LOCUS BC035031 4396 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens GA binding protein transcription factor, alpha subunit
60kDa, mRNA (cDNA clone MGC:33827 IMAGE:5264778), complete cds.
ACCESSION BC035031
VERSION BC035031.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4396)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4396)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (31-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 25, 2003 this sequence version replaced BC035031.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 47 Row: i Column: 9
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 34452720.
FEATURES Location/Qualifiers
source 1..4396
/db_xref="H-InvDB:HIT000051311"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:33827 IMAGE:5264778"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_95"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..4396
/gene="GABPA"
/gene_synonym="E4TF1-60"
/gene_synonym="E4TF1A"
/gene_synonym="NFT2"
/gene_synonym="NRF2"
/gene_synonym="NRF2A"
/db_xref="GeneID:2551"
/db_xref="HGNC:HGNC:4071"
/db_xref="MIM:600609"
CDS 221..1585
/gene="GABPA"
/gene_synonym="E4TF1-60"
/gene_synonym="E4TF1A"
/gene_synonym="NFT2"
/gene_synonym="NRF2"
/gene_synonym="NRF2A"
/codon_start=1
/product="GA binding protein transcription factor, alpha
subunit 60kDa"
/protein_id="AAH35031.1"
/db_xref="GeneID:2551"
/db_xref="HGNC:HGNC:4071"
/db_xref="MIM:600609"
/translation="MTKREAEELIEIEIDGTEKAECTEESIVEQTYAPAECVSQAIDI
NEPIGNLKKLLEPRLQCSLDAHEICLQDIQLDPERSLFDQGVKTDGTVQLSVQVISYQ
GIEPKLNILEIVKPADTVEVVIDPDAHHAESEAHLVEEAQVITLDGTKHITTISDETS
EQVTRWAAALEGYRKEQERLGIPYDPIQWSTDQVLHWVVWVMKEFSMTDIDLTTLNIS
GRELCSLNQEDFFQRVPRGEILWSHLELLRKYVLASQEQQMNEIVTIDQPVQIIPASV
QSATPTTIKVINSSAKAAKVQRAPRISGEDRSSPGNRTGNNGQIQLWQFLLELLTDKD
ARDCISWVGDEGEFKLNQPELVAQKWGQRKNKPTMNYEKLSRALRYYYDGDMICKVQG
KRFVYKFVCDLKTLIGYSAAELNRLVTECEQKKLAKMQLHGIAQPVTAVALSTASLQT
EKDN"
BASE COUNT 1433 a 725 c 849 g 1389 t
ORIGIN
1 agggcctggg aggcgggagg ggggttgggg cttctcagcg ccgattccgc gggaagggcc
61 ctgggacctc acacttctag tcgcgggagc tgcaggtctt acccggagag acgctgcacg
121 tggagccctc gccgctgccg ttctcagccg gctctggagt gcgggcgggg gcgacagggc
181 cgattccgga gtgggactga tcctttgaaa tactccagcc atgactaaaa gagaagcaga
241 ggagctgata gaaattgaga ttgatggaac agagaaagca gagtgcacag aagaaagcat
301 tgtagaacaa acctacgcgc cagctgaatg tgtaagccag gccatagaca tcaatgaacc
361 aataggcaat ttaaagaaac tgctagaacc aagactacag tgttctttgg atgctcatga
421 aatttgtctg caagatatcc agctggatcc agaacgaagt ttatttgacc aaggagtaaa
481 aacagatgga actgtacagc ttagtgtaca ggtaatttct taccaaggaa ttgaaccaaa
541 gttaaacatc cttgaaattg ttaaacctgc ggacactgtt gaggttgtta ttgatccaga
601 tgcccaccat gctgaatcag aagcacatct tgttgaagaa gctcaagtga taactcttga
661 tggcacaaaa cacatcacaa ccatttcaga tgaaacttca gaacaagtga caagatgggc
721 tgctgcactg gaaggctata ggaaagaaca agaacgcctt gggataccct atgatcccat
781 acagtggtcc acagaccaag tcctgcattg ggtggtttgg gtaatgaagg aattcagcat
841 gaccgatata gacctcacca cactcaacat ttcggggaga gaattatgta gtctcaacca
901 agaagatttt tttcagcggg ttcctcgggg agaaattctc tggagtcatc tggaacttct
961 ccgaaaatat gtattggcaa gtcaagaaca acagatgaat gaaatagtta caattgatca
1021 acctgtgcaa attattccag catcagtgca atctgctaca cctactacca ttaaagttat
1081 aaatagtagt gcgaaagcag ccaaagtaca aagagcgccg aggatttcag gagaagatag
1141 aagctcacct gggaacagaa caggaaacaa tggccaaatc caactatggc agtttttgct
1201 agaacttctt actgataagg acgctcgaga ctgcatttct tgggttggtg atgaaggtga
1261 atttaagcta aatcagcctg aactggttgc acagaaatgg ggacagcgta aaaataagcc
1321 tacgatgaac tatgagaaac tcagtcgtgc attaagatat tattacgatg gggacatgat
