LOCUS BC035404 4142 bp mRNA linear HUM 04-JUN-2004
DEFINITION Homo sapiens PTK2 protein tyrosine kinase 2, mRNA (cDNA clone
MGC:34721 IMAGE:4999680), complete cds.
ACCESSION BC035404
VERSION BC035404.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4142)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4142)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (31-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Sep 16, 2003 this sequence version replaced BC035404.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 52 Row: e Column: 20.
FEATURES Location/Qualifiers
source 1..4142
/db_xref="H-InvDB:HIT000051391"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:34721 IMAGE:4999680"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_10"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..4142
/gene="PTK2"
/gene_synonym="FADK"
/gene_synonym="FAK"
/gene_synonym="FAK1"
/gene_synonym="pp125FAK"
/db_xref="GeneID:5747"
/db_xref="MIM:600758"
CDS 32..3052
/gene="PTK2"
/gene_synonym="FADK"
/gene_synonym="FAK"
/gene_synonym="FAK1"
/gene_synonym="pp125FAK"
/codon_start=1
/product="PTK2 protein"
/protein_id="AAH35404.1"
/db_xref="GeneID:5747"
/db_xref="MIM:600758"
/translation="MAAAYLDPNLNHTPNSSTKTHLGTGMERSPGAMERVLKVFHYFE
SNSEPTTWASIIRHGDATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDM
GVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIA
DQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAK
TLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCALGSSWIISVELAIGP
EEGISYLTDKGCNPTHLADFTQVQTIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSL
TIAENMADLIDGYCRLVNGTSQSFIIRPQKEGERALPSIPKLANSEKQGMRTHAVSVS
ETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALA
VAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELR
SFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFG
LSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQ
GVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEE
EKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTN
HYQDSTVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSI
DREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSYNEGV
KLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLA
LRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKK
QMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH"
BASE COUNT 1262 a 870 c 942 g 1068 t
ORIGIN
1 atatgacaga tacctagcat ctagcaaaat aatggcagct gcttaccttg accccaactt
61 gaatcacaca ccaaattcga gtactaagac tcacctgggt actggtatgg aacgttctcc
121 tggtgcaatg gagcgagtat taaaggtctt tcattatttt gaaagcaata gtgagccaac
181 cacctgggcc agtattatca ggcatggaga tgctactgat gtcaggggca tcattcagaa
241 gatagtggac agtcacaaag taaagcatgt ggcctgctat ggattccgcc tcagtcacct
301 gcggtcagag gaggttcact ggcttcacgt ggatatgggc gtctccagtg tgagggagaa
361 gtatgagctt gctcacccac cagaggagtg gaaatatgaa ttgagaattc gttatttgcc
421 aaaaggattt ctaaaccagt ttactgaaga taagccaact ttgaatttct tctatcaaca
481 ggtgaagagc gattatatgt tagagatagc tgatcaagtg gaccaggaaa ttgctttgaa
541 gttgggttgt ctagaaatac ggcgatcata ctgggagatg cggggcaatg cactagaaaa
601 gaagtctaac tatgaagtat tagaaaaaga tgttggttta aagcgatttt ttcctaagag
661 tttactggat tctgtcaagg ccaaaacact aagaaaactg atccaacaaa catttagaca
721 atttgccaac cttaatagag aagaaagtat tctgaaattc tttgagatcc tgtctccagt
781 ctacagattt gataaggaat gcttcaagtg tgctcttggt tcaagctgga ttatttcagt
841 ggaactggca atcggcccag aagaaggaat cagttaccta acggacaagg gctgcaatcc
901 cacacatctt gctgacttca ctcaagtgca aaccattcag tattcaaaca gtgaagacaa
961 ggacagaaaa ggaatgctac aactaaaaat agcaggtgca cccgagcctc tgacagtgac
1021 ggcaccatcc ctaaccattg cggagaatat ggctgaccta atagatgggt actgccggct
