LOCUS BC035055 3736 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 4,
mRNA (cDNA clone MGC:41866 IMAGE:5259426), complete cds.
ACCESSION BC035055
VERSION BC035055.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3736)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3736)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (31-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 73 Row: a Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 34452722.
FEATURES Location/Qualifiers
source 1..3736
/db_xref="H-InvDB:HIT000051319"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:41866 IMAGE:5259426"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_95"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3736
/gene="GABRA4"
/db_xref="GeneID:2557"
/db_xref="HGNC:HGNC:4078"
/db_xref="MIM:137141"
CDS 113..1777
/gene="GABRA4"
/codon_start=1
/product="gamma-aminobutyric acid (GABA) A receptor, alpha
4"
/protein_id="AAH35055.1"
/db_xref="GeneID:2557"
/db_xref="HGNC:HGNC:4078"
/db_xref="MIM:137141"
/translation="MVSAKKVPAIALSAGVSFALLRFLCLAVCLNESPGQNQKEEKLC
TENFTRILDSLLDGYDNRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQT
WIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTI
LYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTKGPEKSVEVPKES
SSLVQYDLIGQTVSSETIKSITGEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQV
SFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSAL
IEFAAVNYFTNIQMEKAKRKTSKPPQEVPAAPVQREKHPEAPLQNTNANLNMRKRTNA
LVHSESDVGNRTEVGNHSSKSSTVVQESSKGTPRSYLASSPNPFSRANAAETISAARA
LPSASPTSIRTGYMPRKASVGSASTRHVFGSRLQRIKTTVNTIGATGKLSATPPPSAP
PPSGSGTSKIDKYARILFPVTFGAFNMVYWVVYLSKDTMEKSESLM"
BASE COUNT 1161 a 696 c 732 g 1147 t
ORIGIN
1 agcggagtgt gcgcacgccg cgggagcctc tctgccctct cctcgcaccc tgctcagggc
61 atctgaagag cctggaaacg tgaacaggct tgaagtatgg catgttgcaa agatggtttc
121 tgccaagaag gtacccgcga tcgctctgtc cgccggggtc agtttcgccc tcctgcgctt
181 cctgtgcctg gcggtttgtt taaacgaatc cccaggacag aaccaaaagg aggagaaatt
241 gtgcacagaa aatttcaccc gcatcctgga cagtttgctc gatggttatg acaacaggct
301 gcgtcctgga tttgggggtc ctgttacaga agtgaaaact gacatatatg tcaccagctt
361 tggacctgtt tctgatgttg aaatggaata cacaatggat gtgttcttca ggcagacatg
421 gattgacaaa agattaaaat atgacggccc cattgaaatt ttgagattga acaatatgat
481 ggtaacgaaa gtgtggaccc ctgatacttt cttcaggaat ggaaagaaat ctgtctcaca
541 taatatgaca gctccaaata agctttttag aattatgaga aatggtacta ttttatacac
601 aatgagactc accataagtg cggagtgtcc catgagattg gtggattttc ccatggatgg
661 tcatgcatgc cctttgaaat tcgggagtta tgcctatcca aagagtgaga tgatctatac
721 ctggacaaaa ggtcctgaga aatcagttga agttccgaag gagtcttcca gcttagttca
781 atatgatttg attgggcaaa ccgtatcaag tgaaaccatc aaatcaatta cgggtgaata
841 tattgttatg acggtttact tccacctcag acggaagatg ggttatttta tgattcagac
901 ctatattccg tgcattatga cagtgattct ttctcaagtt tcattttgga taaataaaga
961 atcagttccc gctaggactg tatttggaat aacaactgtc ctcaccatga ccacactaag
1021 catcagtgca cgacattctt tgcccaaagt gtcctatgct accgccatgg actggttcat
1081 agctgtctgc tttgcttttg tattttcggc ccttatcgag tttgctgctg tcaactattt