1381 ttgtaaagtt caaggcaaga gatttgtgta caagtttgtc tgtgacttga agactcttat
1441 tggatacagt gcagcggagt tgaaccgttt ggtcacagaa tgtgaacaga agaaacttgc
1501 aaagatgcag ctccatggaa ttgcccagcc agtcacagca gtagctctgt ctactgcttc
1561 tctgcaaacg gaaaaggata attgagcccc aggacattct gagactccaa agtctttctt
1621 aaaatgttta gagcaagtat agctcttacc tttattactg aatttgaatc ttcttttatt
1681 tctaggctgt acagtctgat gcatgatttt tttataaata tttcatactc ttgtgaattt
1741 ggatcttttt actttgagca tatattttag aatatgtgta tgttaaagga tctccacaat
1801 gtctgcagtg tgaaggcagg ttcattgtgg aatagtttaa cagtcaggaa ggctaaactg
1861 gtcagtatta atgtgtagcc ctaccaaaaa tagccagtag tatctgaaaa tgaaaaataa
1921 atgaagtatc tctaggaaac agtctggctt aactattttt gaaaatataa ctgtttcccc
1981 tctctgctgc tttagatgtt gctttacata gaaccagaaa atgggatttc tcagctaaag
2041 catgtgtgcc tgtttcatct aatcaagcag agctaaaatg ttcataccga ataaatttat
2101 attaataaat tactaaacta agagtatcag gttatttata tatttgcaag caaaggacag
2161 taagaagttg actggcaaaa gagcagtgct gaaggaggag atccaggttt aaatctggct
2221 tattaactca agccaatttt aaggattttc tgtatagatt actcatgtca gaccaagaat
2281 ttaaattatt ttgagagagg catttaattc taataaacca gctgttataa aaattataaa
2341 atgatctctg tttttcctgt cagagattta aaaaactgaa aaggtatacc tcaacccaaa
2401 aataaaggtt tgttttggtt tgttatggct tcctttttta aaaaattacc ctgtagtgcc
2461 agtttattat gcaaagcagc ttatattcct ttgtttctga taaaatgaag actttaaatc
2521 agtcagtagt actttacctt tcaaggcatt agtaaattac ttgcaaatag ttttaaaagg
2581 aaaatacgac ctttgttata ggcagtcttc tctttaagac aatacttttc cacttgtttt
2641 ccttttccat attatatatg tgtattcata tagctgtata catattcagt tgatcatttt
2701 ataaacatat gaaggcataa agatatacag aagaaaaatt attaaacaac tcattttaag
2761 attcaaatta actaattcct gcatatatga cattccttac ataagcgaac actaaacaaa
2821 aatggctaga aatgtctttt tctttctttt ctctctttgt tgtttaaggt attaagcacg
2881 aattattaca tgagactggc agatagctat taatcctctt acagatttga gaaagttgat
2941 tctcaaatat ttatgcacct tctccttcat tgttttcttt aaatctgtcc tcttaaaaag
3001 cttcttaaga gctcagttaa tgcttttgac ttaactagga gaaaaaggca tgataataca
3061 ggcaagatgg cattgttagc aattctggta gtggtttgga atgaatccta agaggcaggg
3121 atcttaagga caaggaagag aagagagaga gggagggatc tttgatctct ttctctggta
3181 atcttaatgc ataattttac taaaacatgt tctcaattca ttcatattat taagctcttc
3241 ctgcagttga tatctgagca gagtaagatt tgtatttcca tttttacttt tttgaaagag
3301 aatatatgga cagattattg gtacaatttg ggcactgtgg ttttaagaat atctgagtaa
3361 aataacaata tgaaataata aacagaagct ctaacgtcag gtaacaaata gacagcaaga
3421 aaggttttgc accatcctct tacggcctag agagttgaca agttgcttgt agttttaaaa
3481 aaataataaa gtataccctt ctggtatatc atcaagagct taagaatctt ggctttcata
3541 tttaaaatgc ttttggggag acatatatta aaattttagc caagatgata gacatgtctc
3601 aattatatat gtgtgtgtat gtttttaaag ctaaaaacat tacttttaga tccctagaat
3661 gaaaattttt ttctcatcta tgcaattccc atatggtttt ttttaaatca tattttattc
3721 attttctccc tttagcaatt ttcattttat ttctcataat ttgaacagag acagttctca
3781 tacatgatca gatgcttttt ttttcttctt accttcattt atgcatgaca taggtaatgt
3841 gactaatttc tccagttgat tcaagaaact cattactttg cctcaaatta tatgtaaaat
3901 atttgtttta cttaggttac agttatcaga aaggtagttt ttttcttcta ttaaaatata
3961 acattgtgaa agaaaataaa atttatgcta ttctttgctt tgtttttata aatgaatttt
4021 tcatagaatt tacagtatat tcaaaggaag aaagataaaa ttattggtca tcatttgtac
4081 cttagaagta caagaattta agtaaaagaa atgttcattt ttgttttaaa atttgttttc
4141 catgtgaagt ttttattgag ccaactttca tacatatctt gctagcctaa agtctaaata
4201 tttgtgttgg catcagaaaa acaaatgagg cagaattgct atgtgtggtt gatcttcaga
4261 taaattgact gatcacagtt atttttgtat cagtctatgt tattaggaaa aattgtttag
4321 ttgttttctc ccctgattaa tggtgatatt caagtatgat acaaaaagaa ttgtaccacc
4381 aaaaaaaaaa aaaaaa
//