LOCUS BC034757 1760 bp mRNA linear HUM 01-APR-2004
DEFINITION Homo sapiens Indian hedgehog homolog (Drosophila), mRNA (cDNA clone
IMAGE:5182642), partial cds.
ACCESSION BC034757
VERSION BC034757.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1760)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1760)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (24-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 50 Row: d Column: 17.
FEATURES Location/Qualifiers
source 1..1760
/db_xref="H-InvDB:HIT000051225"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:5182642"
/tissue_type="Colon, Kidney, Stomach, adult, whole pooled"
/clone_lib="NIH_MGC_116"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..1760
/gene="IHH"
/gene_synonym="BDA1"
/gene_synonym="HHG2"
/db_xref="GeneID:3549"
/db_xref="MIM:600726"
CDS <1..955
/gene="IHH"
/gene_synonym="BDA1"
/gene_synonym="HHG2"
/codon_start=2
/product="IHH protein"
/protein_id="AAH34757.2"
/db_xref="GeneID:3549"
/db_xref="MIM:600726"
/translation="ENTGADRLMTQRCKDRLNSLAISVMNQWPGVKLRVTEGWDEDGH
HSEESLHYEGRAVDITTSDRDRNKYGLLARLAVEAGFDWVYYESKAHVHCSVKSEHSA
AAKTGGCFPAGAQVRLESGARVALSAVRPGDRVLAMGEDGSPTFSDVLIFLDREPHRL
RAFQVIETQDPPRRLALTPAHLLFTADNHTEPAARFRATFASHVQPGQYVLVAGVPGL
QPARVAAVSTHVALGAYAPLTKHGTLVVEDVVASCFAAVADHHLAQLAFWPLRLFHSL
AWGSWTPGEGVHWYPQLLYRLGRLLLEEGSFHPLGMSGAGS"
misc_feature 2..286
/gene="IHH"
/gene_synonym="BDA1"
/gene_synonym="HHG2"
/note="HH_signal; Region: Hedgehog amino-terminal
signaling domain. For the carboxyl Hint module, see
pfam01079. Hedgehog is a family of secreted signal
molecules required for embryonic cell differentiation"
/db_xref="CDD:pfam01085"
misc_feature 293..877
/gene="IHH"
/gene_synonym="BDA1"
/gene_synonym="HHG2"
/note="Hint; Region: Hint module. This is an alignment of
the Hint module in the Hedgehog proteins. It does not
include any Inteins which also possess the Hint module"
/db_xref="CDD:pfam01079"
BASE COUNT 327 a 540 c 538 g 355 t
ORIGIN
1 ggagaacaca ggcgccgacc gcctcatgac ccagcgctgc aaggaccgcc tgaactcgct
61 ggctatctcg gtgatgaacc agtggcccgg tgtgaagctg cgggtgaccg agggctggga
121 cgaggacggc caccactcag aggagtccct gcattatgag ggccgcgcgg tggacatcac
181 cacatcagac cgcgaccgca ataagtatgg actgctggcg cgcttggcag tggaggccgg
241 ctttgactgg gtgtattacg agtcaaaggc ccacgtgcat tgctccgtca agtccgagca
301 ctcggccgca gccaagacag gcggctgctt ccctgccgga gcccaggtac gcctggagag
361 tggggcgcgt gtggccttgt cagccgtgag gccgggagac cgtgtgctgg ccatggggga
421 ggatgggagc cccaccttca gcgatgtgct cattttcctg gaccgcgagc ctcacaggct
481 gagagccttc caggtcatcg agactcagga ccccccacgc cgcctggcac tcacacccgc
541 tcacctgctc tttacggctg acaatcacac ggagccggca gcccgcttcc gggccacatt
601 tgccagccac gtgcagcctg gccagtacgt gctggtggct ggggtgccag gcctgcagcc
661 tgcccgcgtg gcagctgtct ctacacacgt ggccctcggg gcctacgccc cgctcacaaa
721 gcatgggaca ctggtggtgg aggatgtggt ggcatcctgc ttcgcggccg tggctgacca
781 ccacctggct cagttggcct tctggcccct gagactcttt cacagcttgg catggggcag
841 ctggaccccg ggggagggtg tgcattggta cccccagctg ctctaccgcc tggggcgtct
901 cctgctagaa gagggcagct tccacccact gggcatgtcc ggggcaggga gctgaaagga
961 ctccaccgct gccctcctgg aactgctgta ctgggtccag aagcctctca gccaggaggg
1021 agctggccct ggaagggacc tgagctgggg gacactggct cctgccatct cctctgccat
1081 gaagatacac cattgagact tgactgggca acaccagcgt cccccacccc cgtcgtggtg
1141 tagtcataga gctgcaagct gagctggcga ggggatggtt gttgacccct ctctcctaga
1201 gaccttgagg ctggcacggc gactcccaac tcagcctgct ctcactacga gttttcatac
1261 tctgcctccc ccattgggga gggcccattc catccatctt aggccccttt gggtgggctt
1321 gcgcctcagt tgatgctgct aaattccctg ggagccagca tggatctggc tggacccgat
1381 gctgtccaga actgggaagg ccacaggggt ggggcagcca tcccggccat tctgaggtat
1441 gacattcctc cccggccaca ctcctcaaga cacatccaga gactgttgct gtctgtgggc
1501 agagttctgt gttctggcca atgtgaccgt agtgccgggg actgggggag gtgggttgga
1561 tgtgcttgcc acccccccgg ctaagctccc ccttctgctg aaccatgatc cccaccccct
1621 ccgccggtca gtctcccata ccttatttat tggagtggag ggggaagccc atgggagaat
1681 tttggggatg ttttggtctt ttcttccttt tgtaataaaa attatttaag ttgttagaaa
1741 aaaaaaaaaa aaaaaaaaaa
//