1081 ggtgaatgga acctcgcagt catttatcat cagacctcag aaagaaggtg aacgggcttt
1141 gccatcaata ccaaagttgg ccaacagcga aaagcaaggc atgcggacac acgccgtctc
1201 tgtgtcagaa acagatgatt atgctgagat tatagatgaa gaagatactt acaccatgcc
1261 ctcaaccagg gattatgaga ttcaaagaga aagaatagaa cttggacgat gtattggaga
1321 aggccaattt ggagatgtac atcaaggcat ttatatgagt ccagagaatc cagctttggc
1381 ggttgcaatt aaaacatgta aaaactgtac ttcggacagc gtgagagaga aatttcttca
1441 agaagcctta acaatgcgtc agtttgacca tcctcatatt gtgaagctga ttggagtcat
1501 cacagagaat cctgtctgga taatcatgga gctgtgcaca cttggagagc tgaggtcatt
1561 tttgcaagta aggaaataca gtttggatct agcatctttg atcctgtatg cctatcagct
1621 tagtacagct cttgcatatc tagagagcaa aagatttgta cacagggaca ttgctgctcg
1681 gaatgttctg gtgtcctcaa atgattgtgt aaaattagga gactttggat tatcccgata
1741 tatggaagat agtacttact acaaagcttc caaaggaaaa ttgcctatta aatggatggc
1801 tccagagtca atcaattttc gacgttttac ctcagctagt gacgtatgga tgtttggtgt
1861 gtgtatgtgg gagatactga tgcatggtgt gaagcctttt caaggagtga agaacaatga
1921 tgtaatcggt cgaattgaaa atggggaaag attaccaatg cctccaaatt gtcctcctac
1981 cctctacagc cttatgacga aatgctgggc ctatgacccc agcaggcggc ccaggtttac
2041 tgaacttaaa gctcagctca gcacaatcct ggaggaagag aaggctcagc aagaagagcg
2101 catgaggatg gagtccagaa gacaggccac agtgtcctgg gactccggag ggtctgatga
2161 agcaccgccc aagcccagca gaccgggtta tcccagtccg aggtccagcg aaggatttta
2221 tcccagccca cagcacatgg tacaaaccaa tcattaccag gactctacag tattggacct
2281 gcgagggatt gggcaagtgt tgccaaccca tctgatggaa gagcgtctaa tccgacagca
2341 acaggaaatg gaagaagatc agcgctggct ggaaaaagag gaaagatttc tgaaacctga
2401 tgtgagactc tctcgaggca gtattgacag ggaggatgga agtcttcagg gtccgattgg
2461 aaaccaacat atatatcagc ctgtgggtaa accagatcct gcagctccac caaagaaacc
2521 gcctcgccct ggagctcccg gtcatctggg aagccttgcc agcctcagca gccctgctga
2581 cagctacaac gagggtgtca agcttcagcc ccaggaaatc agcccccctc ctactgccaa
2641 cctggaccgg tcgaatgata aggtgtacga gaatgtgacg ggcctggtga aagctgtcat
2701 cgagatgtcc agtaaaatcc agccagcccc accagaggag tatgtcccta tggtgaagga
2761 agtcggcttg gccctgagga cattattggc cactgtggat gagaccattc ccctcctacc
2821 agccagcacc caccgagaga ttgagatggc acagaagcta ttgaactctg acctgggtga
2881 gctcatcaac aagatgaaac tggcccagca gtatgtcatg accagcctcc agcaagagta
2941 caaaaagcaa atgctgactg ctgctcacgc cctggctgtg gatgccaaaa acttactcga
3001 tgtcattgac caagcaagac tgaaaatgct tgggcagacg agaccacact gagcctcccc
3061 taggagcacg tcttgctacc ctcttttgaa gatgttctct agccttccac cagcagcgag
3121 gaattaaccc tgtgtcctca gtcgccagca cttacagctc caactttttt gaatgaccat
3181 ctggttgaaa aatctttctc atataagttt aaccacactt tgatttgggt tcattttttg
3241 ttttgttttt ttcaatcatg atattcagaa aaatccagga tccaaaatgt ggcgtttttc
3301 taagaatgaa aattatatgt aagcttttaa gcatcatgaa gaacaattta tgttcacatt
3361 aagatacgtt ctaaaggggg atggccaagg ggtgacatct taattcctaa actaccttag
3421 ctgcatagtg gaagaggaga gcatgaagca aagaattcca ggaaacccaa gaggctgaga
3481 attcttttgt ctaccataga attattatcc agactggaat ttttgtttgt tagaacaccc
3541 ttcagttgca atatgctaat cccactttac aaagaatata aaagctatat tttgaagact
3601 tgagttattt cagaaaaaac tacagccctt tttgtcttac ctgcctttta ctttcgtgtg
3661 gatatgtgaa gcattgggtc gggaactagc tgtagaacac aactaaaaac tcatgtcttt
3721 tttcacagaa taatgtgcca gttttttgta gcaatgatat ttctcttgga agcagaaatg
3781 ctttgtacca gagcacctcc aaactgcatt gaggagaagt tccagaacca tccccttttt
3841 ccatttttat ataatttata aagaaagatt aaagccatgt tgactatttt acagccactg
3901 gagttaacta acccttcctt gtatctgtct tcccaggaga gaatgaagca aaacaggaat
3961 ttggttttct tttgatgtcc agttacacca tccattctgt taattttgaa aaaatatacc
4021 ctccctttag tttgttgggg gatataaatt attctcagga agaatataat gaactgtaca
4081 gttactttga cctattaaaa aggtgttacc agtaaagttc ttgttgtaaa aaaaaaaaaa
4141 aa
//