protein kinase 6, mRNA (cDNA clone
MGC:5156 IMAGE:2984834), complete cds.
ACCESSION BC035492
VERSION BC035492.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4077)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4077)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (31-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Sep 16, 2003 this sequence version replaced BC035492.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 3 Row: l Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 16306569.
FEATURES Location/Qualifiers
source 1..4077
/db_xref="H-InvDB:HIT000051394"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:5156 IMAGE:2984834"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_10"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..4077
/gene="MAPK6"
/gene_synonym="ERK3"
/gene_synonym="HsT17250"
/gene_synonym="p97MAPK"
/db_xref="GeneID:5597"
/db_xref="HGNC:HGNC:6879"
/db_xref="MIM:602904"
CDS 755..2920
/gene="MAPK6"
/gene_synonym="ERK3"
/gene_synonym="HsT17250"
/gene_synonym="p97MAPK"
/codon_start=1
/product="mitogen-activated protein kinase 6"
/protein_id="AAH35492.1"
/db_xref="GeneID:5597"
/db_xref="HGNC:HGNC:6879"
/db_xref="MIM:602904"
/translation="MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDK
RVAIKKIVLTDPQSVKHALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELN
SVYIVQEYMETDLANVLEQGPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFI
NTEDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAA
GCIFAEMLTGKTLFAGAHELEQMQLILESIPVVHEEDRQELLSVIPVYIRNDMTEPHK
PLTQLLPGISREAVDFLEQILTFSPMDRLTAEEALSHPYMSIYSFPMDEPISSHPFHI
EDEVDDILLMDETHSHIYNWERYHDCQFSEHDWPVHNNFDIDEVQLDPRALSDVTDEE
EVQVDPRKYLDGDREKYLEDPAFDTNYSTEPCWQYSDHHENKYCDLECSHTCNYKTRS
SSYLDNLVWRESEVNHYYEPKLIIDLSNWKEQSKEKSDKKGKSKCERNGLVKAQIALE
EASQQLAGKEREKNQGFDFDSFIAGTIQLSSQHEPTDVVDKLNDLNSSVSQLELKSLI
SKSVSQEKQEKGMANLAQLEALYQSSWDSQFVSGGEDCFFINQFCEVRKDEQVEKENT
YTSYLDKFFSRKEDTEMLETEPVEDGKLGERGHEEGFLNNSGEFLFNKQLESIGIPQF
HSPVGSPLKSIQATLTPSAMKSSPQIPHQTYSSILKHLN"
BASE COUNT 1277 a 725 c 821 g 1254 t
ORIGIN
1 gcggcgactg cggcaaagcg agagcctcgg agacgccgct gccgccagca cagccggaga
61 cctgagccga cactgggggc agtccgcgag ccccgcactc tctcgatgag tcggagaagt
121 cccgttgtat cagagtaaga tggacggtag ctttgattgt gattgtggtg agctggagcc
181 acctgatcac taacaaaaga catcttctgt taaccaacag ccgccagggc ttcctgttga
241 aataaatata tagcaacaaa ggaaaaaaag aagcaaaacg gaaatagtgc ttaccagcac
301 cttagaatga tgctgctcag gaccagtcca acactgaatg tatctgcact gtgaggagaa
361 tgttcataga agcctgttgt gtgcatattt attcacattt ttgttaaatg ttaaatcgtt
421 tagcacggta atctgagtgc acagtatgtc atttcattcc gtttgagttt cttgttttcg
481 ttaaatgtct gcagagttgc tgcccctttc ttgaactatg agtactgcaa tctttttaat
541 tctcaatatg aatagagctt tttgagcttt aaatctaagg ggaactcgac aggcctgttt
601 ggcatatgca atgaacatca agaaaccatc ttgctgtgga agcataatta tttttcttct
661 ccctttttga aagatctttc cttttgatgc cagttttctt ccttgtttac acaagttcaa
721 tttgaaagga aaaggcaata gtaagggttt caaaatggca gagaaatttg aaagtctcat
781 gaacattcat ggttttgatc tgggttctag gtatatggac ttaaaaccat tgggttgtgg
841 aggcaatggc ttggtttttt ctgctgtaga caatgactgt gacaaaagag tagccatcaa
901 gaaaattgtc cttactgatc cccagagtgt caaacatgct ctacgtgaaa tcaaaattat
961 tagaagactt gaccatgata acattgtgaa agtgtttgag attcttggtc ccagtggaag
1021 ccaattaaca gacgatgtgg gctctcttac ggaactgaac agtgtttaca ttgttcagga
1081 gtacatggag acagacttgg ctaatgtgct ggagcagggc cctttactgg aagagcatgc
1141 caggcttttc atgtatcagc tgctacgggg gctcaagtat attcactctg caaatgtact