1141 caccaatatt caaatggaaa aagccaaaag gaagacatca aagccccctc aggaagttcc
1201 cgctgctcca gtgcagagag agaagcatcc tgaagcccct ctgcagaata caaatgccaa
1261 tttgaacatg agaaaaagaa caaatgcttt ggttcactct gaatctgatg ttggcaacag
1321 aactgaggtg ggaaaccatt caagcaaatc ttccacagtt gttcaagaat cttctaaagg
1381 cacacctcgg tcttacttag cttccagtcc aaacccattc agccgtgcaa atgcagctga
1441 aaccatatct gcagcaagag cacttccatc tgcttctcct acttctatcc gaactggata
1501 tatgcctcga aaggcttcag ttggatctgc ttctactcgt cacgtgtttg gatcaagact
1561 gcagaggata aagaccacag ttaataccat aggggctact gggaagttgt cagctactcc
1621 tcctccatcg gctccaccac cttctggatc tggcacaagt aaaatagaca aatatgcccg
1681 tattctcttt ccagtcacat ttggggcatt taacatggtt tattgggttg tttatttatc
1741 taaggacact atggagaaat cagaaagtct aatgtaattt cgttgctata gtagtttgct
1801 aaaagatgat gaaaatgcag aatgtctttt taaatgtttt taaatataaa caaatattct
1861 ttactaaaat aaaaactctg tgtaattttt ccatttaaag atataagcca gttattggga
1921 gagttaatta attcctgagt gaaaaagtga actatgtttt ttttcagaaa aattatttta
1981 aaagaactca gcattcagtt agatagaata cacaccatcc tggaaagttg ggataagaga
2041 aatagagcta ttagagacaa gtggcgcata ttttttcatt gatatttgaa aacagactat
2101 gacattttaa aaatctgccc tatgagtatc aacctgccac cctaaatttc ccagtggcac
2161 tacccttaac cagaattgtt tattagatgt catatgcagt gacctttggt gatcttctta
2221 ggaacttcaa gaaaaggaat tttcctgtta aattaaacat tggcaaaagg aaatggaata
2281 gtataaacac tgatcaatag agtaaaatat ctgctgcata aaaaactaag acaaagacca
2341 gaggaaatat gttccctttc ttatgttggc taaacagtac ttaacagttg acttgaaatt
2401 ttgttctctg agccaaagtt taactcattg tatgaattct ttttcatggt agttcattca
2461 gttatgtgtt tatttactac atagttattc agagcctact gtgttccagg aactatgcta
2521 gaaactgtct ctctaggaaa gctcttgcac ctttatctac aatattactt aaaaagtaga
2581 acagtcaatg catgccaaag aaccataaac tagcagagga cattgcattc tttagtgaag
2641 gacatttatt tagagtctga caacatattc aaaatatttt tcagcctcta ctgatagtgg
2701 ataacaaata tatttgttca cataaccact ttgatgtcag tacaacttca gcaattggtt
2761 ttcaaaatag atgagaatat ggtacagatt gttctataag tgaaaagcat tatgtacttg
2821 aaagtaaaaa tcagggcaat ataagactta atagattaac tgtcgcaaat ttgatcagag
2881 tcacagagta gaatttgatc agaatcacag aatcatcaga cataggaact gagcgcaggc
2941 tttttcaggt gctttcccca agatagatct agatattagc tagtgaaatg ctaaattttg
3001 aagagttttg tgtccgtagt tctgtaattc tgggcagtca tcatgttggt ttttttggga
3061 gtttttttaa ggtttaataa ctaaggggaa tattttaaaa ttaagagagc agcaaatgaa
3121 aggagtaaag aaaaaaatag ctgtcgggta ggatgccact gactctgcta tgtgatttat
3181 cagggttttc atctactgac ttctttctca ttaggtaggc ttaacaactt acttgagaat
3241 tttgcaactg tctatgcagc tgaatctaag tatggttttt tgtcatattg cctctagatt
3301 ttcttctgtg cttctctcta tctgctctgg aatggatgag tgaatgtgtt ctgggtgttt
3361 tagggaacat attgatagaa atgaccacct tgcagacaaa atctctctct ctctttttgt
3421 ttttatagaa aagaagtgat agtagttaat tggcatcgat ttttcagata ttgcactacc
3481 ttataatggt tgtttttgat acctgaaaat tgtgcaaatg ccaaatatta attgtaagtc
3541 atatctgaga aatcattctt ggctgtcttt ctaggtattc catagaatca acacatttta
3601 aggctgaaag atactgtcga aatcacccag tcccaacccc ccaatttaaa attgattcta
3661 gtaaaattag gtccagtaac acctgtatat atgtatatat ttaataaaga gtacttgtac
3721 aaaaaaaaaa aaaaaa
//