1201 gcacagagat ctcaaaccag ctaatctttt cattaatacg gaagacttgg tgctgaagat
1261 aggtgacttt ggtcttgcac ggatcatgga tcctcattat tcccataagg gtcatctttc
1321 tgaaggattg gttactaaat ggtacagatc tccacgtctt ttactttctc ctaataatta
1381 tactaaagcc attgacatgt gggctgcagg ctgcatcttt gctgaaatgc tgactggtaa
1441 aacccttttt gcaggtgcac atgaacttga acagatgcag ctgattttag aatctattcc
1501 tgttgtacat gaggaagatc gtcaggagct tctcagcgta attccagttt acattagaaa
1561 tgacatgact gagccacaca aacctttaac tcagctgctt ccaggaatta gtcgagaagc
1621 agtggatttc ctggaacaaa ttttgacatt tagccccatg gatcggttaa cagcagaaga
1681 agcactctcc catccttaca tgagcatata ttcttttcca atggatgagc caatttcaag
1741 ccatcctttt catattgaag atgaagttga tgatattttg cttatggatg aaactcacag
1801 tcacatttat aactgggaaa ggtatcatga ttgtcagttt tcagagcatg attggcctgt
1861 acataacaac tttgatattg atgaagttca gcttgatcca agagctctgt ccgatgtcac
1921 tgatgaagaa gaagtacaag ttgatccccg aaaatatttg gatggagatc gggaaaagta
1981 tctggaggat cctgcttttg ataccaatta ctctactgag ccttgttggc aatactcaga
2041 tcatcatgaa aacaaatatt gtgatctgga gtgtagccat acttgtaact acaaaacgag
2101 gtcatcatca tatttagata acttagtttg gagagagagt gaagttaacc attactatga
2161 acccaagctt attatagatc tttccaattg gaaagaacaa agcaaagaaa aatctgataa
2221 gaaaggcaaa tcaaaatgtg aaaggaatgg attggttaaa gcccagatag cgctagagga
2281 agcatcacag caactggctg gaaaagaaag ggaaaagaat cagggatttg attttgattc
2341 ctttattgca ggaactattc agcttagttc ccagcatgag cctactgatg ttgttgataa
2401 attaaatgac ttgaatagct cagtgtccca actagaattg aaaagtttga tatcaaagtc
2461 agtaagccaa gaaaaacagg aaaaaggaat ggcaaatctg gctcaattag aagccttgta
2521 ccagtcttct tgggacagcc agtttgtgag tggtggggag gactgttttt tcataaatca
2581 gttttgtgag gtaaggaagg atgaacaagt tgagaaggaa aacacttaca ctagttactt
2641 ggacaagttc tttagcagga aagaagatac tgaaatgcta gaaactgagc cagtagagga
2701 tgggaagctt ggggagagag gacatgagga aggatttctg aacaacagtg gggagttcct
2761 ctttaacaag cagctcgagt ccataggcat cccacagttt cacagtccag ttgggtcacc
2821 acttaagtca atacaggcca cattaacacc ttctgctatg aaatcttccc ctcaaattcc
2881 tcatcaaaca tacagcagca ttctgaaaca tctgaactaa aacactcagc agacatttat
2941 ctttgtattc ttcatgaaat gtgttttgtc tttttttatt actagtgttt aagtcatttt
3001 ttacttgaat cagatggtgt catttagtaa ggattttatg agttcttgtt ttttaaaatc
3061 cagactttct ttttctacat gtgagatagt tttcatttta actggcatgt catttgcaca
3121 caaaaataaa gactagagca aaataatgca acgcaggagg agaaaagaaa tgcactaaga
3181 caagaacatt ctctcataga acattgatct gttttacagg aaacaaacct tgccttgaaa
3241 tttacacagt gagactgtac ataattgcat gaaaatagct atttttttcc taagacattt
3301 ttcattcatg aatattttca agtttttcat actgtacaca tttcttaaaa cacatgatac
3361 cagcagcaac tgaaaatgaa tgccgaattt ggtacacatg tgttatctac ctcaaggtaa
3421 caagagtatg tggcaaaaca tataccaccc atagtgcttc acaaaatgca cttctattta
3481 gccagcgttt attgtagtaa actattctta ataaaactca ctcactgttt ataaatgttc
3541 tggtatgcat tctttatagt gaagtgttaa tacatcacat cttatttatt ttagcaaatc
3601 agtatatttt ctgtatttaa ttataaaaaa ttaacttagt ttttaaaatt tatttgcaaa
3661 tatacttttt ccatttggca ctatggtttg ttgcctacct agctgcatct ataatgtcag
3721 cttatcctaa ggctgtccac gtacttaatt tacttaagtg ttcattttaa gtaacgtgct
3781 cactgtgtat aggaatttgt attttggagg tgcttgatct atctacaaag aaaaattaat
3841 taggaattac tttattataa aatgctccta gaagtcttaa ttgtgtttat tttttaaaaa
3901 aacaaatgtt agacttgtgt gcatggaagt aattaaggta catcattatt gtagtttgaa
3961 agttgtacat gataagacat tttgttttta ctgtatgttt ttactgaatg atctattccc
4021 catcccaagg caagcatgaa taaaattagg ttaaacgtaa aaaaaaaaaa aaaaaaa
//